Clinical trials: Alcohol; Use, Problem
Alcohol Dependence, Alcohol Abuse
A Smartphone Based Intervention for the Prevention of Relapse in Alcohol Dependence
The rate of relapse following an inpatient alcohol rehabilitation program has been around 50% for a number of years. Offered treatments mainly focus on conscious and controllable aspects of behaviour, but research has found that…
- Conditions
- Alcohol Dependence, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- SPIRA (NCT03952429)
- Testing
- Anti Alcohol App with Active Cognitive Bias, Inactive Cognitive Bias Modification
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Salus Klinik Lindow
Alcohol Use Disorder
Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers
This study will examine the neural mechanisms underlying both spontaneous behavior change and behavior change in response to a brief intervention among problem drinkers.
- Trial name
- NCT03457077
- Testing
- Brief intervention
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Depression, Alcoholism
Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism
We will study patients with a current major depressive episode, comorbid alcoholism and a history of a past suicide attempt. All subjects with alcohol dependence will be evaluated for risk of alcohol withdrawal prior to…
- Conditions
- Depression, Alcoholism, Suicidal Behavior
- Trial name
- NCT00449007
- Testing
- fluoxetine, bupropion
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Alcohol Dependence
Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence
The purpose of this study was to assess efficacy and safety of the study drug Odelepran, 125 mg as compared to placebo in the treatment of alcohol dependence in adult outpatients.
- Trial name
- NCT03663374
- Testing
- Odelepan
- Where
- 22 sites in Kazakhstan, Russia
- Volunteers
- 644 people
- Sponsor
- R-Pharm
Alcohol Problem
Game-Based Intervention to Reduce Alcohol Use Among Youth
This is a randomized controlled trial to learn if the Singularities, a game-based intervention, works to reduce alcohol-related harms among youth.
- Trial name
- NCT07463118
- Testing
- Food4Thought, Singularities
- Where
- United States
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Consumption, Alcohol Abuse/Dependence
Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults.
- Trial name
- PALS (NCT06627803)
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Drug Overdose, Substance Abuse
EEG Monitoring in the Emergency Department
This study seeks to investigate whether drug effects in suspected overdose patients could be identified using the electroencephalogram (EEG).
- Conditions
- Drug Overdose, Substance Abuse, Alcohol Abuse
- Trial name
- NCT04070521
- Testing
- Observational EEG Monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
Research of Prevention and Intervention of Mental Health Problems
The purpose of this research is to establish a suitable community-based model for Chinese culture,to improve the community recognition of common mental disorders,as well as its treatment and control.
- Conditions
- Anxiety, Depression, Alcohol-abuse
- Trial name
- RPIMHP (NCT01422447)
- Testing
- regular intervention, community intervention
- Where
- 7 sites in China
- Volunteers
- 42,016 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Abuse
Human Alcohol Seeking Despite Aversion
Prolonged alcohol use results in drinking despite resultant problems and adverse consequences. The investigators propose to test a laboratory model of human seeking despite aversion to use as an early marker of disease onset, and…
- Trial name
- NCT03648840
- Testing
- Aversive Cue, Neutral Cue
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Indiana University
PTSD, Alcohol Abuse
Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT
This project begins to evaluate the effectiveness of a web-based family outreach tool that is designed to promote treatment engagement among Veterans with posttraumatic stress disorder (PTSD) or alcohol use disorders (AUDs) but…
- Trial name
- NCT01678196
- Testing
- VA-CRAFT, Control
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Alcohol Abuse, Nervous System
A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment
The study primary end point is the decrease in the number of monthly heavy drinking days (HDD) (≥ 60 g/day in men and ≥ 40 g/d in women) from baseline to the end of the double blind Randomized Treatment (RT).
- Trial name
- PoC Alcohol (NCT02800083)
- Testing
- Pitolisant (BF2.649)
- Sponsor
- Bioprojet
Alcohol Abuse in Pregnancy
Effectiveness of Repeated MOTivational InterVention to Reduce Ethanol Intake During prEgnancy
Ethanol exposure during pregnancy is associated with adverse perinatal outcomes resulting in high healthcare costs. Primary care centers whose attends low risk women will be randomized to apply a motivational intervention program…
- Trial name
- EMOTIVE (NCT04275570)
- Testing
- Motivational interview
- Where
- 2 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Alcohol Abuse, Anxiety
A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking
The purpose of this study is to develop and examine a culturally adapted, mobile health application for the Android and iOS platform.
- Trial name
- NCT06416059
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Houston
Alcohol Abuse
Emotion Regulation Interventions for Preventing Collegiate Escalations in Drinking
In the most recent National Survey on Drug Use and Health (NSDUH), college aged respondents between 18 and 25 years old reported the highest alcohol use rates (over 58%) as well as the highest rates of binge drinking of any age…
- Trial name
- PACER (NCT04492982)
- Testing
- Yoga, Distress Tolerance
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of Connecticut
Bipolar Disorder, Alcoholism
Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
The investigators will conduct a 12-week, randomized, double-blind, parallel-group, placebo-controlled study of aripiprazole in 132 persons with Alcohol Use Disorder (AUD) and bipolar I or II disorder, currently depressed or…
- Conditions
- Bipolar Disorder, Alcoholism, Alcohol Abuse
- Trial name
- NCT02918370
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Texas Southwestern Medical Center
Alcohol Abuse, Alcohol Dependence
Efficacy Trial of Warrior Check-Up
This study will develop and test a brief telephone-delivered motivational enhancement intervention for substance abusing military personnel who are not currently in treatment.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Substance Abuse, Substance Dependence
- Trial name
- NCT01128140
- Testing
- Motivational Enhancement Therapy, Education
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- University of Washington
Smoking
Combined Treatment for Tobacco and Alcohol Use in Puerto Rico
Objectives: 1. Assess MAPS and MAPS+ effects on alcohol at-risk behaviors and smoking cessation. 2. Assess MAPS and MAPS+ effects on treatment mechanisms (increased self-efficacy, decreased temptations/craving, decreased stress…
- Trial name
- NCT00570804
- Testing
- Telephone Counseling, Telephone Assessments
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Alcohol-Related Disorders, Alcohol Use Disorders
Component Analysis for Motivational Interviewing
The purpose of this study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01642381
- Testing
- Full Motivational Interviewing ("FMI"), Spirit Only Motivational Interviewing ("SOMI")
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Northwell Health
Alcohol Use Disorder
Pilot Trial to Evaluate PROblem Solving Therapy and APPLE Watch for College Students
The goals of this Pilot Trial are to test the preliminary efficacy of Problom-Solving Therapy (PST)-APPLE Watch in a 2-arm pilot Randomized Control Trial (RCT), vs education only-control to reduce alcohol use disorder symptoms…
- Trial name
- NCT06333288
- Testing
- PST-APPLE Watch group, Education-only control group
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago