Clinical trials: Alcoholic Intoxication
Alcohol Use Disorder
A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
This study will determine the maximum tolerated dose (MTD) of arbaclofen placarbil (AP) in the treatment of subjects with Alcohol Use Disorder (AUD). For every two subjects receiving AP, one subject will receive placebo.
- Trial name
- NCT02511886
- Testing
- Arbaclofen Placarbil
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indivior Inc.
Alcoholic Intoxication, Wounds and Injuries
Phone Intervention for Alcohol (ETOH) Use in Emergency Department Motor Vehicle Crash (ED MVC) Patients
The purpose of this study is to determine if a brief counseling intervention, delivered by telephone, is more effective than standard ED care, to reduce future alcohol related injuries and alcohol related negative consequences…
- Trial name
- DIAL (NCT00457548)
- Testing
- Brief Telephone Counseling for risky aclohol use
- Sponsor
- Rhode Island Hospital
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Abuse, Alcohol Drinking
Tracking Mood: The Effects of Daily Mood Tracking VAS on Alcohol Consumption in Adult Heavy Drinkers
The study aims to investigate the effects that mood tracking may have on the alcohol consumption of adults who consume more than 20 UK units of alcohol per week, classifying as high-risk drinkers.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcohol Use Disorder, Alcohol Dependence
- Trial name
- NCT06419647
- Testing
- Intervention
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ilona Myllyniemi
Alcohol Drinking, Alcohol Use Disorder
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study
In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT06687525
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Psychological Stress, Alcohol Intoxication
Stress-motivated Alcohol Use as a Value-based Decision-making Process
The goal of this experimental study is to improve our understanding of the effects of stress on the decision to consume (more) alcohol in regular drinkers.
- Trial name
- NCT06264791
- Testing
- Stress, Alcohol
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cannabis Intoxication, Alcohol Intoxication
Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment
This human laboratory study will use cognitive, behavioral, and subjective measures to characterize impairment associated with co-use of alcohol and vaporized cannabis.
- Trial name
- NCT06293040
- Testing
- Cannabis, Alcohol
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol Consumption, Alcohol
Rapid BAC Reduction with Nutraceutical Blend Study
Study Title: Nutritional Supplement to Rapidly Decrease Blood Alcohol Concentration (BAC): Safety and Efficacy Study Design: Double-blind, randomized, placebo-controlled clinical trial Objective: Evaluate safety and efficacy of a…
- Conditions
- Alcohol Consumption, Alcohol, Hangover Symptoms, NAC, Veisalgia
- Trial name
- NCT06722898
- Testing
- Supplement
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Methanol Poisoning
Methanol Poisoning
This study addresses methyl alcohol intoxications with profound acidosis requiring intensive care treatment. The goal is to contribute both to the improvement of diagnosis and follow-up processes and to the development of…
- Trial name
- NCT06931587
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kartal City Hospital
Alcohol Drinking, Alcohol Intoxication
Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking
Alcohol use disorder (AUD) impacts millions of Americans and is associated with significant behavioral, social, economic, medical, and neurobiological dysfunction, yet current behavioral treatments for AUD are only modestly…
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcoholism
- Trial name
- MBItDCS (NCT02861807)
- Testing
- Brain stimulation with mindfulness-based relapse prevention
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Alcoholic Intoxication, Chronic
Does the Threat of an Aversive Reaction Affect Craving of Alcohol During Cue Exposure in Alcohol Dependent Patients?
To evaluate the effect of the threat of an aversive reaction on the response during alcohol cue exposure in alcohol dependent patients : (1) the subjective response (craving) and (2) the physiological response (heart rate and…
- Trial name
- NCT00372749
- Testing
- Aversive reaction during alcohol cue exposure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Volunteers Repeated Drug Poisoning, Alcoholic
Repeated Voluntary Drug Intoxication (IMVr): Characterization of a New Addictive Behavior by Clinical Phenotyping and Functional Imaging
France is one of the European countries with the highest rate of death by suicide, more than 10 400 deaths each year, about 16 people out of 100 000.
- Conditions
- Volunteers Repeated Drug Poisoning, Alcoholic, Volunteers
- Trial name
- Phenot IMVr (NCT02889042)
- Testing
- MRI and biological assessment
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Transportation Accidents, Drunk Driving
Design and Implementation of a Drunk Driving Detection System
To analyse driving behavior of individuals under the influence of alcohol using a validated research driving simulator. Based on the driving variables provided by the simulator the investigators aim at establishing algorithms…
- Conditions
- Transportation Accidents, Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT04980846)
- Testing
- Driving under the influence of alcohol with a driving simulator
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Use Disorder, Alcohol Use, Unspecified
Drinking, Acetate, and Stress
The purpose of this study is to learn how drinking alcohol affects how people experience stress and how that is affected by the body's chemistry.
- Conditions
- Alcohol Use Disorder, Alcohol Use, Unspecified, Heavy Drinker, Alcohol Use Disorder, Moderate, in Sustained Remission
- Trial name
- NCT06584448
- Testing
- Deuterium Metabolic Imaging with deuterated acetate tracer
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Consumption, Alcoholic Intoxication
Naltrexone for Heavy Drinking in Young Adults
In this study, 140 heavy drinking young adults (aged 18-25) will be provided with brief counseling and either naltrexone, a medication that is FDA-approved for the treatment of alcohol dependence, or placebo over the course of 8…
- Conditions
- Alcohol Consumption, Alcoholic Intoxication, Alcoholism, Alcohol-induced Disorders
- Trial name
- NCT00568958
- Testing
- BASICS counseling, naltrexone
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Cannabis Use, Alcohol Use, Unspecified
Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)
This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as…
- Trial name
- NCT06259916
- Testing
- Alcohol, Cannabis
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Alcohol Concentration Values, Alcohol Intoxication
Manipulation of Breath Alcohol Tests: Can Specific Techniques Alter Blood Alcohol Concentration Readings?
This is a prospective cohort study. The investigators will enroll 50 healthy volunteers. In a safe environment and after signing informed consent, each participant will consume a standardized alcoholic beverage.
- Trial name
- NCT02580318
- Testing
- breathalyzer
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Alcohol Use Disorder, Blood Alcohol Content
Self-estimates and Objective Blood Alcohol Concentration in Emergency Department
Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC).
- Trial name
- SEOBACED (NCT03998397)
- Testing
- blood alcohol concentration withdrawal
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Alcoholic Intoxication, Automobile Accident
Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers
The new recreational marijuana markets are contributing to polysubstance-impaired driving and other harms, especially when marijuana is used in combination with alcohol, by selling marijuana to obviously-intoxicated customers.
- Conditions
- Alcoholic Intoxication, Automobile Accident, Cannabis
- Trial name
- NCT06235632
- Testing
- Policy and Training Intervention, Usual and Customary Policy and Training (UC-PT) (Control) Condition
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Klein Buendel, Inc.
Intoxication Alcohol
Stop-Service to Obviously-Impaired Patrons
The Responsible Retailing Forum ("RRF") seeks to develop a new intervention, Stop Service to Obviously- Impaired Patrons ("S-STOP"), to reduce the incidence and harm associated with overservice of alcohol.
- Trial name
- SSTOP (NCT03608787)
- Testing
- S-STOP
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- RRF Field Services LLC