Clinical trials: Alcohol Use
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Alcohol Use, Drug Use
Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care
Screening youth in the primary care setting is one way to identify adolescents who may be at-risk for future alcohol problems. The current study tests the new NIAAA screening guide questions, which ask about friend and adolescent…
- Trial name
- NCT01797835
- Testing
- CHAT brief MI intervention, usual care
- Where
- 2 sites in United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Use Disorder
Naltrexone for Individuals of East Asian Descent
This study will elucidate the pharmacogenetic effects of the Asn40Asp SNP of the OPRM1 gene on biobehavioral and neural markers of response to naltrexone in individuals of East Asian descent, an ethnic group most likely to…
- Trial name
- NCT02026011
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, Los Angeles
Adolescent Alcohol Use
Strong African American Families STEPS Project
The most common approach to preventing alcohol use involves providing a well-designed program in preadolescence just prior to or upon entering middle school.
- Trial name
- SAAF-STEPS (NCT03590132)
- Testing
- Strong African American Families Program, Strong African American Families--Teen Program
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Alcohol Use Disorder
Inpatient Alcohol Detox & Psychotherapy
The aim of the study is to evaluate effectiveness of inpatient detoxification and psycho-therapeutic support, measured in terms of readiness to change and abstinence maintenance.
- Trial name
- NCT03988478
- Testing
- Detoxification & psychotherapeutic support
- Volunteers
- 109 people
- Sponsor
- Tribhuvan University, Nepal
Alcohol; Harmful Use
Testing A Couple-based Program for Alcohol Risk Reduction in the National Guard
The purpose of this project is to develop and test indicated prevention intervention to harness support and health promoting endeavors to address use of alcohol to cope with reintegration challenges in Massachusetts National…
- Trial name
- GF_CARE (NCT03589508)
- Testing
- In-person sessions: ABCP_P, Video conference sessions: ABCP_T
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Massachusetts, Worcester
Alcohol Use Disorder, Contingency Management
CM Treatment for Alcohol Dependence Using New Technology
Contingency management (CM) is highly efficacious for reducing substance use, and recent data suggest that reinforcing attendance at treatment can significantly improve treatment outcomes.
- Trial name
- NCT02143037
- Testing
- prize contingency management for attending treatment, usual care
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- UConn Health
Posttraumatic Stress Disorder, Substance Use Disorder
Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder
This study compares Creating Change, a new past-focused behavioral therapy for posttraumatic stress disorder (PTSD)/substance use disorder (SUD), to Seeking Safety, an evidence-based present-focused behavioral therapy for…
- Conditions
- Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
- Trial name
- NCT01274741
- Testing
- Creating Change (CC), Seeking Safety (SS)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- VA Boston Healthcare System
Problematic Alcohol Use
Brief Alcohol Interventions With Mobile Phone Applications for University Students: A Randomized Controlled Trial
Objectives: This study evaluates the efficacy of two mobile phone applications, Promillekoll and PartyPlanner among university government members at two universities in Stockholm, Sweden.
- Trial name
- NCT01958398
- Testing
- Promillekoll, PartyPlanner
- Where
- Sweden
- Volunteers
- 4,408 people
- Sponsor
- Karolinska Institutet
Alcohol Use
Text Messaging as a Novel Alcohol Intervention for Community College Students
This project will develop an intervention delivered through text messaging to reduce alcohol consumption and high risk drinking among adults who are enrolled as students in community colleges.
- Trial name
- TMAP (NCT02507115)
- Testing
- TMAP, Mojo Texts
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Alcohol Use Disorders
Mindfulness-Based Relapse Prevention for Alcohol Use Disorders in Remission
We propose to conduct a pilot study that will examine the utility and mechanisms of Mindfulness-Based Relapse Prevention in reducing alcohol consumption, relapse rates, and physiological arousal to stress in adults 21 years of…
- Trial name
- MBRP (NCT02147483)
- Testing
- Mindfulness Based Relapse Prevention, Treatment as usual
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Virginia
Alcohol Use Disorder
Soberlink Within In-Home Addiction Treatment Program
The purpose of this study is to evaluate the impact of use of Soberlink on treatment experience for individuals with alcohol use disorder while enrolled in an In-Home Addiction Treatment program.
- Trial name
- NCT03902171
- Testing
- Soberlink
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- In-Home Addiction Treatment Institute, Inc.
Opioid Use Disorder, Alcohol Use Disorder
Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
The purpose of this study is to learn how best to treat substance use disorders in an HIV clinic setting. Specifically, the purpose of this pilot study is to learn if extended-release naltrexone (XR-NTX) would be a feasible and…
- Trial name
- CHOICES (NCT01908062)
- Testing
- Extended Release Naltrexone, Treatment As usual
- Where
- 2 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Oregon Health and Science University
Alcohol Use Disorders
Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
In comparison to the general population, military personnel and veterans are at increased risk of developing both substance use disorders (SUDs) and post-traumatic stress disorder (PTSD).
- Trial name
- NCT02058251
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Medical University of South Carolina
Tobacco Use, Drug Use
Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention
The study aims to develop tobacco modules to be included in an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) and to determine the feasibility and preliminary efficacy of the updated version of S4E in…
- Conditions
- Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use
- Trial name
- NCT03855410
- Testing
- S4E, Attention-Matched Control Group
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Liver Disease, Alcohol Use Disorder
Nottingham Community Liver Biomarkers Cohort
Deaths due to advanced liver scarring (liver cirrhosis) continue to increase, and liver disease is now the 3rd leading cause of premature death in the United Kingdom.
- Conditions
- Chronic Liver Disease, Alcohol Use Disorder, Type 2 Diabetes, Persistently Elevated ALT
- Trial name
- NCT02037867
- Testing
- Fibrosis Biomarkers
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- University of Nottingham
Alcohol Use Disorder, Inflammation
Minocycline for Alcohol Use Disorder
The objective of this proposal is to advance medication development for alcohol use disorder by examining the efficacy and mechanisms of action of minocycline, a neuroimmune modulator, as a potential treatment.
- Conditions
- Alcohol Use Disorder, Inflammation, Neurocognitive Dysfunction, Craving
- Trial name
- NCT03244592
- Testing
- Minocycline, Sugar pill
- Sponsor
- University of California, Los Angeles
Alcohol; Use, Problem, Marijuana Usage
Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users
This is a pilot study of the feasibility, acceptability, and effectiveness of a brief, one-session intervention for a diverse sample of 44 young adults who report alcohol binge drinking or marijuana use in the past month.
- Trial name
- NCT03801096
- Testing
- Narrative Based Therapuetic Assessment (NbTa), Health Education Control Condition (HE)
- Volunteers
- 44 people
- Sponsor
- University of Houston
Alcohol Use, Alcohol Drinking
Young Adult Naturalistic Alcohol Study (YANAS) Using Smartphone Technology in a Simulated Laboratory Environment
It is important to explore use of technology to reduce drinking. The purpose of this research study is to compare different types of mobile technology for their effects on alcohol drinking and ratings of usability among young…
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- NCT02841735
- Testing
- Smartphone breathalyzer device/app use, BAC estimator app use, Text messaging procedure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Florida
Substance Abuse, Substance Dependence
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
The purpose of this study is to determine whether drug-dependent adults who participate in a dual processing relapse prevention treatment protocol that allows for sensory-based exposure experiences over 10-weeks in outpatient…
- Conditions
- Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use
- Trial name
- NCT01320748
- Testing
- Dual Processing, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Inova Health Care Services