Clinical trials: Allergies
Asthma
Pharmacokinetic and Pharmacodynamic Profiles of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients With Asthma
The primary objective of this study is to compare the pharmacokinetic (PK) profiles of Albuterol Spiromax® and ProAir HFA after administration of a single inhaled dose of 180 mcg albuterol base from each product.
- Trial name
- NCT01844401
- Testing
- Albuterol Spiromax®, ProAir® HFA
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Self Efficacy, Asthma
The Effect of Online Peer and Adult Education Given to Adolescents With Allergic Asthma
Objectives: To examine the effect of interactive online education given by peers or adults on anxiety, self-efficacy, quality of life, and disease knowledge and management in adolescents with allergic asthma in the 10-14 age…
- Conditions
- Self Efficacy, Asthma, Asthma in Children
- Trial name
- NCT06045312
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Aydin Adnan Menderes University
Asthma
Asthma Learning Project
The purpose of this study is to determine the effect on knowledge and behavior of playing an educational asthma computer game during a pediatric Emergency Department (ED) asthma visit among children ages 7 - 15 years.
- Trial name
- ALP (NCT00874900)
- Testing
- Educational game, Educational game + motivational interview, Motivational interview
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Seattle Children's Hospital
Ovarian Cancer, Fallopian Tube Cancer
Vorinostat, Carboplatin and Gemcitabine in Women With Recurrent, Platinum-Sensitive Ovarian Cancer
This trial is a Phase Ib/II study of carboplatin/gemcitabine/vorinostat for the treatment of platinum sensitive recurrent ovarian cancer.
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- NCT00910000
- Testing
- Vorinostat, Carboplatin, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Dana-Farber Cancer Institute
Bronchial Asthma
Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05).
The aim of the study is to investigate the effect of roflumilast (APTA-2217) on lung function in patients with asthma. Roflumilast will be administered orally once daily.
- Trial name
- NCT00242307
- Testing
- Roflumilast
- Where
- Japan
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Allergic Rhinitis
Yoga Training in Allergic Rhinitis Patients
The purpose of this study was to investigate effects of yoga training on rhinitis symptoms and cytokines in allergic rhinitis patients.
- Trial name
- NCT03700944
- Testing
- Yoga training
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Chulalongkorn University
Severe Asthma
Follow-up of Children With Severe Asthma at Adult Age
Most of clinical cohorts focused on the course of asthma over time and on the different phenotypes of asthma have investigated children and adults separately. The passage from childhood to adulthood is scarcely explored.
- Trial name
- S2AEA (NCT05032209)
- Testing
- follow-up of children with severe asthma in adulthood
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Chronic Spontaneous Urticaria (CSU), Chronic Idiopathic Urticaria
A Study to Assess the Efficacy and Safety of THB335 in Adults With Chronic Spontaneous Urticaria (CSU)
THB335-201 is a Phase 2, randomized, double-blind, placebo-controlled, parallel-group, multicenter study in adults with CSU who remain symptomatic despite standard-of-care treatment.
- Trial name
- NCT07766499
- Testing
- THB335 Lower Dose, THB335 Higher Dose
- Volunteers
- 81 people
- Sponsor
- Calixis Inc.
Dermatitis, Atopic, Eczema
Comparative Study of Crisaborole vs. Tacrolimus in Atopic Dermatitis
This study will compare the efficacy and safety of crisaborole ointment with tacrolimus ointment, in the treatment of patients with mild-to-moderate atopic dermatitis.
- Trial name
- NCT07367932
- Testing
- Application of crisaborole twice daily, Tacrolimus ointment in atopic dermatitis
- Volunteers
- 30 people
- Sponsor
- Cairo University
Allergy
Direct Oral Challenges in Private Practice Setting to Delabeling Children With Beta-lactam Allergy
The purpose of this study is to demonstrate the feasibility of direct oral challenge performed in private practice setting for children with suspected benign delayed allergy to beta-lactams.
- Trial name
- Betalactaville (NCT07002814)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Study of Oglemilast for the Treatment of Asthma
The purpose of this study is to determine whether oglemilast is safe and effective in the treatment of allergen-induced asthma.
- Trial name
- NCT00322686
- Testing
- Oglemilast
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Forest Laboratories
Irritable Bowel Syndrome
Effect of Butyrogenic Fibers in IBS Patients
Despite there being no clearcut advantages, one of the most common recommendations in IBS management is to increase the amount of dietary fibres. In some IBS patients fibres have a deleterious effect on pain and bloating.
- Trial name
- NCT00314886
- Testing
- Diet
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Asthma, COPD
Prehospital Emergency Care of Obstructive Respiratory Emergencies With the Use of Teleconsultation
The aim of the study is to investigate the quality of prehospital emergency care in acute respiratory emergencies, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644045
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- RWTH Aachen University
Bronchial Asthma
Antiepileptic Drug Carbamazepine in Treatment of Bronchial Asthma
The purpose of this study was evaluation the efficacy of antiepileptic drug carbamazepine in the treatment of mild-to-severe bronchial asthma.
- Trial name
- NCT00207428
- Testing
- Carbamazepine
- Volunteers
- 65 people
- Sponsor
- Centre of Chinese Medicine, Georgia
Pain, Inflammatory Response
Association Between Body Composition and Pain in Spinal Cord Injury
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and…
- Trial name
- NCT05459207
- Testing
- Moderate Fat Meal, High Fat Meal
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Healthy
Peripheral Effects of Endotoxin on Insulin Resistance
The aim of the study is to isolate the direct effects of endotoxin on glucose, lipid and protein metabolism. Eight healthy volunteers are enrolled.
- Trial name
- NCT00929136
- Testing
- USP endotoxin
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Asthma
BI 443651 Methacholine Challenge
The primary objective of this study is to investigate safety and tolerability of three consecutive administrations, 12 hours apart, at three different dose-levels of BI 443651 administered via oral inhalation in male and female…
- Trial name
- NCT03135899
- Testing
- BI 443651
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Boehringer Ingelheim
Seasonal Allergic Rhinitis
Can a Nasal Decongestant Test Predict Treatment Outcomes in Seasonal Allergic Rhinitis?
We hypothesize that those patients with purely seasonal allergic rhinitis will decongest better than those subjects with another cause contributing to their symptoms.
- Trial name
- NCT00618332
- Testing
- mometasone furoate nasal spray
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Asthma, Obesity
Contributing Factors in the Pathobiology of Airway Remodeling in Obesity
There are two aims for this study. The purpose of this study is to determine the effects of body weight and hormones on airway fibrosis (scarring) and lung function in obese \& lean asthma subjects compared to obese \& lean…
- Conditions
- Asthma, Obesity, Obesity, Morbid, Bariatric Surgery Candidate
- Trial name
- NCT03115632
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University