Clinical trials: Alcohol Use
Delirium, Agitated Behavior
Trial of Safety Nets In Hospitalized Patients
This study compared standard hospital restraints to a newer safety net restraint system to compare them for acceptability, tolerance, duration of restrain, length of stay in the hospital, and satisfaction of MD, nurse, and…
- Conditions
- Delirium, Agitated Behavior, Alcohol Withdrawl, Acute Confusional State
- Trial name
- NCT00409370
- Testing
- SOMA safe enclosure
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Griffin Hospital
Alcohol Use Disorder
Severe Alcohol-use Disorder: a tDCS and Response Inhibition Training Intervention
Most severe forms of alcohol-use disorder are thought to reflect an abnormal interplay between two neural systems: an overly active impulsive one driven by immediate rewards prospects and a weak reflective one, tuned on long-term…
- Trial name
- ALCOSTIM (NCT03447054)
- Testing
- Combined TDCS active and ICT active, Combined TDCS active and ICT inactive
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Brugmann University Hospital
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Liver Transplant Recipient, Alcohol Use Disorders (AUD)
Intervention for Alcohol Use Disorder Recovery After Liver Transplantation
The goal of this clinical trial is to learn if it is feasible and acceptable to use a recovery coach and an online sober active community to help with alcohol use disorder after liver transplant.
- Trial name
- ILTARP (NCT07214259)
- Testing
- Online Sober Active Community, Recovery coach
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Leigh Anne Dageforde
Alcohol Use Disorder
Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder
Background: Chronic heavy drinking can cause alcohol use disorder (AUD). AUD changes how the brain works. People with AUD may drink compulsively or feel like they cannot control their alcohol use.
- Trial name
- NCT06269627
- Testing
- Acamprosate calcium
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Energy Drinks, Alcohol Drinking
The Effect of Energy Drink Consumption on Alcohol-Substance Use and It's Relationship With Impulsivity In University Students
The objective of this study is to investigate the prevalence of energy drink, alcohol and substance use among university students; to explore whether there is a relationship between energy drink consumption and alcohol-substance…
- Conditions
- Energy Drinks, Alcohol Drinking, Substance Use, University Students
- Trial name
- NCT02593617
- Testing
- Addiction Profile Index, Alcohol Use Disorders Identification Test, Barratt Impulsiveness Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 2,623 people
- Sponsor
- Mustafakemalpasa State Hospital
Alcohol Drinking
Implementing Alcohol Misuse SBIRT in a National Cohort of Pediatric Trauma Centers
The goal of this study is to conduct a fully powered Type III hybrid effectiveness-implementation trial to test the effectiveness of a comprehensive implementation strategy in increasing the implementation of SBIRT for alcohol…
- Trial name
- IAMSBIRT (NCT03297060)
- Testing
- SSL Implementation Strategy
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- Rhode Island Hospital
Alcohol Dependence, Bipolar Disorder
Open Label Trial of Acamprosate in Bipolar Alcoholics
The purpose of this study is to determine whether acamprosate (Campral) is safe and effective in treating alcohol dependence in individuals with bipolar disorder.
- Trial name
- NCT00330486
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Medical University of South Carolina
Alcohol Abuse, Nervous System
A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment
The study primary end point is the decrease in the number of monthly heavy drinking days (HDD) (≥ 60 g/day in men and ≥ 40 g/d in women) from baseline to the end of the double blind Randomized Treatment (RT).
- Trial name
- PoC Alcohol (NCT02800083)
- Testing
- Pitolisant (BF2.649)
- Sponsor
- Bioprojet
Bulimia Nervosa, Alcohol Use Disorders
Examining Common Substrates of Eating and Alcohol Use Disorders
A substantial percentage of individuals with bulimia nervosa (BN) also meet criteria for a co-occurring substance use disorder, such as alcohol abuse or dependence; however, research examining this sub-group of patients with BN…
- Trial name
- NCT01172210
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Alcohol Use Disorder (AUD), Attentional Bias
Attentional Control Training for Treating Alcohol Use Disorder
Background: There is consistent evidence that community and clinical samples of individuals with an alcohol use disorder (AUD) have attentional biases toward alcohol cues.
- Trial name
- NCT05102942
- Testing
- Attentional Control Training Program
- Where
- Denmark
- Volunteers
- 268 people
- Sponsor
- University of Southern Denmark
Alcohol Use Disorder, Mild Traumatic Brain Injury
Pilot rTMS for AUD+mTBI
This is a pilot randomized controlled trial (RCT) for Veteran participants with alcohol use disorder co-occurring with mild traumatic brain injury and/or post-traumatic stress disorder.
- Conditions
- Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
- Trial name
- TMS_AUD+mTBI (NCT03995173)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Neural Mechanisms of Disulfiram Effects
This study combines functional MRI with medication treatment in order to understand the neural mechanisms by which disulfiram, a currently approved medication for alcohol use disorder, changes behavior.
- Trial name
- NCT02735577
- Testing
- Disulfiram
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV, Physical Inactivity
Physical Activity for PLWH and Unhealthy Drinking
Brief Summary: Alcohol use disorder (AUD) is a significant and costly public health problem that affects one-third of the U.S. population in their lifetime.
- Conditions
- HIV, Physical Inactivity, Unhealthy Alcohol Use
- Trial name
- NCT05505942
- Testing
- LPA Sessions, Fitbit Only
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Boston University
Alcohol Consumption, Anxiety
Motivational and Cognitive Intervention for College Drinkers
In the proposed project the investigators will develop and test a novel brief intervention targeting college students who drink heavily to cope with anxiety and depression, a behavior that increases risk for the development of…
- Conditions
- Alcohol Consumption, Anxiety, Depression
- Trial name
- MCID (NCT01204229)
- Testing
- Motivational and Cognitive Intervention for Drinkers (MCID), Brief Motivational Intervention (BMI)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Alcohol Drinking, HIV
Reducing Hazardous Alcohol Use & Human Immunodeficiency Virus (HIV) Viral Load
The purpose of this study is to compare the effectiveness of two interventions [a Brief Intervention (BI) and a Motivational Enhancement Therapy+Cognitive Behavioral Therapy (MET+CBT) Intervention], against each other and with an…
- Trial name
- REDART (NCT02720237)
- Testing
- Brief Intervention, Motivational Enhancement Therapy (MET) Intervention, Cognitive Behavioral Therapy (CBT) Intervention
- Where
- Vietnam
- Volunteers
- 441 people
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease, Non-significant Coronary Artery Disease
TweeSteden Mild Stenosis Study
Psychosocial factors have been found to be associated with an increased risk for coronary artery disease incidence, progression and worse clinical outcomes.
- Conditions
- Coronary Artery Disease, Non-significant Coronary Artery Disease, Mild Stenosis, Vascular Irregularities
- Trial name
- TWIST (NCT01788241)
- Where
- Netherlands
- Volunteers
- 547 people
- Sponsor
- Tilburg University
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder, HIV-infection/Aids
Development of an Intervention to Reduce Heavy Drinking and Improve HIV Care Engagement Among Fisherfolk in Uganda
Fisherfolk are a high risk population for HIV and are prioritized to receive antiretroviral treatment (ART) in Uganda, but risky alcohol use among fisherfolk is a barrier to HIV care engagement; multilevel factors influence…
- Trial name
- NCT03919695
- Testing
- Kisoboka: Behavioral and Structural Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 160 people
- Sponsor
- San Diego State University