Clinical trials: Allergic Rhinoconjunctivitis
Rhinitis, Allergic, Rhinoconjunctivitis
Study to Evaluate the Efficacy and Safety of "Allergovac Poliplus" in Polysensitized Patients With Allergic Rhinitis/Rhinoconjunctivitis, With or Without Asthma
This is an observational prospective multicenter clinical study, to evaluate the efficacy and safety of the treatment with Allergovac Poliplus subcutaneous immunotherapy (SCIT) with a mixture of 2 allergenic extracts (pollens or…
- Trial name
- ARES (NCT03821077)
- Testing
- Allergen Immunotherapy (AIT)
- Where
- 10 sites in Spain
- Volunteers
- 122 people
- Sponsor
- Roxall Medicina España S.A
Allergy
A Trial of the ALK Grass Tablet in Subjects With Hayfever
This trial is performed to assess the efficacy and safety of the ALK Grass tablet for treatment of grass pollen induced rhinoconjunctivitis (hayfever).
- Trial name
- NCT00227279
- Testing
- ALK Grass tablet
- Where
- Denmark
- Volunteers
- 634 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergic Rhinitis
Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Grass Pollen
The objective of this trial is to assess the clinical efficacy of the modified extract (depigmented and polymerised with glutaraldehyde)of the subcutaneous injection of Phleum pratense pollen in the treatment of patients affected…
- Trial name
- NCT00916422
- Testing
- Allergen extract (Phleum pratense)
- Where
- 23 sites in Hungary, Spain
- Volunteers
- 153 people
- Sponsor
- Laboratorios Leti, S.L.
Seasonal Allergic Rhinitis, Hay Fever
Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR
Evaluate the relative efficacy of four dosing regimens of bilastine tablets (given either once or twice per day) versus placebo in patients with Seasonal Allergic Rhinitis (SAR) in the Mountain Cedar season in south Texas and…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Allergic Conjunctivitis, Hypersensitivity
- Trial name
- NCT00574379
- Testing
- Bilastine
- Where
- 13 sites in United States
- Volunteers
- 805 people
- Sponsor
- Faes Farma, S.A.
Allergic Rhinoconjunctivitis
Investigating Nasal and Ocular Immune Response to Conjunctival Allergen Exposure
The goal of this pilot study is to develop an eye allergen challenge model, called a conjunctival allergen challenge (CAC), using timothy grass as the allergen.
- Trial name
- INQUIRE (NCT07801625)
- Testing
- Standardized Allergen Extract, Timothy Grass (Phleum pratense)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Allergic Rhinoconjunctivitis
Dose-response Study With Subcutaneous Immunotherapy of an Standardized Dermatophagoides Pteronyssinus (DPT) Extract
As part of the registration plan of our products and after performing a Phase I study the present trial has been designed to compare the efficacy of 5 different doses of subcutaneous immunotherapy in depot presentation.
- Trial name
- NCT01564017
- Testing
- Allergovac depot
- Where
- 12 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Roxall Medicina España S.A
Allergic Rhinoconjunctivitis
Nasal Mucus Proteome and Immunotherapy
Nasal mucus as first line defense barrier of the nasal mucosa contains a variety of proteins that act as functional units. We recently showed that the nasal mucus proteome between allergic rhinitis patients and healthy controls…
- Trial name
- NCT02159404
- Testing
- Immunotherapy
- Where
- Austria
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Seasonal Allergic Rhinitis, Hay Fever
PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)
The purpose of this study is to evaluate the relative efficacy of four dosing regimens of bilastine tablets versus placebo in subjects with SAR exposed in controlled ragweed pollen using the EEC model based on the mean change…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Rhinoconjunctivitis
- Trial name
- NCT00574210
- Testing
- Bilastine
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- Faes Farma, S.A.
Allergic Rhinoconjunctivitis to Birch Pollen, With a Positive Skin Prick Test to Birch Pollen
Safety and Efficacy of Low-dose IL-2 in Birch Pollen Allergy
Several studies have reported a deficit and/or a defect in regulatory T cells in allergic subjects, which can be correlated with the allergic responses, especially for respiratory allergies.
- Trial name
- Rhinil-2 (NCT03776643)
- Testing
- ILT-101 ld-(IL2)
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Allergy
Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis
A phase III study to evaluate the efficacy and safety of SLIT for grass pollen allergens compared with placebo for reduction of symptoms and rescue medication usage in children.
