Clinical trials: Alcohol Use Disorders
Marijuana Use, Marijuana Dependence
Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use
The overarching goal of this online study is to compare the efficacy of six (weekly) sessions of Domain-Specific Episodic Future Thinking (DS-EFT) relative an active control condition on improving the ability to value future…
- Conditions
- Marijuana Use, Marijuana Dependence, Tobacco Use, Alcohol Use, Unspecified
- Trial name
- NCT05324813
- Testing
- Domain-Specific Episodic Future Thinking
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Michael Sofis
Tobacco Use Disorder
Tobacco Cessation Field Study for Adults in Recovery - 1
The project's aim is to provide a targeted, computer-administered intervention to facilitate tobacco cessation for clients in alcohol treatment.
- Trial name
- NCT00109460
- Testing
- Tobacco Use Disorder
- Where
- 7 sites in United States
- Volunteers
- 203 people
- Sponsor
- Inflexxion, Inc.
Alcohol Use Disorder (AUD)
Sleep and Emotional Reactivity in Alcohol Use Disorder
Alcohol use disorder (AUD) is a multifaceted, chronic relapsing disorder suffered by millions of men and women in the United States.
- Trial name
- SEAS (NCT04979507)
- Testing
- Uninterrupted sleep followed by functional neuroimaging.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SRI International
Alcohol Use Disorder
Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)
The goal of this clinical trial is to investigate treatment with psilocybin and psychotherapy for the treatment of people with Alcohol Use Disorder (AUD).
- Trial name
- NCT05646303
- Testing
- Psilocybin
- Where
- 12 sites in Canada, Finland
- Volunteers
- 128 people
- Sponsor
- Clairvoyant Therapeutics
Alcohol Use Disorder
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
The primary objective of this study is to find the tolerable dose and characterize the safety and pharmacokinetics/ pharmacodynamics (PK/PD) of single and repeated dose of CMND-100 in Healthy Volunteers (HV) and Subjects with…
- Trial name
- NCT05913752
- Testing
- CMND-100
- Where
- 4 sites in United States, Israel
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clearmind Medicine Inc.
Burnout, Student, Alcohol; Harmful Use
Summative Assessment of the BurntOut 3D Simulation With Medical Students
Burnout is a common problem for medical students and is associated with stress-related health problems and also potentially affects the quality of care delivered to their patients.
- Conditions
- Burnout, Student, Alcohol; Harmful Use, Quality of Life, Depression
- Trial name
- NCT04494633
- Testing
- Clinical Encounters Medical School 3D Simulation
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinical Tools, Inc.
Alcohol Use Disorder
Preliminary Analysis of the Soberlink Alcohol Breath Analyzer System's (SABA) Clinical Utility During Aftercare
This is an exempt, retrospective study of a limited set of information obtained from patients' medical records at 10 to 12 substance abuse treatment programs combined with alcohol breath analyzer results during up to 3 years of…
- Trial name
- NCT02544581
- Testing
- Soberlink combined with aftercare services
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- SoberLink, LLC
Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD)
Smartphone-Based Intervention for Sleep Disturbance in Individuals Recovering From Alcohol Use Disorder
In order to assess the efficacy of the rhythm stabilization component of Health Rhythms' product in addressing sleep problems, investigators will recruit 128 outpatients over the age of 18, who are in early recovery (at least 2…
- Conditions
- Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD), Sleep Disorder, Sleep Disturbance
- Trial name
- NCT06108115
- Testing
- CueToSleep (Full Intervention Package)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- HealthRhythms, Inc.
Alcohol Use Disorder
Study of Sunobinop on Craving in Alcohol Use Disorder
The purpose of this study is to evaluate the efficacy of sunobinop compared to placebo on alcohol craving in subjects with moderate to severe alcohol use disorder and these subjects are seeking treatment.
- Trial name
- NCT06545929
- Testing
- Sunobinop
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Knoa Pharma LLC
Alcohol Use Disorder
Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder
The primary goal of this Phase 1b clinical trial is to evaluate the effects of a novel TAAR1 receptor partial agonist (NTX-2001) in adults with Alcohol Use Disorder (AUD).
