Clinical trials: Alcohol Use
Alcohol Exposed Pregnancy, Unplanned Pregnancy
Optimizing a Digital AEP Risk Intervention With Native Women and Communities
The purpose of Aim 1 of the study is to gather quantitative and qualitative information to inform the development of a digital app tailored for Native American women to help them avoid a pregnancy affected by alcohol.
- Conditions
- Alcohol Exposed Pregnancy, Unplanned Pregnancy, Alcohol Use, Unspecified, Contraception Use
- Trial name
- CARRIINative (NCT06324929)
- Testing
- CARRII Native Rapid Pilot Testing
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Alcoholism, rTMS Stimulation
Effectiveness of High-frequency rTMS in Reducing Alcohol Consumption in Non-abstinent Patients With an Alcohol Use Disorder
The fight against alcoholism is a public health priority. Around 15 million Europeans and 10 million North Americans are alcohol dependent. Worldwide, 1 death out of 25 is thought to be attributed to alcohol.
- Trial name
- ALCOSTIM (NCT04773691)
- Testing
- Active rTMS, Questionnaires, Breathalyzer
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
HIV Infection
Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use
The overall objective is to determine the influence of timing of ART initiation and alcohol consumption on HIV disease course. ART initiation immediately after HIV infection largely results in smaller HIV reservoir and lower…
- Trial name
- MERLIN (NCT02744040)
- Testing
- ART initiation at time of HIV diagnosis, ART at 24 weeks
- Where
- Peru
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Alcohol Use
Impaired Risk Awareness During Intoxication in DUI Offenders
This study aims to test the efficacy of experiential-based training to increase DUI offenders' perceptions or risk associated with alcohol use.
- Trial name
- NCT05247788
- Testing
- Blood alcohol concentration (BAC) discrimination training, Performance feedback training, Blood alcohol concentration (BAC) discrimination training for controls
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mark Fillmore
Alcohol Use Disorder
Financially Sustainable Remote Treatment for Alcohol Abuse: Feasibility
Directly reinforcing abstinence from alcohol with monetary incentives is an effective treatment for alcohol dependence, but barriers in obtaining frequent, verified biochemical measures of abstinence limit the dissemination of…
- Trial name
- NCT04182022
- Testing
- Contingency management: Contingent incentives, Contingency management: Noncontingent incentives
- Volunteers
- 92 people
- Sponsor
- Virginia Polytechnic Institute and State University
Alcohol Use Disorder
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
This is a double-blind, randomized, placebo-controlled Phase 2 mechanistic clinical trial designed to evaluate the therapeutic neural mechanisms of psilocybin in patients with alcohol use disorder (AUD), and to determine whether…
- Trial name
- NCT06349083
- Testing
- Psilocybin, Supportive therapy sessions
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Alcohol Use Disorder
Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Twenty participants, age 18 or older, who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for moderate to severe Alcohol Use Disorder will be randomized to open-label psilocybin (25 mg) therapy with…
- Trial name
- NCT04410913
- Testing
- Psilocybin plus Visual Healing Set and Setting, Psilocybin plus Standard Set and Setting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Keith Heinzerling
Post Traumatic Stress Disorder, Alcohol Use Disorder
Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
This is a double-blind, 2-group randomized controlled trial evaluating the effects of topiramate versus placebo in patients with comorbid PTSD and moderate-to-severe AUD.
- Trial name
- NCT03667846
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Alcohol Drinking, Binge Drinking
Alerta Alcohol. Web-based Computer-tailored Intervention for Binge-drinking Prevention in Spanish Adolescents
This study consists in the the design, implementation, and evaluation of the first web-based computer tailored intervention program aimed at the prevention of binge drinking in Spanish adolescents (Alerta Alcohol).
- Conditions
- Alcohol Drinking, Binge Drinking, Adolescent Behavior
- Trial name
- NCT03288896
- Testing
- Alerta Alcohol
- Where
- Spain
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- University of Seville
Alcohol Use Disorder
Ketamine for the Treatment for Alcohol Use Disorder in the ED
The investigators' approach is to conduct a pilot double-blind, placebo-controlled randomized clinical trial with individuals with alcohol use disorder (AUD) seeking inpatient alcohol detoxification in the emergency department…
- Trial name
- NCT05661669
- Testing
- Ketamine, Saline
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Alcohol Dependence
The Effects of Mirtazapine Versus Placebo on Alcohol Consumption in Male Alcohol High Consumers
The purpose of this study is to study the effects of 8 weeks of treatment with mirtazapine on alcohol consumption in alcohol high consuming men.