- Trial name
- NCT00409409
- Testing
- 300 IR grass pollen allergen extract tablet
- Where
- Germany
- Volunteers
- 278 people
- Sponsor
- Stallergenes Greer
Ragweed Allergy, Rhinoconjunctivitis
ToleroMune Ragweed Follow up Study
Ragweed is the primary cause of autumn allergies. The ragweed season begins in mid-August. In the third National Health and Nutrition Examination Surveys54.3% of the population had positive test responses to one or more…
- Trial name
- NCT01448603
- Testing
- ToleroMune Ragweed
- Where
- Canada
- Volunteers
- 109 people
- Sponsor
- Circassia Limited
Allergy, Rhinoconjunctivitis
Immunotherapy With Depigmented and Polymerized Allergen Extract of Olea Europaea (GPIT)
The objective of this trial is to evaluate the clinical effectiveness of the administration of a depigmented and polymerized allergen extract of Olea europaea in the rhinitis or allergic rhinoconjunctivitis
- Trial name
- NCT00537342
- Testing
- Immunotherapy with modified extract of O. europaea pollen
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Laboratorios Leti, S.L.
Allergic Rhinoconjunctivitis
Changes in Specific Immunoglobulin and Blood Basophil Activity During Subcutaneous Immunotherapy in Allergic Rhinitis
The trial is randomized prospective study to examine the effects of subcutaneous immunotherapy on the adaptive immune system. The trial includes 30 participants randomized to treatment or control group.
- Trial name
- NCT01085526
- Testing
- Alutard phleum pratense subcutaneous immunotherapy, Alutard phl prat
- Volunteers
- 30 people
- Sponsor
- Aarhus University Hospital
Allergic Conjunctivitis, Allergic Rhinitis
Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis
Allergic conjunctivitis is one of the most common comorbidities of allergic diseases, especially of allergic rhinitis. Rhinoconjunctivitis is an allergic condition of the nasal mucosa and the eyes.
- Trial name
- NCT04532710
- Testing
- Eye Drops, Solution in Single-Dose Container
- Where
- Austria
- Volunteers
- 64 people
- Sponsor
- Marinomed Biotech AG
Rhino-conjunctivitis
Comparison of Different Up-dosing Schedules With Osiris Phleum Pratense
The purpose of this trial is to investigate the tolerability of Osiris Phleum pratense used with 2 simplified up-dosing schedules compared to the up-dosing schedule used in current practice.
- Trial name
- Osiris (NCT01425788)
- Testing
- Osiris Phleum pratense
- Where
- Poland
- Volunteers
- 236 people
- Sponsor
- ALK-Abelló A/S
Allergy
Safety and Efficacy of Recombinant Grass Pollen Allergen Cocktail in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of a recombinant grass Pollen allergen cocktail in allergic rhinoconjunctivitis
- Trial name
- NCT00309036
- Testing
- Recombinant grass pollen
- Where
- Germany
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Rhinoconjunctivitis
Quality of Life in Allergic Rhinoconjunctivitis Patients Treated With Dialyzable Leukocyte Extracts
The purpose of this study is to determine the changes of quality of life of patients with allergic rhinoconjunctivitis treated with standard medications plus Dialyzable Leukocyte Extracts (DLE).
- Trial name
- NCT02506998
- Testing
- DLE, Second generation anti histamines + Nasal corticosteroids
- Volunteers
- 30 people
- Sponsor
- National Polytechnic Institute, Mexico
Allergic Rhinitis Due to Grass Pollens
Study of Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Adult Patients With Allergic Grass Pollen Rhinoconjunctivitis
The purpose of the study is to assess the efficacy and safety of 300 IR sublingual tablet of grass pollen allergen extract compared to placebo in adult patient with allergic rhinoconjunctivitis.
- Trial name
- NCT00955825
- Testing
- 300 IR
- Where
- 19 sites in United States
- Volunteers
- 473 people
- Sponsor
- Stallergenes Greer
Seasonal Allergic Rhinitis, Asthma
Study of Grass-SPIRE in Subjects With Grass Allergies and Asthma
The purpose of this study is to determine whether it is safe to administer Grass-SPIRE to subjects suffering from both grass allergy and asthma
- Trial name
- NCT02161107
- Testing
- Grass-SPIRE
- Where
- 5 sites in Canada
- Volunteers
- 54 people
- Sponsor
- Circassia Limited
Allergic Rhinoconjunctivitis
Efficacy and Safety of Intraseasonal Specific Immunotherapy With Depiquick® Birch
This study will assess efficacy and safety of intraseasonal specific short-term immunotherapy with Depiquick® Birch in patients with allergic rhinitis and or rhinoconjunctivitis with or without intermittent asthma that have a…
- Trial name
- INSIDE (NCT01902992)
- Testing
- Depiquick Birch (DPG103)
- Where
- 35 sites in Germany
- Volunteers
- 202 people
- Sponsor
- Novartis