Clinical trials: Alcohol Use
Alcohol Drinking, Anxiety Disorders
Retraining Attention to Treat Alcohol Dependence and Social Anxiety
The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence.
- Trial name
- AMP (NCT01886716)
- Testing
- Anxiety Attention Training, Alcohol Attention Training, Control Training
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Cincinnati
Substance Use
Effects of a Peer-led Educational Intervention Based on Theory of Planned Behavior on Substance Use Intentions and Behaviors Among Secondary School Students of Dessie and Kombolcha Town, Northeast Ethiopia.
This study aims to measure the effects of a per-led educational intervention based on theory of planned behavior to reduce tobacco, alcohol and khat use and intention to use among secondary school students over 3-months of…
- Trial name
- NCT04863625
- Testing
- a peer-led educational intervention based on theory of planned behavior on substance use intentions and behaviors
- Where
- Ethiopia
- Volunteers
- 1,496 people
- Sponsor
- Wollo University
Binge Drinking
Alcohol Consumption Relation With Nutritional Knowledge and Body Weight
The increase of overweight and obesity in young Italian people, nowadays showed by several epidemiological data, has been related to the misuse of alcohol and to a lack in nutritional knowledge.
- Trial name
- NCT02336204
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Alcohol Drinking
Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms
This study will help to determine whether the medication, topiramate, reduces alcohol use among adolescents with alcohol dependence.
- Trial name
- IMPACT (NCT01641445)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brown University
Anxiety Depression, Alcohol Abuse
CBD Oil for Reducing Emotional Impact of COVID-19
Our purpose is to conduct a 4-arm placebo-controlled clinical trial to investigate the relative clinical efficacy of 300 mg. of pure hemp-derived CBD isolate, 300 mg. of full spectrum CBD oil, 300 mg.
- Conditions
- Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger
- Trial name
- CBDOIL (NCT04603781)
- Testing
- CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Bipolar Disorder, Alcohol Abuse
Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults
The purpose of this research study is to study the effects (both good and bad) of combining quetiapine and topiramate for treating symptoms of bipolar mania (an illness with periods of elation, excessive excitement, irritability…
- Trial name
- NCT00550394
- Testing
- Quetiapine and Topiramate
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Cincinnati
Alcohol Drinking
Do Treatments for Smoking Cessation Affect Alcohol Drinking?
The purpose of this study is to examine the effect of smoking cessation medications on alcohol drinking. Effect of 2mg/day, 1mg/day, placebo varenicline was evaluated.
- Trial name
- NCT00580645
- Testing
- varenicline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Alcohol Abuse, Cannabis Abuse
Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
- Trial name
- NCT00108407
- Testing
- Integrated Cognitive Behavioral Therapy, Twelve Step Facilitation Therapy
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Alcohol Drinking, Cannabis Use
Mindsets and the Effectiveness of a Brief Intervention - Replication
Brief Interventions (BI) based on Motivational Interviewing are effective in reducing alcohol use. In this study, the investigators test the hypothesis that mindsets increase the positive effects of BI among a student sample of…
- Trial name
- MindsetBI-R (NCT05167097)
- Testing
- ASSIST-linked Brief Intervention, Mindset Intervention
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- University of Konstanz
Alcohol Dependence
Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence
The purpose of the study is long-term safety, tolerability and efficacy of nalmefene in patients with alcohol dependence.
- Trial name
- SENSE (NCT00811941)
- Testing
- Nalmefene
- Where
- 60 sites in Czechia, Estonia and 8 more
- Volunteers
- 665 people
- Sponsor
- H. Lundbeck A/S
Alcohol Use Disorder, Alcoholic Hepatitis
Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH
Given the severe consequences of alcohol relapse following liver transplantation for alcoholic hepatitis (AH-LT), it is critical to accurately identify alcohol use and implement alcohol interventions early in the post-transplant…
- Trial name
- NCT03845205
- Testing
- Integrated AUD Treatment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Healthy Controls, Alcohol Use Disorder
Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II
The proposed study will investigate the effects of intranasal oxytocin administration on neural activity associated with social and non-social motivation.
- Trial name
- NCT02652195
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Utah
Alcohol Use, Unspecified
Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School
The purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes…
- Trial name
- NCT06191861
- Testing
- Most hoped for future self, Most feared future self, Control (trip to zoo)
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Washington
Substance Use Disorder, Alcohol Use Disorder
Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP
Background: People who will participate in research studies need to undergo proper screening, evaluation, and assessment (SEA). SEA helps keep those who participate in studies safe. It also helps ensure accurate study results.
- Trial name
- NCT06552741
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Dependence
Study of Acamprosate to Prevent Alcohol Relapse in Criminal Justice Supervisees
The purpose of this study is to test how tolerable and effective acamprosate is when used to prevent alcohol relapse in criminal justice supervisees (those on probation, parole, or in drug court).
- Trial name
- NCT00249379
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Alcohol Use Disorder
Image-guided, Robot Navigated Transcranial Magnetic Stimulation (IR-TMS) for Alcohol Use Disorder (AUD)
This study is testing a new treatment called IR-TMS (image-guided, robot navigated transcranial magnetic stimulation) to see if it can help people who drink too much alcohol to reduce the amount they drink.
- Trial name
- NCT06648642
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Depression, Anxiety
CAMH PARTNERs Integrated Care Study
This research study will evaluate an integrated care model of telephone-based, computer-aided care management using a new role of Mental Health Technician and specialized software to support primary care providers in providing…
- Conditions
- Depression, Anxiety, Alcohol Drinking
- Trial name
- PARTNERs (NCT02345122)
- Testing
- Intervention: Mental Health Technician, Enhanced Usual Care
- Where
- Canada
- Volunteers
- 635 people
- Sponsor
- Centre for Addiction and Mental Health
Sepsis, Alcoholism
Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis
Patients with alcohol use disorders are often cared for in the intensive care unit (ICU). We estimate that close to half of the patients we care for in our ICU have alcohol use disorders.
- Trial name
- NCT00615862
- Testing
- Observational study; no interventions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Alcohol Drinking
The Influence of Water and Salt Intake on Copeptin Levels During Moderate Alcohol Consumption
The main interest of this study is to investigate the influence of moderate alcohol consumption (beer) on salt-water homeostasis.
- Trial name
- NCT03883503
- Testing
- Beer 5%o, Beer 8.5%o and water, Beer 8.5%o and stock
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Alcohol Use Disorder (AUD), Alcoholism
Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
This study looked at whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation treatment, could help adults with alcohol use disorder when added to their usual treatment.
- Trial name
- NCT07755046
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Ting-Gang Chang