Clinical trials: Alcohol Misuse
Substance Use, Substance Abuse
Data-driven Identification for Substance Misuse
The investigators propose to develop an open-source, publicly available machine learning model that health systems could download and apply to their electronic health record data marts to screen for substance misuse in their…
- Conditions
- Substance Use, Substance Abuse, Substance-Related Disorders
- Trial name
- NCT03833804
- Testing
- Processing of clinical notes in the EHR data collected during routine care
- Where
- United States
- Volunteers
- 64,996 people
- Sponsor
- University of Wisconsin, Madison
Alcohol Use Disorder
Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention to Reduce Alcohol Misuse in an Emergency Department
This project focuses on patients in AED. Objectives of this project are: 1. To examine the factors associated with alcohol drinking and alcohol use disorder 2.
- Trial name
- NCT03823599
- Testing
- Mobile chat-based instant messages, Alcohol brief intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alcohol Misuse, Homeless
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Approximately 1 out of every 3 adults experiencing homelessness has a current alcohol use disorder (AUD). Alcohol use plays a central role in increased morbidity and mortality in this population, with some studies suggesting it…
- Trial name
- SmartT_A (NCT06821295)
- Testing
- Smart-T Alcohol, Usual Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Alcohol Dependency
Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility
An alcohol Screening, Brief Intervention and Referral to Treatment (SBIRT) approach will be adapted for use in a large military hospital setting, and then pilot tested in a military emergency department (ED) to assess its…
- Trial name
- NCT02228967
- Testing
- SBIRT
- Where
- United States
- Volunteers
- 791 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Cirrhosis, Alcohol Abuse
Fecal Microbial Transplant for Alcohol Misuse in Cirrhosis
There is an epidemic of alcohol use disorder in the US. Alcoholism is an epidemic that spans all ages and socio-economic strata, which has a major impact on healthcare expenditure.
- Trial name
- NCT03416751
- Testing
- Fecal Microbial Transplant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Alcohol Use Disorder, Alcohol Misuse
Human Laboratory Study of Apremilast for Alcohol Use Disorder
Primary: The primary objective of this study is to compare the efficacy of two different maintenance doses of apremilast (tablets) in reducing alcohol craving among subjects with moderate to severe alcohol use disorder (AUD)…
- Trial name
- NCT07325266
- Testing
- Apremilast
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Heavy Episodic Drinking
Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults
Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences.
- Trial name
- NCT06976528
- Testing
- Alcohol administration
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- New York University
Alcohol Misuse
Internet-delivered Therapy for Alcohol Misuse: Factorial Trial of Assessment and Guidance
Internet-delivered cognitive behaviour therapy (ICBT) shows considerable promise as a convenient treatment for alcohol misuse. ICBT may differ in whether the user works alone (self-guided) or along with an individual who guides…
- Trial name
- NCT03984786
- Testing
- Assessment Interview, Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 312 people
- Sponsor
- University of Regina
Insomnia, Alcohol Use
Brief Interventions to Reduce Comorbid Alcohol and Cannabis Misuse and Sleep Impairment in Young Adults (Rest-Up RCT)
This study is designed to evaluate an integrated intervention to reduce alcohol and marijuana use and consequences and improve sleep among young adults with comorbid heavy episodic drinking, marijuana use, and sleep impairment.
- Conditions
- Insomnia, Alcohol Use, Marijuana Use
- Trial name
- NCT06736444
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS), Attention Control
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Washington
Binge Drinking, Alcohol Drinking in College
Balanced Lifestyle for Undergraduate Excellence - Mobile (Project BLUEM)
The purpose of this study is to evaluate a text-message delivered approach for improving college adjustment and experience and reducing risky alcohol use in young adult college students.
- Conditions
- Binge Drinking, Alcohol Drinking in College, Behavior, Drinking, Behavior and Behavior Mechanisms
- Trial name
- BLUEM (NCT04105725)
- Testing
- Brief Motivational Intervention+Substance-Free Activity Session, Alcohol + Nutrition Education Session
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Memphis
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Consumption
Texting to Reduce Alcohol Misuse Pilot Trial
The primary aims of this project are to determine the feasibility and acceptability of recruiting and retaining young adult binge drinkers online and using text messaging to provide weekly Goal Support (GS) or weekly GS +…
- Trial name
- TRAM (NCT05864235)
- Testing
- Control, Goal Support (GS), Coaching for Context-specific Peer Support (CCPS)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Alcohol Misuse
Alcohol Brief Intervention Integrated With Mobile Chat-based Support for Risky Drinkers in Emergency Departments
This study aims to assess the effectiveness of chat-based intervention on reducing risky alcohol consumption to inform clinical practice for providing ABI to risky drinkers attending AED in Hong Kong.
- Trial name
- NCT05018624
- Testing
- Alcohol brief intervention, 12-page health warning leaflet, Regular messages through Instant Messaging (IM)
- Where
- Hong Kong
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prescription Drug Abuse, Substance Abuse
A High School Program for Preventing Prescription Drug Misuse
This project will develop and evaluate a program to prevent prescription drug misuse in high school students
- Conditions
- Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
- Trial name
- NCT03219190
- Testing
- LST High School Hybrid
- Where
- United States
- Volunteers
- 1,804 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Substance Use Disorder (SUD), Opioid Use Disorder
Disease Intervention Specialist (DIS) for SUD
This prospective observational study evaluates three Disease Intervention Specialist service models designed to proactively identify and support adults at risk for substance use disorder.
- Conditions
- Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use
- Trial name
- DIS-SUD (NCT07875361)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Ohio State University
Alcohol Use Disorder, Supplementation
Administration of Fiber as a Dietary Supplement to Improve the Management of Alcohol Withdrawal
The goal of this clinical trial is to demonstrate that a fiber-enriched diet (with a high proportion of inulin and pectin) combined with standard care can reduce intestinal permeability in patients with alcohol use disorder (AUD)…
- Conditions
- Alcohol Use Disorder, Supplementation, Intestinal Permeability
- Trial name
- FIB-ALC (NCT07371286)
- Testing
- Administration of fibers as a dietary supplement
- Volunteers
- 138 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Drinking, HIV Viremia
Using Telehealth to Address Alcohol Misuse in HIV Care
This project will test the effects of a telehealth counseling program on reducing alcohol use and improving HIV viral control among people with HIV who drink heavily.
- Trial name
- ReACH3 (NCT04546971)
- Testing
- Brief Intervention, Telehealth Counseling, Text messaging
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use, Unspecified
Behavioral Economic Treatment to Enhance Rural (BETTER) Living
The purpose of this trial is to get feedback to help develop programs delivered by phone and text messages to improve wellness and health behaviors.
- Trial name
- NCT05235971
- Testing
- Episodic Future thinking, Volitional choice, Monitoring only
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan
Posttraumatic Stress Disorder, Alcohol Use Disorders
Brief Restructuring Intervention Following Trauma Exposure
The broad aim of this study is to develop and test a brief intervention that can be implemented in the immediate weeks following sexual assault to decrease likelihood of developing posttraumatic stress disorder (PTSD) or alcohol…
- Trial name
- BRITE (NCT02808468)
- Testing
- Brief Cognitive Therapy
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Washington
Military Transition, Community Reintegration
Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans
The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life.
- Conditions
- Military Transition, Community Reintegration, Mental Health, Suicidal Ideation
- Trial name
- NCT06778278
- Testing
- Transition Health and Resilience through Valued Experiences (THRiVE) Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI International