Clinical trials: Alcohol Consumption
Alcohol Use Disorder
Diclofenac as a KMO Inhibitor
This mechanistic, proof of concept laboratory study will test the pharmacological properties of diclofenac in individuals with AUD.
- Trial name
- DKMOI (NCT06029296)
- Testing
- Diclofenac
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Maryland, Baltimore
Alcohol Consumption, Alcohol Use Disorder
Effectiveness of an Intervention in Patients With Excessive Alcohol Consumption
Main objective: to verify the effectiveness of a brief intervention, based on the motivational interview (MI), in patients with excessive alcohol consumption assisted in Primary Care (PC).
- Trial name
- ALCO-AP20 (NCT04811729)
- Testing
- Motivational interview, Medical advice
- Where
- Spain
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Alcohol Use, Unspecified
Risk Factors for Stress-induced Alcohol Misuse: Genetic Predictors and Mediation by Personality Type
To examine whether variation in 'risk-taking' personality and linked genetic variants predicts susceptibility to, and resilience against, stress-induced alcohol misuse.
- Trial name
- RISK (NCT04533802)
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Alcohol Use Disorder (AUD), Alcoholism
Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer
Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans.
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders, Smoking, Tobacco
- Trial name
- ReCoDe (NCT05992272)
- Testing
- fMRI imaging (BOLD), sMRI (structure), Trier Social Stress Test
- Where
- 2 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Common Mental Disorders, Alcohol Use Disorder
Mental Health and Well-being of People Who Seek Help From Their Member of Parliament
This is an observational study to assess the prevalence of common mental disorders and alcohol use disorders in a population of individuals seeking help from their Member of Parliament (MP) in the UK.
- Trial name
- NCT04203966
- Testing
- 12-item General Health Questionnaire (GHQ-12), WHO AUDIT (World Health Organization- Alcohol Use Disorders Inventory Tool)
- Where
- United Kingdom
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Drinking, Violence
SafERteens M-Coach
This study will use a SMART (Sequential, Multiple Assignment Randomized Trial) design to optimize adaptive interventions (AIs) for adolescents reporting alcohol misuse and violent behaviors.
- Trial name
- NCT03344666
- Testing
- Step 1 Treatment BI+HC, Step 1 Treatment BI+TM, Step 2 Treatment Responders
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Unhealthy Alcohol Use, Alcohol Use Disorder
Relational Agent for Alcohol Screening and Treatment
This project will involve the development and initial evaluation of a promising computer-based intervention to improve the primary care management of risky alcohol use among Veterans.
- Conditions
- Unhealthy Alcohol Use, Alcohol Use Disorder, Alcohol Disorders
- Trial name
- RAAST (NCT02030288)
- Testing
- Relational Agent Intervention
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Housing Problems, Drug Use
ED-Home Pilot Study
This is a single-arm pilot study to test the feasibility of homelessness prevention and substance use interventions to be delivered to at-risk patients in the Bellevue Hospital emergency department (ED).
- Conditions
- Housing Problems, Drug Use, Alcohol; Use, Problem
- Trial name
- NCT03864341
- Testing
- Referral to homelessness prevention services, Substance use services, Follow-up
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Alcohol Drinking, Alcohol Abuse
A Gamified, Social Media Inspired Personalized Normative Feedback Alcohol Intervention for Sexual Minority Women
Sexual minority women in the United States are more likely to drink alcohol, engage in heavy drinking, and experience alcohol-related problems than are heterosexual women.
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol; Harmful Use
- Trial name
- NCT03884478
- Testing
- Personalized Normative Feedback
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Alcohol Abuse, Alcohol Drinking
TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda
The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
- Trial name
- TREAT C-AUD (NCT04743024)
- Where
- Uganda
- Volunteers
- 7,188 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Alcohol Abuse, Drug Abuse
Personality-targeted Interventions for Adolescent Alcohol Misuse
Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press).
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Preventure (NCT00344474)
- Testing
- PRE-Venture: Personality Risk Education
- Where
- United Kingdom
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Use Disorder
Alcohol Use Disorder and Cannabidiol
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use…
- Trial name
- NCT05613608
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Colorado, Denver
Alcohol Consumption
Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Background: People who binge drink are more likely to have risky sexual encounters, and alcohol changes brain activity associated with reward decisions related to those behaviors.
- Trial name
- NCT04360018
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Problematic Alcohol Use
E-alcohol Therapy - an Evaluation of Alcohol Therapy Delivered Via Video Conference
The study evaluates whether the introduction of e-alcohol therapy (alcohol therapy delivered via video conference) can break with some of the barriers related to alcohol treatment and thereby appeal to people with a problematic…
- Trial name
- NCT03116282
- Testing
- E-alcohol therapy
- Where
- Denmark
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Addiction, Addiction Disorders
Can Selfcompassion Training Reduce Alcohol Consumption in Patients With Alcohol Use Disosrder ?
The objective of this interventional study is to evaluate the effectiveness of the Mindful Self-Compassion (MSC) program in reducing alcohol consumption in a population of individuals with Alcohol Use Disorder (AUD), six months…
- Conditions
- Addiction, Addiction Disorders, Alcohol Use Disorders, Alcohol Dependence
- Trial name
- COMPAL (NCT07131124)
- Testing
- Mindful Self-Compassion program, Treatment As Usual (TAU) program
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Alcohol Consumption, Drug Abuse
Self-Selected Brief Alcohol Intervention for Adolescents
Alcohol use among youth continues to be a major concern for this nation, with a large proportion of adolescents increasing their alcohol consumption as they transition from the 6th to the 8th grade.
- Trial name
- NCT00383838
- Testing
- brief, voluntary substance use intervention
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RAND
HIV Infections, HIV/AIDS
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
The purpose of this early Phase 2 comparison trial is to evaluate the impact of community health worker (CHW) home visitors on pregnant women and their children in a rural setting in the rural Eastern Cape of South Africa.
- Conditions
- HIV Infections, HIV/AIDS, Depression, Depressive Symptoms
- Trial name
- NCT03517878
- Testing
- Comprehensive CHW Program
- Where
- 2 sites in South Africa
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Substance Use Disorders, Opioid Use Disorder
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD)…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder
- Trial name
- EDITOR (NCT06434818)
- Testing
- EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Evon Medics LLC
Binge Drinking, Alcohol Drinking in College
Balanced Lifestyle for Undergraduate Excellence - Mobile (Project BLUEM)
The purpose of this study is to evaluate a text-message delivered approach for improving college adjustment and experience and reducing risky alcohol use in young adult college students.
- Conditions
- Binge Drinking, Alcohol Drinking in College, Behavior, Drinking, Behavior and Behavior Mechanisms
- Trial name
- BLUEM (NCT04105725)
- Testing
- Brief Motivational Intervention+Substance-Free Activity Session, Alcohol + Nutrition Education Session
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Memphis