Clinical trials: Allergy in Children
Asthma, Wheeze
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
The study will ascertain the ability of preschool lung function tests to distinguish healthy children from those with wheeze, and to differentiate phenotypes of wheezy children (high and low risk for asthma as defined by API) in…
- Conditions
- Asthma, Wheeze, Obstructive Sleep Apnea, Food Allergy
- Trial name
- WheezyER (NCT02743663)
- Testing
- Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma
Early Diagnosis of Asthma in Young Children
The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements
- Trial name
- NCT00422747
- Testing
- beclomethasondipropionate
- Where
- Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Food Allergy, Food Allergy in Children
Effect of Omalizumab in the Skin of Food Allergy Patients
The goal of this interventional study is to evaluate whether skin barrier abnormalities occur in subjects with a food allergy, as determined by positive oral food challenge (OFC).
- Trial name
- NCT06618963
- Testing
- Omalizumab Injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Bilateral Sensorineural Hearing Loss, Cochlear Implant
Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation
There is a rapidly growing population of adult and pediatric cochlear implant (CI) recipients with acoustic hearing preservation in the implanted ear(s) allowing for combined Electric and binaural Acoustic Stimulation (EAS).
- Conditions
- Bilateral Sensorineural Hearing Loss, Cochlear Implant, Hearing Preservation, Electric and Acoustic Simulation
- Trial name
- NCT07356128
- Testing
- binaural processing over time, binaural processing over time for children and adults with normal hearing
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hearts for Hearing
Nursing Caries, Pain
The Effect of Hand Puppets and Kaleidoscope on Pain and Fear in Preschool Children
This study aimed to determine the effects of hand puppets and kaleidoscopes on some emotional parameters in preschool children who underwent skin prick testing at the pediatric allergy and immunology outpatient clinic.The study…
- Conditions
- Nursing Caries, Pain, Fear of Pain
- Trial name
- NCT06512857
- Testing
- Hand puppet method, Kaleidoscope method
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Firat University
Hypomineralized Second Primary Molars, Dental Hypersensitivity
Prevalence of Hypomineralized Second Primary Molars and Their Association with Dental Hypersensitivity in Egyptian Children
hypomineralized second primary molars and dental hypersensitivity in a group of Egyptian children
- Trial name
- NCT06753695
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atopy, Atopic Dermatitis Eczema
Breast Milk: Influence of the Micro-transcriptome Profile on Atopy in Children Over Time
This is an observational cohort study of 221 breast-feeding mother-infant dyads delivered at term. The goal of the study is to investigate whether levels of immune-related microRNAs (miRNAs) in maternal breast milk (MBM)…
- Conditions
- Atopy, Atopic Dermatitis Eczema, Wheezing, Food Allergy in Infants
- Trial name
- IMPACT (NCT04017520)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Asthma
Redesigning Ambulatory Care Delivery to Enhance Asthma Control in Children
The investigators have developed a tool to facilitate asthma self-management in children, the electronic-AsthmaTracker (e-AT). The e-AT changes ambulatory asthma care delivery to a new model that is continuous and proactive…
- Trial name
- NCT02409277
- Testing
- Experimental: Standard vs Intensive e-AT Intervention
- Where
- United States
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- University of Utah
Adenoid Hypertrophy, Allergy
Periostin Levels in Children With Adenoid Hypertrophy
This prospective observational study evaluated serum and tissue periostin levels in children with adenoid hypertrophy. Children with grade 3-4 adenoid hypertrophy who were scheduled for adenoidectomy were compared with children…
- Conditions
- Adenoid Hypertrophy, Allergy, Allergic Rhinitis
- Trial name
- NCT04152746
- Testing
- Periostin level
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Atopic Dermatitis
Vitamin D Treatment Effect for Atopic Dermatitis in Children
A double-blind study to evaluate the role of human microbiome and vitamin D in the development of atopic dermatitis.
