Clinical trials: Alcohol Consumption
Sex, Unprotected Sex
Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents
The objective of this research study is to evaluate a culturally tailored sexual and reproductive health intervention among American Indian (AI) youth.
- Conditions
- Sex, Unprotected Sex, Contraception, Alcohol Use
- Trial name
- TPP (NCT02904629)
- Testing
- Respecting the Circle of Life (RCL), Control Program
- Where
- United States
- Volunteers
- 1,072 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV/AIDS and Infections, Drug Abuse
A Community-University Approach to Preventing HIV
Examine the feasibility and acceptability of delivering the S4E intervention to 20 African-American youths between the ages 16-21 in Flint, Michigan.
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03938077
- Testing
- Storytelling 4 Empowerment
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Alcohol Use Disorder
A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients
The project objective is to rigorously evaluate the effectiveness of a peer recovery coaching intervention (called RC-Link) in patients hospitalized with medical complications from alcohol use on recovery outcomes guided by the…
- Trial name
- RC-Link (NCT06479681)
- Testing
- Peer recovery coaching (PRC), Brief Intervention (SBIRT)
- Where
- 2 sites in United States
- Volunteers
- 750 people
- Sponsor
- Clemson University
Binge Drinking, Alcohol Abuse
Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
This study will determine whether a cognitive behavioral intervention that demonstrates strong evidence in the U.S. of reducing alcohol use is effective when delivered by paraprofessionals in Kenya and compared against a usual…
- Conditions
- Binge Drinking, Alcohol Abuse, Alcohol Dependence, HIV Infections
- Trial name
- KHBS (NCT00792519)
- Testing
- HIV support group, CBT
- Where
- Kenya
- Volunteers
- 75 people
- Sponsor
- Brown University
Nicotine Dependence, Tobacco Use
Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers
The project is designed to examine the effectiveness of strategies to increase access to treatment for tobacco use and dependence among rural Veteran smokers.
- Trial name
- NCT01892813
- Testing
- Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg
Alcohol Use Disorder
The Effects of Sex Hormones and Alcohol on Sleep
Rates of heavy drinking and Alcohol Use Disorder (AUD) are increasing in women, but research on alcohol-related harms in women - including alcohol's impact on sleep - has been minimal.
- Trial name
- NCT06143059
- Testing
- Ethanol, Saline
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Alcohol Use
Project Guard: Reducing Alcohol Misuse/Abuse in the National Guard
The overall goal for the study is to test the efficacy of a smartphone app which includes an alcohol brief intervention (SP-BI) versus an Enhanced Usual Care (EUC) condition for National Guard members in the State of Ohio who…
- Trial name
- NCT02860442
- Testing
- Smartphone brief intervention (SP-BI), Enhanced Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- Keming Gao
Breast Cancer
Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women
Postmenopausal women, stratified by a peroxisome proliferator-activated receptor gamma-2 (PPARG) polymorphism, were given the following treatments in a random order with a 5w wash-out period: a 400mg ibuprofen tablet or a placebo…
- Trial name
- EPPNASE (NCT02463383)
- Testing
- Ibuprofen Tab 400 MG
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Professor Lars Ove Dragsted
Alcohol-Induced Disorders, Nervous System, Alcohol Dependence
Health Mobile Cognitive Stimulation in Alcohol Use Disorder
The consequences of alcohol dependence are severe and may range from physical diseases to neuropsychological deficits in several cognitive domains.