- Trial name
- NCT00874003
- Testing
- mirtazapine
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Sahlgrenska University Hospital
Insomnia, Alcohol; Harmful Use
The Insomnia Treatment and Problems Study for Veterans
This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes.
- Trial name
- iTAP-V (NCT03804788)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygeine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Heavy Drinking, Alcohol Abuse
Effects of Acute Exercise on Various Parameters in Individuals With Alcohol Use Disorders
The purpose of this research is to examine the effects of exercise of different intensities on psychological, physiological, biochemical, physiological and alcohol-related parameters in individuals with alcohol use disorders…
- Conditions
- Heavy Drinking, Alcohol Abuse, Alcohol Dependence, Alcohol Use Disorder
- Trial name
- NCT02664727
- Testing
- The effects of acute exercise in heavy drinkers, The effects of acute exercise in alcoholic patients
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Depression, Anxiety
Systematic Screening for Comorbid Psychological Conditions in Cardiac ACSC Patients With Multimorbidity in the ED
EMASPOT assesses the prevalence and impact of mental health conditions in multimorbid emergency patients with cardiac ACSC on transsectoral utilisation of health care services.
- Conditions
- Depression, Anxiety, Somatoform Disorders, Alcohol Abuse
- Trial name
- EMASPOT (NCT03188861)
- Where
- Germany
- Volunteers
- 650 people
- Sponsor
- Charite University, Berlin, Germany
Alcohol Use Disorder
Dexamethasone to Target Stress and Immune System Mechanisms Underlying Alcohol Craving
This is a double-blind, placebo-controlled, proof of concept laboratory study to recruit N=70 (35 Males / 35 Females) non-treatment seeking, heavy drinkers with alcohol use disorder (AUD).
- Trial name
- NCT05305404
- Testing
- Dexamethasone Oral
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Stony Brook University
Alcohol-associated Hepatitis
Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial
This is a multicenter, randomized, double-blinded, placebo-controlled trial focused on the treatment of severe alcohol-associated hepatitis (sAH) and alcohol use disorder (AUD).
- Trial name
- ITAALD (NCT07060638)
- Testing
- IL-22, Prednisone, Acamprosate
- Where
- 6 sites in United States
- Volunteers
- 216 people
- Sponsor
- Samer Gawrieh
Bipolar Disorder, Alcohol Drinking
Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Alcohol use disorders (AUDs) affect up to 60% of individuals with bipolar disorder during their lifetime-a rate 3 to 5 times higher than what occurs in the general population.
- Conditions
- Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
- Trial name
- BACS (NCT04063384)
- Testing
- alcohol beverage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Dependence, Alcohol Interaction
Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol
The purpose of the clinical study is to compare pharmacodynamic and safety endpoints following an alcohol challenge prior to and concurrent with PT150 (study drug) treatment.
- Trial name
- NCT03548714
- Testing
- PT150, Beverage
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Pop Test Oncology LLC
Binge Drinking, Heavy Drinking
Brief ROC Training Effects on Alcohol Drinking
The goal of the proposed study is to examine whether a single session of training in regulation of craving (ROC-T) affects alcohol drinking.
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Trial name
- NCT03928626
- Testing
- Regulation of craving, Control (NO REGULATION)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypertension, Adult
Systematic Investigation of Blacks With Stroke - GENOMICS
The overall goal of SIBS-GENOMICS is to utilize the best available contextual data on stroke in Africa to develop \& validate stroke risk estimation models, translate the best model into a mobile phone app and conduct a…
- Conditions
- Hypertension, Adult, Dyslipidemias, Physical Inactivity
- Trial name
- SIBSGENOMICS (NCT05619406)
- Testing
- Riskometer Application, Routine Clinic Therapy
- Where
- 3 sites in Ghana, Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College Hospital, Ibadan