- Trial name
- NCT05523986
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Asthma, Atopy
The JOIN Project: The Air in Diagnosis and Prevention of Asthma and Allergy
The JOIN project combines the health and indoor environment research areas to contribute in the development and validation of a new asthma diagnosis method through exhaled VOC analysis.
- Trial name
- JOIN (NCT02802891)
- Where
- Portugal
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Hypomineralization Molar Incisor
Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Introduction: Photobiomodulation (PBM) shows promising results for the complementary treatment of dentin hypersensitivity; however, few studies have evaluated this treatment specifically for teeth affected by molar incisor…
- Trial name
- NCT05370417
- Testing
- Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Asthma in Children
The Effect of Health Care Transition Based Education Given to Adolescents With Asthma
Aim: The purpose of this study was to examine the effect of health care transition-based education on transition readiness and self-efficacy in adolescents (14-18 years) with asthma through a randomized controlled experimental…
- Trial name
- NCT05550922
- Testing
- Healthcare Transition-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Allergy, Eczema
Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction
1. To determine if BCG immunisation at birth, compared to no BCG immunisation, leads to a reduction in measures of allergy and infection in the first 12 months of life. 2.
- Conditions
- Allergy, Eczema, Respiratory Tract Infections
- Trial name
- MIS BAIR (NCT01906853)
- Testing
- BCG
- Where
- 2 sites in Australia
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Asthma, Bronchiolitis
WheezoMeter® Correlation Study
The primary goal of the study is to more firmly establish correlations between WheezeRate(Wz%) and other parameters used to assess wheezing and asthma including spirometry, provider's auscultation, and symptoms at the time of Wz%…
- Trial name
- NCT01556958
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- iSonea
Asthma in Children, Vaccine Adverse Reaction
Safety of LAIV4 in Children With Asthma
This is a prospective randomized, open label clinical trial in approximately 300 children aged 5-11 years with a physician diagnosis of persistent asthma.
- Conditions
- Asthma in Children, Vaccine Adverse Reaction, Vaccine Reaction, Asthma
- Trial name
- NCT03600428
- Testing
- Live Attenuated Influenza Vaccine (LAIV), Inactivated Influenza Vaccine (IIV)
- Where
- 3 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Respiratory Tract Infections, Infections
Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
The goal of this clinical trial is to evaluate the off-target/non-specific effects of the measles-mumps-rubella (MMR) vaccine in children.
- Conditions
- Respiratory Tract Infections, Infections, Allergy, Eczema
- Trial name
- NEMAU (NCT05758532)
- Testing
- Measles-Mumps-Rubella vaccine (MMR)
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laure Pittet, MD-PhD
Bronchial Asthma, Signs and Symptoms, Respiratory
The Effect of Air Pollution on Lung Health Among Children Living in Haifa Bay Region, Israel
Haifa bay region is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region.
- Conditions
- Bronchial Asthma, Signs and Symptoms, Respiratory, Allergy
- Trial name
- NCT00718133
- Testing
- Spirometry (Pony spirometer)
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Atopic Dermatitis
Study to Examine the Benefits of Fabric Made With Lyocell/Chitosan/Ceramide in the Treatment of Children With Mild to Moderate Eczema
The study will primarily focus on evaluating the benefits of using a lyocell/chitosan/ceramide fabric as a treatment for young children with mild or moderate eczema.
- Trial name
- NCT02224950
- Testing
- Non-medicated Emollient plus Lyocell/Chitosan Sleeve, Non-medicated Emollient plus Cotton Sleeve
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Penicillin Allergy
Feasibility Assessment of Risk Stratification and Oral Challenge in Hospitalized Children at Low Risk for Antibiotic Allergy
Children are often reported to have antibiotics allergies, with approximately 10% of the US population labeled as allergic to an antibiotic.
- Trial name
- NCT04441021
- Testing
- Penicillin Allergy Risk Stratification and Evaluation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center