- Trial name
- NCT01942954
- Testing
- Mobile health cognitive stimulation
- Where
- Portugal
- Volunteers
- 54 people
- Sponsor
- Pedro Gamito
Alcohol Drinking, Alcohol Problem Drinking
Parent Feedback Intervention Targeting Student Transitions and Alcohol Related Trajectories (+) Efficacy Study
FITSTART (Feedback Intervention Targeting Student Transitions and Risk Trajectories) is a parent-based social norms intervention that has been shown to reduce risky drinking in incoming first year students.This program uses…
- Conditions
- Alcohol Drinking, Alcohol Problem Drinking, Parenting
- Trial name
- FITSTART+ (NCT04549454)
- Testing
- FITSTART+ PBI, General Parenting Advice
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Alcohol Drinking
Imaging Glutamate Release From Alcohol
The goal of this research project is to determine the sensitivity of PET radioligands specific for targets in the glutamate system to an alcohol challenge.
- Trial name
- NCT04159688
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol; Use, Problem, Marijuana Usage
Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users
This is a pilot study of the feasibility, acceptability, and effectiveness of a brief, one-session intervention for a diverse sample of 44 young adults who report alcohol binge drinking or marijuana use in the past month.
- Trial name
- NCT03801096
- Testing
- Narrative Based Therapuetic Assessment (NbTa), Health Education Control Condition (HE)
- Volunteers
- 44 people
- Sponsor
- University of Houston
Hepatitis B Virus, HIV
Antiretroviral Treatment Outcomes in HIV-HBV Co-infected Patients in Southern Africa
This is a prospective HIV cohort that aims to establish causes of liver disease among HIV-infected individuals in Zambia, including viral hepatitis and alcohol.
- Conditions
- Hepatitis B Virus, HIV, Antiretroviral Therapy, Africa
- Trial name
- NCT02060162
- Testing
- Standard of care
- Where
- Zambia
- Volunteers
- 897 people
- Sponsor
- University of Alabama at Birmingham
Liver Diseases, Alcoholic, Alcoholism
Integrated Stepped Care for Unhealthy Alcohol Use in HIV
The study is a series of 3 linked randomized clinical trials of 6 month duration, with a total of 12 month follow-up, to evaluate the effect of Integrated Stepped Care on drinking outcomes and HIV biologic markers (including VACS…
- Conditions
- Liver Diseases, Alcoholic, Alcoholism, HIV, Hepatitis C
- Trial name
- NCT01410123
- Testing
- Integrated Stepped Care (ISC), Treatment as Usual
- Where
- 5 sites in United States
- Volunteers
- 319 people
- Sponsor
- Yale University
Alcohol Metabolism Modifier Adverse Reaction, Bariatric Surgery Candidate
Alcohol Metabolism After Sleeve Gastrectomy
This prospective study aimed to determine the alcohol intake symptoms and alcohol metabolism before and 12 months after sleeve gastrectomy (SG) by evaluating blood alcohol content (BAC) and urinary alcohol metabolite levels…
- Trial name
- NCT04079023
- Testing
- Sleeve Gastrectomy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Neuropathic Pain, Anxiety Disorder/Anxiety State
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological…
- Conditions
- Neuropathic Pain, Anxiety Disorder/Anxiety State, Pain, Chronic, Alcohol Use Disorder
- Trial name
- DIP-CAOS (NCT05505188)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Alcohol Use Disorder
Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders
Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment for reducing alcohol use
- Trial name
- NCT02742246
- Testing
- Individual clinician-provided CBT, CBT4CBT
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Yale University
Cannabis Use Disorder
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use.
- Trial name
- NCT06446479
- Testing
- Dronabinol Pill
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Drinking
Social Effects of Alcohol
In this study the investigator will assess the effect of a moderate dose of alcohol on emotional responses and feelings of connection during a dyadic semi-structured social interaction
- Trial name
- SEA (NCT05826951)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol Use Disorder, Alcohol Craving
Eye Movements Desensitization and Reprocessing Intervention in Preventing Craving in Alcohol Use Disorder
This study is conducted to examine the effect of a psychotherapy model that is expected to affect alcohol cravings in adults aged 18-65 years who are being treated for alcohol use disorder at a clinic.
- Trial name
- NCT05606900
- Testing
- addiction-focused eye movements desensitization and reprocessing (AF-EMDR)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University