Clinical trials: Amputee
Lower Limb Amputation
Walking Strategies in Usual Locomotion of Lower Limb Amputees
Amputation is a life-altering event with an immediate and obvious effect on daily life activities and quality of life. Asymmetrical movements of the lower limbs and compensatory strategies during walking are associated with an…
- Trial name
- STRAAL (NCT05420623)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- FondationbHopale
Amputation
Comparing Intact and Residual Amputated Muscle
Lower limb amputees rely on their prosthetic to remain active and lead an independent life. In recent years, measuring residual muscle activity has been used to interpret a user's intent and thereby modulate prosthesis control.
- Trial name
- NCT06182202
- Testing
- Powered Prosthesis
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Amputation Arm and Hand, Unilateral Right, Amputation Arm and Hand, Unilateral Left
Neural Enabled Prosthesis for Upper Limb Amputees
This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.
- Conditions
- Amputation Arm and Hand, Unilateral Right, Amputation Arm and Hand, Unilateral Left, Prosthesis User
- Trial name
- NCT03432325
- Testing
- Neural Enabled Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Arkansas, Fayetteville
Amputation; Traumatic, Hand
To Assess the Utility of the Point Partial in a Clinical Take-home Study of Partial Hand Amputees
This study will allow us to assess whether the Point Partial confers functional and psychological benefit to persons with partial finger amputations in an unconstrained environment.
- Trial name
- NCT05012683
- Testing
- Point Partial
- Where
- 7 sites in United States
- Volunteers
- 11 people
- Sponsor
- Point Designs
Amputation
Reduction of Shear Forces Using Semi-flexible Sockets on Transtibial Amputees
The purpose of this graduate student research study, is to test two different sockets for comfort and test what pressures are created by the socket during daily activities.
- Trial name
- NCT03390153
- Testing
- semi flexible socket, rigid fiber socket
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Amputation, Amputation, Traumatic
Evaluation of Dexterous Terminal Device
Liberating Technologies, Inc. (LTI) has developed Pointdexter, a dexterous prosthetic fingertip that is integrated into a commercial prosthetic hand and allows for an additional fine grasp.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper
- Trial name
- NCT05840601
- Testing
- Pointdexter, Comparator
- Sponsor
- Liberating Technologies, Inc.
Leg Lower Amputation, Traumatic Amputation
The Injury and Its Consequences in the Sports Lower Limb Amputee
This study was motivated by the lack of data in the literature on the injury of the major lower limb amputee playing sports and its socio-professional impact. It aims to study sports-related injuries in lower limb amputees.
- Trial name
- PREV'AMP SPORT (NCT05059886)
- Testing
- completion of a questionnaire on the practice of sports and possible injuries
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Amputation, Phantom Limb Pain
Prosthesis With Sensations
Lower limb amputees suffer complete lack of sensory feedback of current available prostheses, which excludes the central nervous system from the correct sensory-motor integration.
- Conditions
- Amputation, Phantom Limb Pain, Sensory Deficit
- Trial name
- NCT03350061
- Testing
- SENSY
- Where
- Serbia
- Volunteers
- 3 people
- Sponsor
- Clinical Centre of Serbia
Amputation
Enhanced Auto-Diagnostic Adaptive Precision Trainer for Myoelectric Prosthetic Users
The eADAPT training consists of a variety of mobile games played on a mobile app (phone or tablet). A band is worn on the residual limb. Participants use muscle activation to send signals to execute certain movements in the game.
- Trial name
- eADAPT (NCT04238533)
- Testing
- eADAPT training, Conventional training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Amputees
Traumatic Below-knee Amputees With Prosthetics: Health-related Quality of Life and Locomotor Capabilities
The present study assesses the health-related quality of life and the locomotor capabilities major traumatic lower limb amputees who use prosthesis.
- Trial name
- NCT02439463
- Testing
- Below-knee amputation
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- Helsinki University Central Hospital
Amputation
EmPOWERing Active Seniors With Energy
A pilot study comparing the emPOWER Ankle System to standard carbon fiber prosthetic feet, in active seniors.
- Trial name
- EASE (NCT02958553)
- Testing
- emPOWER Ankle, Subject's own passive prosthesis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Prostheses and Implants
Advanced Prosthetic Devices for Lower Limb Amputees
Lower limb amputation is an emerging global health concern. Currently, there are over 1.6 million amputees in the U.S. and around 6000 new amputations are recorded per annum in the UK.
- Trial name
- NCT04197011
- Testing
- prosthetic device
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Lower Limb Amputation at Ankle (Injury)
Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees
Evaluate a new porosthetic device in lower limb amputees.
- Trial name
- PROPRIO-FOOT (NCT02501408)
- Testing
- propriofoot prosthesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Unilateral Trans-tibial Amputees
Hull Early Walking Aids for Transtibial Amputees - Randomised Control Trial (HEART)
Early walking aids are routinely used in UK for rehabilitation of patients with below knee amputations. The two main walking aids used commonly in practice include the non-articulated Pneumatic Post Amputation Mobility Aid…
- Trial name
- HEART (NCT01024023)
- Testing
- EWA
- Where
- 3 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Hull
Amputees
Cortical Activation in Individuals With Finger Amputation During Mirror Versus Imagery Treatment
Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment…
- Trial name
- NCT02838485
- Testing
- Mirror, Imagery
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Lower Extremity Amputation, Trans-Tibial Amputation
Kinematics of Ewing Amputees
The agonist-antagonist myoneural interface (AMI) construct, known as the Ewing amputation at the trans-tibial level, has been shown to create a bi-directional neural communication platform as a means of controlling and…
- Conditions
- Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
- Trial name
- NCT06371209
- Testing
- Modified Amputation, Standard Amputation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Brigham and Women's Hospital
Amputation, Traumatic
Isokinetic Parameters and the Amputee Mobility Predictor Scale
There is very limited research examining isokinetic parameters and activity level in patients with amputation.. Therefore, the aims of this study were to illustrate isokinetic measurements including strength and proprioception…
- Trial name
- NCT05188599
- Testing
- İsokinetic assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Gait, Balance
Gait Stability of People With Lower-limb Amputations
The purpose of this study is to evaluate whether there are quantifiable differences in walking stability, as measured by the acceleration of the trunk or the variation in step length, between people with unilateral below-knee…
- Trial name
- NCT00915109
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kim Parker
Transfemoral Amputees
Impairment Oriented Versus Task Oriented Gait Training In Transfemoral Amputee Rehabilitation.
This study examines the comparison between Impairment Oriented versus Task Oriented Gait Training in Transfemoral Amputee Rehabilitation.
- Trial name
- NCT07578051
- Testing
- Impairment oriented (Group A), Task oriented (Group B)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Amputation
Weight-bearing Exercise for Trans-tibial Amputees
A simple weight-bearing exercise has been designed using off-the-shelves devices (Nintendo Wii Balance Board) and centre of pressure (COP) analysis software (Python) for trans-tibial amputees receiving their first prosthesis.
- Trial name
- Prototest (NCT05095805)
- Testing
- additional weight-bearing exercise, standard weight-bearing exercise
- Where
- Slovenia
- Volunteers
- 20 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia