Clinical trials: Alteration of Cognitive Function
Cognitive Change, Reaction Time
Effects of A-GPC on Reaction Time and Cognitive Function
This is a randomized, double blind, crossover design study which measures the effect of alpha-glycerylphosphorylcholine (A-GPC) on reaction time and cognitive function in non-resistance trained males and females.
- Trial name
- NCT03903250
- Testing
- A-GPC, Sugar
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Cognitive Change, Stress, Psychological
Psychological Effects of 8 Weeks Supplementation With Sceletium Tortuosum Extract
This study employs a randomized controlled trial to test the cognitive enhancing and stress relieving potential of the product Zembrin® in healthy adults when consumed over an 8 week period.
- Trial name
- ZEMBRIN (NCT05471804)
- Testing
- Sceletium tortuosum
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Learning Disorders, Learning Disabilities
Efficacy of the MovinCog Intervention in Children
This study aims to test the efficacy of the MovinCog Intervention to enhance cognitive abilities in children 7-15 yrs. The intervention consists of two parts: a physical exercise regimen, based on high-intensity training, and a…
- Conditions
- Learning Disorders, Learning Disabilities, Cognitive Change
- Trial name
- NCT03255499
- Testing
- Exercise, Cognitive, Active control
- Where
- New Zealand
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Physiological Stress, Cognitive Change
Effects of Prebiotics on Cognition and Health
This research intervention aims to examine the effects of prebiotic consumption on changes in behavioral and biological measures of cognition and stress among adults.
- Conditions
- Physiological Stress, Cognitive Change, Gastrointestinal Health
- Trial name
- EPOCH-2 (NCT04551937)
- Testing
- Lactose Free 1% Milk, Lactose Free 1% Milk + 10 g prebiotic
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Inflammation, Inflammatory Response
Cannabis Observational Study on Mood, Inflammation, and Cognition
This project examines the effects of cannabis on cognition and other domains of function and whether those effects are dependent upon the ratio of THC to CBD in the product.
- Conditions
- Inflammation, Inflammatory Response, Mood, Cognitive Change
- Trial name
- COSMIC (NCT03522103)
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dehydration, Cognitive Change
The Effects of Hydration on Gut Health and Thinking
The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool.
- Conditions
- Dehydration, Cognitive Change, Gastrointestinal Microbiota
- Trial name
- WatUP (NCT05315531)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alteration of Cognitive Function
Cognitive Effects of Tai Chi Chuan in Healthy Older Adults and Older Adults
Background: Promotion of cognitive functions of middle aged and older adults and prevention of dementia are important issues in the aging society.
- Trial name
- NCT02270320
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Aerobic Exercise, Cognitive Change
The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults
Cumulative evidence indicates that a single bout of exercise has beneficial impacts on memory in young adults. From a physiological perspective, acute exercise leads to changes of heart rate variability (HRV), which is associated…
- Trial name
- TEEMY (NCT04861818)
- Testing
- Moderate-intensity aerobic exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Alzheimer Disease
SV2A-PET/CT and PET/MRI Combined Clinical Criteria Score in the Diagnosis of Early Cognitive Alteration
Using SV2A-PET to character a cohort of patients with early cognitive impairment using the novel synaptic probe 18F-labeled difluoro-analog of UCB-J（also known as 18F-SDM-8）
- Trial name
- NCT06445582
- Testing
- [18F]SDM-8
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Dementia, Mild Cognitive Impairment
Video Games to Track Cognitive Health
The purpose of this study is to assess cognitive function using a rapid, portable, computerized neurocognitive testing device in a wide variety of clinical settings.
- Conditions
- Dementia, Mild Cognitive Impairment, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT03608722
- Testing
- SLUMS, MMSE, MoCA
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- BrainCheck, Inc.
Cognitive Change, Well-Being, Psychological
Acute Effects of Physical Activity on Cognition and Well-being in University Students
Previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions.
- Trial name
- ActClass4Brain (NCT06168526)
- Testing
- Acute physical activity
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Cognitive Change
Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy
Transcranial Light Therapy involves non-invasive and invisible beams of light that increase energy metabolism in the brain. Transcranial light therapy has been found to promote brain metabolism.
- Trial name
- NIR-Flow (NCT03740152)
- Testing
- Transcranial Light Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mood, Cognitive Change
OxPALM: Oxford Study on Probiotics and Low Mood
Probiotics are live bacteria which have been suggested to have beneficial effects not only on gut function but also on psychological and cognitive functioning.
- Trial name
- NCT03801655
- Testing
- Bio-Kult
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cognitive Dysfunction, Cognitive Impairment
CAMCI: Advancing the Use of Computerized Screening in Healthcare
Cognitive impairment is a significant health problem in the United States, resulting in costs over $100 billion a year. We will provide an efficient, effective, and financially intelligent solution to Primary Care Physician's to…
- Conditions
- Cognitive Dysfunction, Cognitive Impairment, Cognitive Decline, Cognitive Change
- Trial name
- NCT03512301
- Testing
- CAMCI, MoCA, Clinical Adjudication
- Where
- 4 sites in United States
- Volunteers
- 773 people, healthy volunteers welcome
- Sponsor
- Psychology Software Tools, Inc.
Environmental Exposure, Physical Activity
Neurophysiological Mechanisms of Physical Activity Interventions in Unique Environments
This randomized intervention is designed to compare the influence of physical activity in natural and urban environments on cognitive and physical health.
- Trial name
- NCT03501953
- Testing
- Physical Activity
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northeastern University
Cognitive Change
Effects of Seaweed Extract on Mental Performance Following a High-carbohydrate Meal
The current study will explore the impact of seaweed extract on cognitive function following a high-carbohydrate meal at a number of time-points post-consumption.
- Trial name
- NCT03328923
- Testing
- 500mg brown seaweed powder
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Overweight and Obesity, Cognitive Change
Acute Effects of Exercise Combined With Ketone Ester Supplement
To examine the acute changes in cardiometabolic and neurocognitive outcomes in response to exercise combined with ketone ester supplement in overweight/obese adults.
- Conditions
- Overweight and Obesity, Cognitive Change, Ketoses, Metabolic
- Trial name
- NCT06365957
- Testing
- Ketone monoester supplementation, High-intensity interval exercise, Moderate-intensity continuous exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Macau
Cognitive Change, Affect
Cognitive Effects of Mint Essential Oil
This study investigates the cognitive and mood effects of mint essential oils in a group of healthy, human adults. The investigational product will also be tested in vitro to ensure a number of biological mechanisms.
- Trial name
- NCT03475836
- Testing
- Mentha piperita
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Caffeine, Diet, Healthy
Acute Effects of Fitness Drink Formulas on Energy Expenditure and Fat Metabolism
The purpose of this investigation was to examine the acute effects of consuming two different fitness drink formulas on the physiological response at rest and to exercise in healthy men and women.
- Conditions
- Caffeine, Diet, Healthy, Fat Burn, Cognitive Change
- Trial name
- NCT04455009
- Testing
- Fitness Drink Formula
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Central Florida