Clinical trials: Allergy to Peanut
Food Hypersensitivity, Hypersensitivity
A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial
The purpose of this study is to evaluate the safety and immune response to daily sublingual (under the tongue) immunotherapy (SLIT) with peanut extract in adults and children with peanut allergies.
- Conditions
- Food Hypersensitivity, Hypersensitivity, Immediate Hypersensitivity, Peanut Hypersensitivity
- Trial name
- NCT00580606
- Testing
- Glycerinated peanut allergenic extract
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Peanut Hypersensitivity
A Study of Xolair in Peanut-Allergic Subjects Previously Enrolled in Study Q2788g
This is a Phase IIb, multicenter, open-label study available to active (Xolair) and control (placebo) subjects who have completed their final visit (or early termination visit, if applicable) for Study Q2788g, who meet the…
- Trial name
- NCT00382148
- Testing
- omalizumab
- Volunteers
- 11 people
- Sponsor
- Genentech, Inc.
Peanut Allergy
Tolerance Following Peanut Oral Immunotherapy
The unifying objective of this project is to determine whether peanut oral immunotherapy (PN OIT) induced clinical tolerance in the context of food allergy is significantly associated with the expansion of a specific regulatory T…
- Trial name
- PNOIT2 (NCT01750879)
- Testing
- Peanut Flour, Oat Flour
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Massachusetts General Hospital
Peanut Allergy
Reduction of Peanut Reactivity and Immune Modulation With Anti-IgE Therapy
This pilot study is will examine the pathways involved in allergic response, primarily in food allergy; specifically peanut allergy.
- Trial name
- NCT02194530
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Allergy to Peanut
Predictors of Persistent Peanut Allergy at Age 5 Years
The purpose of this study is to determine if avoidance of peanut by children with positive allergy testing to peanut in the first 5 years of life increases the likelihood of developing a persistent peanut allergy by age 5 years.
- Trial name
- NCT02497261
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Peanut Allergy
Safety of Epicutaneous Immunotherapy for the Treatment of Peanut Allergy
The purpose of this phase 1b study is to evaluate the safety and tolerability of repeated epicutaneous applications of peanut proteins using a patch delivery system (Viaskin device) in peanut allergic subjects.
- Trial name
- NCT01170286
- Testing
- Whole peanut extract
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- DBV Technologies
Peanut Hypersensitivity
Boiled Peanut Oral Immunotherapy
Prospective Phase 1 clinical trial providing proof of concept data on boiled peanut oral immunotherapy (OIT) for the treatment of peanut allergy in children.
- Trial name
- BPOIT (NCT04090203)
- Testing
- Boiled Peanut Powder
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Alton Melton
Food Allergy
Prevalence of Food Allergies to Proteins From Different Legumes
The objective of the study is to assess the prevalence of a sensitization to proteins from legumes by skin prick test using commercial extracts (peanut, soy, and pea) and raw material (lupin) in atopic and healthy subjects.
- Trial name
- NCT01728168
- Where
- Germany
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Jena
Food Allergy Peanut
Novel Treatment for Patients With Peanut Allergy: Intralymphatic Immunotherapy
Use of three intralymphatic injections of peanut allergen one month apart to induce tolerance to peanut in peanut allergic people.
- Trial name
- NCT04200989
- Testing
- Peanut allergen
- Where
- United States
- Sponsor
- Scripps Health
Allergy to Egg, Allergy to Peanut
Basophil Activation Test (BAT) Sensitivity in Child Food Allergy
Child food allergy represent 6 to 8% of child in industrialised country. Within this allergy, peanuts and egg allergy are one of the most common.
- Trial name
- TAB-TPO (NCT01966640)
- Testing
- Basophil Activation Test
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Rouen
Food Allergy, Food Allergy in Children
Understanding the Immune System's Role in Tree Nut and Peanut Allergies: Key Biomarkers for Diagnosis and Treatment Monitoring and Treatment Targets
Peanut and tree nuts belong to the main elicitors of pediatric food allergy and are the main cause of near fatal reactions in children requiring emergency management.
