Clinical trials: Airway Disease
Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD)
Immune Status and Disease Control of Inflammatory Airway Diseases
The goal of this study is to learn how the body's immune system affects disease control in people with different airway inflammatory diseases.We want to understand: 1.Whether specific immune cell patterns in the blood are linked…
- Conditions
- Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Bronchiectasis
- Trial name
- ISDC-IAD (NCT07493629)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Obstructive Sleep Apnea
Effects of PAP Treatment of OSA in Patients With Heart Failure
The purpose of this study is to see if treatment of OSA with the CPAP device makes a difference to insulin resistance and heart disease.
- Trial name
- OSA-MRI (NCT01136122)
- Testing
- CPAP Treatment
- Where
- United States
- Sponsor
- Ulysses Magalang MD
Pulmonary Disease, Chronic Obstructive, Emphysema
Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant
The goal of the small feasibility trial is to establish a method, material, and patient-specific design that is superior to what is in use today.
- Trial name
- NCT03111888
- Testing
- Silicone Stent Airway Implant
- Where
- United States
- Sponsor
- The Cleveland Clinic
COPD (Chronic Obstructive Pulmonary Disease)
A Clinical Study of REGEND001 for the Treatment of Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a common, progressive, and heterogeneous respiratory disorder. It is associated with substantial morbidity and mortality worldwide, leading to progressive decline in lung function…
- Trial name
- NCT07828353
- Testing
- REGEND001
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Regend Therapeutics
Cystic Fibrosis, Airway Clearance Impairment
IPV vs CPT for Airway Clearance During CF Exacerbation
Intrapulmonary Percussive Ventilation (IPV) will show greater improvements in Forced Expiatory Volume in 1 second (FEV1) shorter duration of stay, and greater time to next pulmonary exacerbation in pediatric Cystic Fibrosis…
- Trial name
- NCT03261219
- Testing
- Intrapulmonary Percussive ventilation, Chest Physiotherapy Vest (Incourage)
- Sponsor
- University of Florida
Seasonal Allergic Rhinitis
POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)
Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
- Trial name
- NCT00160537
- Testing
- Levocetirizine
- Volunteers
- 200 people
- Sponsor
- UCB Pharma
Allergic Rhinitis, Allergic Conjunctivitis
Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray
Intranasal corticosteroids are accepted as safe and effective first-line therapy for allergic rhinitis, especially in treatment of persistent symptoms.
- Conditions
- Allergic Rhinitis, Allergic Conjunctivitis, Hayfever
- Trial name
- NCT03755557
- Testing
- Rhinocort, Budesolv
- Where
- Austria
- Volunteers
- 82 people
- Sponsor
- Marinomed Biotech AG
Anesthesia, Intravenous, Spontaneous Breathing
Respiratory Monitoring in Supraglottic Airway Anesthesia
This prospective observational study evaluates the feasibility and clinical utility of AI-enhanced continuous respiratory sound monitoring during intravenous anesthesia with supraglottic airway placement.
- Trial name
- NCT07275801
- Testing
- Standard Airmod Respiratory Monitoring
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea
Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial
The goal of this clinical trial in adults with obstructive sleep apnea prescribed positive airway pressure therapy is to test the effects of a new patient-facing consumer wearable-based program (that involves provision of a…
- Trial name
- mPAP (NCT06039865)
- Testing
- Immediate Intervention, Waitlist control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Rheumatoid Arthritis, Interstitial Lung Disease
Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease
The overall goal of this study is to define the phenotype of Interstitial Lung Disease (ILD), and identify factors that predict radiologic progression in those with subclinical RA-ILD, in patients with rheumatoid arthritis (RA).
- Trial name
- RAPID (NCT03297775)
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- University of Colorado, Denver
Asthma
Efficacy of Ciclesonide on Small Airways in Patients With Stable Asthma (18 to 60 y) (BY9010/M1-131)
The aim of this study is to evaluate the involvement of small airways in asthma, as determined by bronchial challenges, CT-scanning, and cellular markers of inflammation. Ciclesonide will be inhaled at one dose level once daily.
