Clinical trials: Airway Complications
Complication
Is Positive Pressure Extubation a Safe Procedure?
Laboratory studies suggest extubation with positive pressure because it reduces the volume of secretions filtered into the distal airway.
- Trial name
- NCT03174509
- Testing
- Positive pressure extubation, Traditional during extubation
- Where
- Argentina
- Volunteers
- 198 people
- Sponsor
- Hospital Donación Francisco Santojanni
Airway Complication of Anesthesia
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
The main objective of this study was to investigate whether propofol assisted extubation could reduce the incidence of respiratory adverse events in children with tonsil adenoidectomy.
- Trial name
- NCT05769842
- Testing
- propofol, normal saline
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Children's Hospital of Fudan University
Postoperative Complications, Intubation; Difficult or Failed
Discomfort in Upper Airways Due to intubation-a Randomized Controlled Trial
Few studies have compared different methods for optimalizing intubation conditions in general anesthesia. This randomized controlled trial will compare two different methods for intubation in general anesthesia in gastro- or…
- Conditions
- Postoperative Complications, Intubation; Difficult or Failed, Intubation Complication
- Trial name
- NCT05614609
- Testing
- Lidocaine topical
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Ostfold University College
Pulmonary Complication
Supraglottic Airway vs Tracheal Intubation on PPCs Among High-risk Geriatric Patients
Postoperative pulmonary complications are serious threat to surgical patients, especially to high-risk geriatric patients. There is evidence that laryngeal mask airway is associated with postoperative pulmonary complications in…
- Trial name
- NCT06391333
- Testing
- laryngeal mask airway and endotracheal tube
- Volunteers
- 2,210 people
- Sponsor
- RenJi Hospital
Intubation Complication, Intubation;Difficult
McGRATH vs Macintosh Laryngoscopy Comparison in LMA Insertion
Various techniques have been developed to get a good LMA position, one of them is using a laryngoscope. The most popular laryngoscope used for LMA installation is the Macintosh type.
- Conditions
- Intubation Complication, Intubation;Difficult, Anesthesia
- Trial name
- GRAN-PALM (NCT04509453)
- Testing
- McGRATH laryngoscopy, Macintosh laryngoscopy
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- Udayana University
Airway Complication of Anesthesia
Impact of Change of Head and Neck Position on Cricothyroid Membrane Localization and Membrane Height in Parturient Patients
The cricothyroid membrane acts a route through which the upper airway can be accessed in order to provide oxygen and ventilation to patients.
- Trial name
- NCT04138121
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Airway Complication of Anesthesia
A Study Comparing the Laryngeal Mask Airway Supreme With the Laryngeal Mask Airway Protector In the Ambulatory Surgery Unit
The Laryngeal Mask Airway is a supraglottic airway device that has been used in anesthesia for decades. Now the third generation (LMA Supreme) is commonly used. Recently the LMA Protector is manufactured.
- Trial name
- NCT03462550
- Testing
- Laryngeal mask
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal)
Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study
The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS).
- Conditions
- Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Respiratory Distress Syndrome of Newborn
- Trial name
- NCT07550218
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Continuous Positive Airway Pressure, Apnea of Prematurity
Randomized Trial Investigating Four Nasal CPAP Systems in the Management of Apnea of Prematurity
The purpose of this study is to evaluate four different nasal continuous pressure systems, which are usually applied on our neonatal intensive care unit, with regard of their effect on bradycardia and desaturations in preterm…
- Conditions
- Continuous Positive Airway Pressure, Apnea of Prematurity, CPAP
- Trial name
- NCT00482040
- Testing
- Stephanie (TM), Infant Flow (TM), Infant Flow advance (TM), Bubble CPAP
- Volunteers
- 16 people
- Sponsor
- University Hospital Tuebingen
Airway Management, Intubation; Difficult or Failed
Data-driven Development of a Core Dataset for Difficult Airway Alerts
Previous difficult airway management is the most accurate predictor of future difficulty. Consistent documentation is paramount for future airway planning, but requires reliable, reproducible and easily accessible information.