- Trial name
- NCT07520292
- Testing
- NTX-2001
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Newleos Therapeutics, Inc.
Motivational Interviewing, Alcohol Use Disorder
ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing
This multi-stage study includes qualitative interviews, usability research, and a randomized training study of technology implementation in a real-world clinical setting.
- Trial name
- NCT05479890
- Testing
- ClientBot
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Lyssn.io, Inc.
Alcohol Use Disorder (AUD), Substance Use Disorders
Pilot: Digital Therapeutic vs Education for the Management of Problematic Substance Use
Prior to launching a randomized controlled trial, this pilot study will investigate the feasibility and acceptability of the administration of a diagnostic interview and collection of a biomarker test, as well as engagement and…
- Trial name
- NCT04974645
- Testing
- W-SUDs, Digitally-delivered Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Woebot Health
Alcohol Use Disorder
Treatment Parameters for the Empower Neuromodulation System (ENS)
The subject will be administered a treatment at a treatment location and then be asked if he/she believes it is the active treatment, sham treatment, or does not know.
- Trial name
- AUD1 (NCT03807544)
- Testing
- TENS
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Theranova, L.L.C.
Substance Use Disorders, Alcohol Use Disorder
W-SUDs for COVID-19
The purpose of this study is to test the efficacy of a substance use disorder intervention delivered via a mobile application in an adult population during the COVID-19 pandemic.
- Trial name
- NCT04460027
- Testing
- Woebot Substance Use Disorder
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Woebot Health
Alcohol Dependence
Efficacy of Nalmefene in Patients With Alcohol Dependence
The purpose of the study is to evaluate the efficacy, safety and tolerability of nalmefene in the treatment of alcohol dependence.
- Trial name
- ESENSE1 (NCT00811720)
- Testing
- Nalmefene
- Where
- 39 sites in Austria, Finland and 2 more
- Volunteers
- 598 people
- Sponsor
- H. Lundbeck A/S
Alcohol Drinking, Alcohol Intoxication
Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms
The aim of this open-label, randomized, crossover, comparative pilot study is to assess efficacy and safety of the dietary food supplement ALCOFILTRUM in healthy volunteers who consume alcohol.
- Trial name
- NCT05757089
- Testing
- ALCOFILTRUM
- Where
- Belarus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AVVA Pharmaceuticals Ltd.
Alcohol Use Disorder
A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
This study will determine the maximum tolerated dose (MTD) of arbaclofen placarbil (AP) in the treatment of subjects with Alcohol Use Disorder (AUD). For every two subjects receiving AP, one subject will receive placebo.
- Trial name
- NCT02511886
- Testing
- Arbaclofen Placarbil
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indivior Inc.
AUD
Phase II Clinical Study on the Efficacy and Safety of Naltrexone Implant in Patients With Alcohol Use Disorder
This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial. The study plans to enroll 210 adult patients with alcohol use disorder.
- Trial name
- NCT07333638
- Testing
- low-dose group (naltrexone implant 0.9 g + general supportive psychological counseling), high-dose group (naltrexone implant 1.5 g + general supportive psychological counseling)
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Shenzhen Sciencare Medical Industries Co., Ltd.
Alcohol Dependence
Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence
The purpose of the study is long-term safety, tolerability and efficacy of nalmefene in patients with alcohol dependence.
- Trial name
- SENSE (NCT00811941)
- Testing
- Nalmefene
- Where
- 60 sites in Czechia, Estonia and 8 more
- Volunteers
- 665 people
- Sponsor
- H. Lundbeck A/S
Alcohol Use Disorder
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will last approximately 56 weeks.
- Trial name
- RENEW-ALC-1 (NCT07219966)
- Testing
- LY3537031
- Where
- 117 sites in United States, Belgium and 6 more
- Volunteers
- 1,100 people
- Sponsor
- Eli Lilly and Company