- Conditions
- Food Allergy, Food Allergy in Children, Food Allergy Peanut, Tree Nut Allergies
- Trial name
- Markers4Care (NCT06554691)
- Where
- 2 sites in Luxembourg
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Peanut Allergy
Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy
This clinical research study investigates the safety, tolerability and efficacy of a peanut SLIT-tablet in adults, adolescents, and children with peanut allergy.
- Trial name
- NCT05440643
- Testing
- Peanut SLIT-tablet
- Where
- 42 sites in United States, Canada
- Volunteers
- 209 people
- Sponsor
- ALK-Abelló A/S
Peanut Allergy
Oral Immunotherapy for Peanut Allergic Patients
Multicenter, double-blind, randomized, placebo-controlled phase I/II study to determine the safety, tolerability, potential efficacy and dose finding of INP20, an oral immunotherapy in peanut-allergic patients.
- Trial name
- NCT04163562
- Testing
- INP20
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- InnoUp Farma S.L.
Allergy
A Safety and Efficacy Study of Xolair in Peanut Allergy
This is a 38-week, randomized, double-blind, placebo-controlled, parallel group trial of approximately 150 patients who have a history of immediate hypersensitivity reaction to peanut protein.
- Trial name
- NCT00086606
- Testing
- Xolair (omalizumab)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Genentech, Inc.
Food Hypersensitivity, Peanut Hypersensitivity
Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study
Food allergy affects up to 10% of the population. The mainstay of management involves dietary avoidance and provision of rescue medication in the event of an accidental reaction.
- Trial name
- TRACEextension (NCT02665793)
- Testing
- DBPCFC to peanut cookie, Single-dose DBPCFC to peanut flour, Single-dose DBPCFC to peanut butter
- Volunteers
- 17 people
- Sponsor
- Imperial College London
Allergy, Peanut, Peanut Allergy
Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients
This is a phase II trial that aims at evaluating the safety and tolerability of oral encapsulated fecal microbial transplantation therapy (MTT) in peanut allergic patients.
- Conditions
- Allergy, Peanut, Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis
- Trial name
- NCT05695261
- Testing
- Microbial Transplantation Therapy, Antibiotic, Oral Immunotherapy (OIT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Rima Rachid
Peanut Allergy
ARTEMIS Peanut Allergy In Children
The purpose of this study is to demonstrate the efficacy and safety of AR101 through oral immunotherapy (OIT) in peanut-allergic children.
- Trial name
- ARTEMIS (NCT03201003)
- Testing
- AR101 powder provided in capsules & sachets
- Where
- 18 sites in France, Germany and 5 more
- Volunteers
- 175 people
- Sponsor
- Aimmune Therapeutics, Inc.
IgE-Mediated Cow Milk Allergy, Peanut Allergy
Using Commonly Available Food Products To Treat Food Allergy
Food allergy affects 1 in 30 children, and is the commonest trigger for life-threatening reactions (anaphylaxis) in this age group.
- Trial name
- NATASHA (NCT05503446)
- Testing
- Peanut in common foods or supermarket-sourced cow's milk (CM)
- Where
- 5 sites in United Kingdom
- Volunteers
- 216 people
- Sponsor
- University of Southampton
Food Allergies, Peanut Allergies
A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment)
The goal of this observational study is to learn about the long-term outcomes of children and young people who underwent an 18-month course of oral immunotherapy (OIT) treatment for peanut, egg or milk allergy.
- Conditions
- Food Allergies, Peanut Allergies, Egg Allergy, Milk Allergy
- Trial name
- LPEM (NCT07359183)
- Where
- Australia
- Volunteers
- 147 people
- Sponsor
- Murdoch Childrens Research Institute
Oral Immunotherapy for Food Allergy, Tree Nut Allergy
The NACHO Trial (Nut Allergy Children OIT)
Most food allergies that begin in early childhood are mild and resolve by school age, but nut allergies persist in about 80-90% of individuals into adulthood.
- Conditions
- Oral Immunotherapy for Food Allergy, Tree Nut Allergy, Cashew Nut Allergy
- Trial name
- NCT06930950
- Testing
- Cashew nut oral immunotherapy
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- HUS Skin and Allergy Hospital