Clinical trials: Alcohol Addiction
Alcohol Use Disorder (AUD)
Records for Alcohol Care Enhancement
Unhealthy alcohol use (the spectrum from risky consumption through alcohol use disorder, AUD) is a leading cause of preventable death in the US (88,424 deaths annually costing $249 billion a year), and alcohol-related health…
- Trial name
- RACE (NCT05492942)
- Testing
- Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Alcohol Use Disorder (AUD), PTSD
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
This is a two-part study to develop and test a brief, virtual therapy program for lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people who have experienced trauma and use alcohol.
- Trial name
- RISE (NCT07217795)
- Testing
- CBT + expressive writing, Wait-List Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Rhode Island
Alcohol Dependence
The Approach and Avoidance Task (AAT) in Alcoholic Inpatients
The approach and avoidance task (AAT) has evolved as a promising treatment add-on in the realm of psychology. Certain psychiatric diseases, such as behavioural addictions, social anxiety disorder, and arachnophobia, are…
- Trial name
- NCT04054336
- Testing
- Inhibit AAT, classical AAT, Control Group
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Primary Alcohol Use Disorder
Ketamine for Reduction of Alcoholic Relapse
96 recently detoxified alcoholics will be randomized to receive either 3 sessions ketamine (0.8 mg/kg IV over 45 minutes) or placebo plus manualised psychological therapy, or 3 sessions of ketamine or placebo plus simple…
- Trial name
- KARE (NCT02649231)
- Testing
- Ketamine, Psychological Therapy, Alcohol Education
- Where
- 2 sites in United Kingdom
- Volunteers
- 96 people
- Sponsor
- University College, London
Ptsd, Alcohol Use Disorder
Early Intervention Following Sexual Assault
This study is for women who have experienced a sexual assault in the past six weeks and use alcohol. The research involves completing a five week behavioral treatment for stress and alcohol use.
- Conditions
- Ptsd, Alcohol Use Disorder, Sexual Assault and Rape
- Trial name
- NCT04582695
- Testing
- Written Exposure Therapy Integrated with Cognitive Behavioral Therapy for Alcohol Use Disorder, Written Exposure Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Alcoholism
Use of Naltrexone in a Clinical Setting
This 12-week trial will compare individuals receiving naltrexone or placebo plus substance abuse counseling therapy versus those receiving only substance abuse counseling therapy in a rural, nonacademic setting.
- Trial name
- NCT00000445
- Testing
- naltrexone (Revia)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Bipolar Disorders
Bipolar Disorder With Alcoholism in Han Chinese
The aim of this study is to explore relation between the comorbidity of different bipolar disorders with alcoholism and neuropsychiatric function and candidate genes.
- Trial name
- NCT01188395
- Where
- Taiwan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Alcohol Dependence
Advanced Nurses vs. General Practitioners for the Management of Outpatient Alcohol Detox: a Safety and Cost Comparison
The SAMBA study aims to assess the safety and cost comparison of the management of outpatient alcohol detoxification, between an advanced nurse protocol on the one hand (experimental group), and a GP-based treatment on the other…
- Trial name
- SAMBA (NCT03056365)
- Testing
- Advanced Nurse (AN), General Practitioner (GP)
- Where
- 26 sites in France
- Volunteers
- 73 people
- Sponsor
- University Hospital, Lille
Alcohol Abuse
Brief Intervention for Heavy Drinkers
The purpose of the study is to determine whether a brief intervention (a short conversation build on the principles of motivational interviewing) is effective in lowering self reported alcohol use in heavy drinkers.
- Trial name
- NCT00728767
- Testing
- Brief intervention, Control group
- Where
- 9 sites in Denmark
- Volunteers
- 772 people
- Sponsor
- University of Southern Denmark
Addiction, Substance, COVID-19
Evolution of Psychoactive Substances Consumption in Connection With COVID-19 Containment
The current containment linked to COVID-19 will have consequences for people suffering from addiction and there is a risk of overdoses when the containment ends.
- Trial name
- EPILOGUE (NCT04343339)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Depressive Disorder, Major, Alcoholism
Vortioxetine for Treatment of Depressive Mood and Alcohol Use
This is a randomized, double-blinded, placebo-controlled, multicenter study. A total of 128 subjects will be randomly assigned to a test group or placebo group in a 1:1 ratio.
- Trial name
- NCT04498897
- Testing
- Vortioxetine, Acamprosate
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Hanyang University Seoul Hospital
Alcoholism
ALK21-006: Long-Term Study of Medisorb® Naltrexone (VIVITROL®)
This was a Phase 3 multicenter randomized, open-label, safety study assessing the safety of repeat doses of Medisorb® naltrexone 380 mg (VIVITROL®) administered for up to 1 year to adults with alcohol and/or opioid dependence as…
- Trial name
- NCT01218997
- Testing
- Medisorb naltrexone 380 mg, Oral naltrexone 50 mg
- Volunteers
- 436 people
- Sponsor
- Alkermes, Inc.
Alcohol Use Disorder, Post Traumatic Stress Disorder
Stress, Emotion Regulation, and Alcohol in Women Veterans
The purpose of the study "Stress, Emotion Regulation, and Alcohol in Women Veterans" is to learn about the effects of negative emotion and stress on behavior (including alcohol use) among women Veterans, including women with and…
- Trial name
- SERA (NCT04393623)
- Testing
- Cognitive Reappraisal, Psychoeducation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Alcohol Abuse, Criminal Behavior
Mindfulness for Alcohol Abusing Offenders
Over half of state and federal prisoners meet clinical criteria for alcohol abuse or dependence, and after release from prison, over three-quarters of offenders are re-arrested within five years.
- Trial name
- MIT (NCT03883646)
- Testing
- Mindfulness, Relapse Prevention
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- The Mind Research Network
Alcohol Dependence
Network Support for Treatment of Alcohol Dependence
Relapse is the most serious problem in alcoholism treatment. The overall aim of the present study was to determine if a treatment directed at changing the patient's social network, from one that reinforces drinking behavior to…
- Trial name
- NCT00845208
- Testing
- Network Support
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- UConn Health
Alcohol Use Disorder, Contingency Management
Dual Reinforcement Contingency Management for Alcohol Use Disorders
Phosphatidylethanol (PEth) is a direct biomarker of alcohol that can detect moderate to heavy drinking with high sensitivity and specificity over 3-week periods.
- Trial name
- Peth (NCT04064463)
- Testing
- Standard care, Contingency management
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- UConn Health
Bipolar Disorders, Schizophrenia
Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI)
The primary aim of this study is to determine the feasibility of long-acting injectable naltrexone administration in a clinical trial in patients with SMI who also have a diagnosis of alcohol dependence.
- Conditions
- Bipolar Disorders, Schizophrenia, Schizoaffective Disorders, Alcohol Dependence
- Trial name
- vivitrol (NCT00453804)
- Testing
- injectable naltrexone, oral naltrexone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- State University of New York - Upstate Medical University
Alcohol Use Disorder
Methylphenidate and Response to Alcohol Cues
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues.
- Trial name
- NCT07306078
- Testing
- Methylphenidate Pill
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida