Clinical trials: Allergy in Children
Cow's Milk Allergy
Infant Formula in Infants and Children With Cow's Milk Allergy
This is a multi-center, randomized, double-blinded, placebo-controlled food challenge to be conducted in infants and children with confirmed IgE-mediated cow's milk allergy (CMA), followed by a 7-day open feeding of the…
- Trial name
- NCT06456541
- Testing
- Experimental Extensively Hydrolyzed Formula
- Where
- 9 sites in United States
- Volunteers
- 96 people
- Sponsor
- Abbott Nutrition
Asthma
Effect of Medical Food on Reducing Asthma Symptoms in Asthmatic Children
To determine the effect of medical food on reducing asthma symptoms in asthmatic children.
- Trial name
- NCT01087710
- Testing
- medical food with EPA and GLA, vitamins and minerals, medical food minus EPA and GLA, antioxidant vitamins/minerals
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Abbott Nutrition
Reflex Epilepsy, Photosensitive, Eyeglasses
Efficacy of Lenses in Abolishing Photoparoxysmal Responses
Background. Blue lenses that filter out red light have been proposed as a new therapeutic alternative for patients with PSE, such as the lens Zeiss Clarlet Z1.
- Trial name
- PPRs (NCT04076410)
- Testing
- Z1 lens, Experimental Lens 1, Experimental Lens 2
- Where
- 2 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- Aston University
Asthma in Children
Factors Influencing Pediatric Asthma
Asthma is a chronic lung disease with serious morbidity and potential mortality. Multiple physiologic, environmental and social conditions impact the prevalence and severity of asthma.
- Trial name
- FIPA (NCT03302962)
- Testing
- Intensive Asthma Education
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Missouri Breaks Industries Research, Inc.
Atopic Dermatitis
Use of Complementary and Alternative Medicine in Children and Adults With Atopic Dermatitis
Complementary and alternative medicine are increasingly used all around the world and more specifically in chronic diseases such as atopic dermatitis.
- Trial name
- NCT05833880
- Testing
- Self-administered questionnaire
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Central Hospital, Nancy, France
Cow's Milk Protein Allergy (CMPA)
TeriFort 1+ Study: Efficacy and Safety of an Extensively Hydrolyzed Formula in the Management of Cow's Milk Protein Allergy in Young Children: A Prospective, Single-Arm Interventional Study (TeriFort 1+)
This study aims to evaluate the clinical effect, as reported by physicians, of an extensively hydrolyzed formula in young children aged 1~3 years with diagnosed with or highly suspected CMPA in a real-world clinical practice…
- Trial name
- NCT07855796
- Testing
- Diagnosed with or highly suspected CMPA: Extensively Hydrolyzed Formula intervention
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Teyi Yinuo Health Technology Co., Ltd.
Peanut Allergy
Viaskin® Peanut (DBV712) Expanded Access Protocol
This is an open label expanded access program for male and female patients ≥ 4 years old.
- Trial name
- NCT04371627
- Testing
- Viaskin Peanut
- Sponsor
- DBV Technologies
Asthma, Asthma in Children
Allergy, Asthma, and Atopic Eczema in Finland
The summary is available at --> https://www.finnatopy.fi/summary
- Conditions
- Asthma, Asthma in Children, Allergy, Rhinitis, Allergic
- Trial name
- FinnATOPY (NCT06330974)
- Testing
- No intervention, No Intervention: Observational Cohort
- Where
- Finland
- Volunteers
- 1,200,000 people
- Sponsor
- Tampere University
Food Allergy in Children
Allergy to Almond in Children
Allergy to tree nuts are frequent in children but allergy to almond is one of the less described tree nuts allergy. The main objective of our study is to determine diagnostic values of skin prick-tests and specific IgE to almond…
- Trial name
- NCT04407104
- Testing
- skin prick-test
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Nursing Caries, Pain
The Effect of Hand Puppets and Kaleidoscope on Pain and Fear in Preschool Children
This study aimed to determine the effects of hand puppets and kaleidoscopes on some emotional parameters in preschool children who underwent skin prick testing at the pediatric allergy and immunology outpatient clinic.The study…
- Conditions
- Nursing Caries, Pain, Fear of Pain
- Trial name
- NCT06512857
- Testing
- Hand puppet method, Kaleidoscope method
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Firat University
Dermatitis, Atopic
Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis
Atopic dermatitis, also called eczema, is characterized by redness, papulation (skin elevation) and pruritus (skin itching). The active ingredient of pimecrolimus inhibits the T-cell activation.
- Trial name
- NCT00121381
- Testing
- Pimecrolimus plus topical corticosteroid (TCS)
- Where
- 13 sites in United States
- Volunteers
- 400 people
- Sponsor
- Novartis
Allergy in Children
Allergen Provocations- HCA Children's Hospital
A prospective study of all allergen provocations performed in children at the Hans Christian Andersen Children's Hospital.
- Trial name
- NCT04331522
- Testing
- Oral provocation test
- Where
- Denmark
- Volunteers
- 8,000 people
- Sponsor
- Josefine Gradman
Allergy Milk
Step Down Approach in Children With Cow Milk Allergy
Cow's milk allergy (CMA) affects up to 3% of European children. In the absence of an alternative to cow's milk, the management of CMA is based on the use of safe, affordable and nutritionally adequate formulas.
- Trial name
- SDACMA (NCT03449537)
- Testing
- extensively hydrolyzed casein formula + LGG, Hypoallergenic formula based on amino-acid based formula
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Hematological Malignancies
Impact of Child Positioning on Pain During a Lumbar Puncture
This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.
- Trial name
- PHIPA-PEPL (NCT02834156)
- Testing
- LP in a seated position then LP in a lying position, LP in a lying position then LP in a seated position
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hypomineralized Second Primary Molars, Dental Hypersensitivity
Prevalence of Hypomineralized Second Primary Molars and Their Association with Dental Hypersensitivity in Egyptian Children
hypomineralized second primary molars and dental hypersensitivity in a group of Egyptian children
- Trial name
- NCT06753695
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Cairo University
Status Asthmaticus
The Role of Ketamine as an Adjuvant Therapy for Children With Acute Status Asthmaticus
The purpose of this investigation is to perform a pilot study assessing the safety and utility of intravenous ketamine as an adjuvant therapy in the emergency department setting for pediatric patients in acute status asthmaticus…
- Trial name
- NCT03338205
- Testing
- Ketamine
- Sponsor
- Augusta University
Severe Uncontrolled Asthma
PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma
This study will evaluate the PK, PD and long-term safety of Benralizumab administered subcutaneously in 30 children aged 6 to 11 years with severe eosinophilic asthma.
- Trial name
- TATE (NCT04305405)
- Testing
- Benralizumab
- Where
- 15 sites in United States, Japan
- Volunteers
- 30 people
- Sponsor
- AstraZeneca
Allergic Rhinitis
Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis
The purpose of the trial is to compare the efficacy and safety of sublingual seasonal and annual immunotherapy in children with allergic rhinitis allergic to grass pollens.
- Trial name
- NCT00698594
- Testing
- sublingual allergen extract
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lodz
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Otitis Media With Effusion, Food Hypersensitivity
Food Allergy - Tubes - Adenoids (FATA) Trial
The questioned proposed by this study is one of treatment: "To what extent does simultaneous BMT (Bilateral Myringotomy with Tympanostomy Tubes), adenoidectomy, and diagnosis/avoidance of food allergy affect the frequency of…
- Trial name
- FATA (NCT00736112)
- Testing
- Food Allergy Testing, Adenoidectomy, BMT
- Where
- United States
- Sponsor
- University of Missouri-Columbia