- Trial name
- NCT00163345
- Testing
- Ciclesonide
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Right Heart Failure, Mechanical Ventilation
Effect of APRV vs. LTV on Right Heart Function in ARDS Patients: a Single-center Randomized Controlled Study
Acute Respiratory Distress Syndrome (ARDS) is often complicated by Right Ventricular Dysfunction (RVD), and the incidence can be as high as 64%.
- Conditions
- Right Heart Failure, Mechanical Ventilation, Acute Respiratory Distress Syndrome
- Trial name
- NCT05922631
- Testing
- Airway pressure release ventilation, low tidal volume
- Where
- China
- Volunteers
- 60 people
- Sponsor
- XiaoJing Zou,MD
Airway Response, Lung Transplant Recipients
Bronchial Response to Exercise After Double Lung Transplantation
This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.
- Conditions
- Airway Response, Lung Transplant Recipients, Lung Transplant, Challenge Test
- Trial name
- NCT07035743
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Copd
Early Rehabilitation Program In Critically Ill Chronic Obstructed Airway Disease Patients
this study aim to compare the effect of early rehabilitation program on mechanical ventilated COPD patient in Respiratory ICU to those using current standard care as regarding : morbidity and thirty day mortality diaphragm…
- Trial name
- NCT03253380
- Testing
- Early Rehabilitation Program In Critically Ill Chronic Obstructed Airway Disease patients
- Volunteers
- 60 people
- Sponsor
- Hend mohammed sayed mohammed
Anesthesia Intubation Complication
Muscle Relaxants on Efficacy of LMA Insertion
The use of laryngeal mask airway (LMA) is increasing in pediatric anesthesia because it provides lesser direct mechanical stimulation of the airway due to being placed above the larynx.
- Trial name
- LMA_MR (NCT03487003)
- Testing
- rocuronium, saline
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Daegu Catholic University Medical Center
Asthma
Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study)
This will be a single site, mechanistic study of asthmatic subjects and healthy, non-asthmatic controls involving a baseline characterization visit and a research bronchoscopy visit.
- Trial name
- SEARCH (NCT02791542)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Lung Disease,Obstructive
Airway Responsiveness in Patients With AECOPD Mechanical Ventilation by Inspiratory and Bronchial Dilation Testchronic Obstructive Pulmonary Disease
In the patients with COPD mechanical ventilation, the bronchial dilatation is very common. However, the evaluation of the efficacy of the medical examination and other subjective indicators, such as doctors, depends on the…
- Trial name
- NCT02592122
- Testing
- Salbutamol Aerosol, No drugs
- Where
- China
- Volunteers
- 120 people
- Sponsor
- snow
Sleep Apnea Syndromes
Detection of Airway Obstruction by Manometry in Different Sleep Stages and Comparing it to DISE
Patients with OSA receive manometry measurements with Apneagraph (AG) during one night of sleep. All patients are simultaneously evaluated with polysomnography.
- Trial name
- NCT02969551
- Testing
- Manometry and possibly DISE
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Sleep Apnea, Obstructive
Adherence to Continuous Positive Airway Pressure Among Obstructive Sleep Apnoea Patients.
Prospective study designed to identify factors that would predict patient adherence to CPAP (Continuous Positive Airway Pressure) therapy.
- Trial name
- NCT02055027
- Testing
- Comparison between groups
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Astes
Respiratory Distress Syndrome (RDS), Neonatal Diseases and Abnormalities
Nasal High Frequency in Preterm Neonates
One of the most commonly used non-invasive methods is nasal continuous positive airway pressure (nCPAP). Although high frequency ventilation (HFV) has been applied in many neonatal intensive care units, nasal high frequency…
- Trial name
- NCT06687083
- Testing
- nasal high frequency oscillatory ventilation mode, nasal continuous positive pressure ventilation mode
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
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