- Conditions
- Airway Management, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- FingAIRprint (NCT07275567)
- Where
- Germany
- Volunteers
- 1,785 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Fixation Device; Complications
LMA Fixation Method
Proseal laryngeal mask airway (LMA) is frequently used for safe airway management in modern anesthesia. Improper fixation of the LMA may result in subsequent displacement despite initial correct placement.
- Trial name
- NCT05433740
- Testing
- Proseal Laryngeal mask fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Supraglottic Airway Obstruction, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
Sedoanalgesia is applied to patients during gastrointestinal endoscopy. Sedoanalgesia may cause respiratory depression and hypoxia in patients.
- Conditions
- Supraglottic Airway Obstruction, Airway Complication of Anesthesia, Airway Obstruction, Anesthesia Complication
- Trial name
- NCT05783050
- Testing
- Wei Nasal Jet Tube, Nasal Cannula Oxygen Support
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Asthma, Vitamin D Resistant Rickets
Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent Patients
Research Title: Evaluation of airway reactivity, allergy and inflammatory mediators in exhaled breath condensate in vitamin D resistant rickets.
- Trial name
- NCT01578824
- Testing
- Methacholine Challenge Test
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Supraglottic Airway Efficiency, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
The most common adverse event in endoscopic procedures is hypoxia. Different airway devices have been investigated in the literature to prevent hypoxia.
- Conditions
- Supraglottic Airway Efficiency, Airway Complication of Anesthesia, Airway Aspiration, Complication of Anesthesia
- Trial name
- NCT05360810
- Testing
- Wei Nasal Jet Tube, Gastro Laryngeal Tube
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Bezmialem Vakif University
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Infant, Premature
Automated Oxygen Control in Preterms on Non-invasive Ventilation
This randomised controlled trial aims to investigate the effectiveness of closed-loop automated oxygen control (CLAC) in preterm infants receiving non-invasive respiratory support and determine if it reduces the duration of…
- Conditions
- Infant, Premature, Airway Morbidity
- Trial name
- NCT07622563
- Testing
- Closed loop automated oxygen control
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- King's College Hospital NHS Trust
Anesthesia Intubation Complication, Difficult Intubation
Safety and Efficacy of Cleverscope. A New Medical Device for Tracheal Intubation
Cleverscope is a new medical device that transform a laryngoscope into a videolaryngoscope. previous its commercialization we evaluate its safety and efficacy.
- Trial name
- NCT03902704
- Testing
- Cleverscope, Laryngoscope / Videolaryngoscope C-MAC® Storz
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario de Valencia
Critically Ill, Ventilation Therapy; Complications
Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients--Protocol for a Delphi Study
Intubated critically ill patients are susceptible to secretion accumulation because of compromised airway clearance. Various airway clearance interventions are employed to prevent complication(s) arising from mucus retention.
- Conditions
- Critically Ill, Ventilation Therapy; Complications, Mucus Retention, Airway Clearance Impairment
- Trial name
- ACCorDingly (NCT06649734)
- Testing
- Delphi Study
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Postoperative Period, Physical Therapy Modalities
Positive Pressure Therapy to Optimize LUNG Function After Heart Surgery
The most common cardiac surgeries are myocardial revascularization and valve replacement or plastic surgery. In the postoperative period of cardiac surgeries, the incidence of pulmonary complications ranges from 30% to 50% and is…
- Conditions
- Postoperative Period, Physical Therapy Modalities, Continuous Positive Airway Pressure, Respiratory Function Tests
- Trial name
- PRO-LUNGHS (NCT06611527)
- Testing
- PS+PEEP group, CPAP group
- Where
- Brazil
- Volunteers
- 156 people
- Sponsor
- Federal University of São Paulo