Clinical trials: Airway Assessment
Chronic Obstructive Pulmonary Disease, Lung Disease Causing Persistent Narrowing of the Airways
AZD2115 Single Ascending Dose Study
AZD2115 Single Ascending Dose Study
- Trial name
- NCT01283984
- Testing
- AZD2115
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma
Airway Hyper-responsiveness Study In Asthma Using Salmeterol/Fluticasone Propionate Combination Product
This double-blind, stratified, parallel group study is to determine whether aiming for 'Total control' results in better airway hyper-responsiveness than maintaining the treatment level at which 'Well-controlled' asthma was…
- Trial name
- NCT00291382
- Testing
- Salmeterol/fluticasone propionate combination
- Where
- 35 sites in Belgium, Estonia and 8 more
- Volunteers
- 150 people
- Sponsor
- GlaxoSmithKline
Obstructive Sleep Apnoea
The Use of Oral Appliances as an Adjunct to Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnoea
This study will look at whether patients with OSAHS already successfully treated with nasal CPAP could successfully use an oral appliance as a short-term treatment alternative and whether patients who could use an oral appliance…
- Trial name
- NCT00358605
- Testing
- The Klearway™ oral appliance
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Upper Respiratory Tract Infection, Nasal Congestion and Inflammations
Examination of the Effectiveness of Nasal Irrigation Techniques in Infants With Nasal Congestion
The research investigates the effects of high-volume and low-volume nasal irrigation techniques applied to relieve nasal congestion in infants with nasal congestion due to upper respiratory tract infections.
- Trial name
- NCT06002594
- Testing
- group low-volume irrigation, group high-volume irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Airway Assessment
Ultrasonographical Assessment of Airway Indices in Pregnancy
Clinical and ultrasound indices of airway, in addition to laryngoscopic view will be assessed and compared among three groups of patients: non pregnant, pregnant with normal blood pressure, preeclampsia patients undergoing…
- Trial name
- NCT07423741
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- South Valley University
Obstructive Sleep Apnea Syndrome
Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Continuous Positive Airway Pressure (CPAP) is the standard treatment in patients with Obstructive Sleep Apnea Syndrome (OSAS). The goal of the study is to evaluate CPAP treatment duration recorded by the AL539 during attended…
- Trial name
- AL539 (NCT01441622)
- Testing
- AL539 (SRETT)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Air Liquide Santé International
Postoperative Airway Complications
The Impact of Endotracheal Cuff Pressure Assessment Using a Cuff Pressure Manometer Compared With the Traditional Palpation Method on Postoperative Outcomes
The aim of this prospective observational study is to evaluate the effect of endotracheal cuff pressure management on postoperative complications in patients undergoing surgery under general anesthesia.
- Trial name
- ECP (NCT07427173)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Asthma, Allergic Rhinitis
Assessment of Oxidative Stress Markers in the Upper and Lower Airways of Atopic Children Treated With Nebulized Beclomethasone
Although it is well known that the presence of uncontrolled inflammation in upper airways may compromise the control of asthma and may favor the progression of asthma toward more severe grades of disease, few studies addressed…
- Trial name
- NCT01113489
- Testing
- beclomethasone dipropionate
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy
Focus: Localizing the Cricothyroid Membrane Before Airway Management
Ultrasound Examination Versus Palpation to Locate the Cricothyroid Membrane
Anesthesiologists get a course on localizing the cricothyroid membrane on a human using ultrasonography. Thereafter their ability to localize the cricothyroid membrane with either palpation or ultrasonography, in a randomised…
- Trial name
- NCT01735760
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COPD
Prospective Exploratory Study to Assess the Effects of the AlphaCore® Device in Patients With COPD
Title: Open-label, prospective exploratory study to assess the effects of the AlphaCore® device on central and peripheral airway dimensions in patients with COPD.
- Trial name
- NCT01720680
- Testing
- Low dose multislice CT thorax, AlphaCore® device
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- University Hospital, Antwerp
Asthma
Study of Inhaled ARO-RAGE in Allergen-induced Mild Asthma
The purpose of this study is to evaluate the impact of inhaled ARO-RAGE on the late asthmatic response (LAR) following an inhaled allergen challenge in participants with mild atopic asthma.
- Trial name
- NCT07241546
- Testing
- ARO-RAGE
- Where
- 6 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Arrowhead Pharmaceuticals
Bronchial Asthma
A Study to Assess Jia Wei Yang He Formula as a Plus Therapy in the Treatment of Persistent Asthma
Investigators aimed to assess Jia Wei Yang He Formula as a plus therapy in the treatment of persistent asthma and to explore Airway Microbiome variation of Asthma by Traditional Chinese Medicine treatment
- Trial name
- NCT03299322
- Testing
- Jia Wei Yang He granule
- Where
- 8 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease
Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38)
The purpose of this study is to evaluate the efficacy, safety and tolerability of aclidinium bromide doses compared with placebo in the treatment of moderate to severe, stable chronic obstructive pulmonary disease.
- Trial name
- LAS-MD-38 (NCT01045161)
- Testing
- Aclidinium bromide
- Where
- 112 sites in United States, Canada
- Volunteers
- 544 people
- Sponsor
- AstraZeneca
Airway Management, Tracheal Intubation
Evaluation of SaCoVLM™ Video Laryngeal Mask for Airway Management in Military Medics
A prospective, two-phase interventional study evaluating the performance, safety, and usability of the SaCoVLM™ video laryngeal mask airway for airway management by military medics with limited intubation experience.
- Conditions
- Airway Management, Tracheal Intubation, Anesthesia
- Trial name
- SAVER (NCT07249983)
- Testing
- SaCoVLM™ Video Laryngeal Mask
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Obstructive Sleep Apnea
Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness
In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.
- Trial name
- Muscle-OSA (NCT06334601)
- Testing
- Tests of upper airway collapsibility and muscle responsiveness.
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Auxologico Italiano
Airway Management, Point of Care
Upper Airway Ultrasound Evaluation
Current guidelines support the use of predictive clinical tests in the evaluation of difficult airway, meaning either difficult bag and mask ventilation, conventional laryngoscopy and/or endotracheal intubation.
- Conditions
- Airway Management, Point of Care, Ultrasound
- Trial name
- NCT06701253
- Testing
- point of care ultrasound
- Where
- Greece
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
ARDS, COVID19
Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS
The 2020 pandemic of the coronavirus (SARS-CoV2) has lead to an increase in ARDS cases requiring invasive mechanical ventilation in the ICU (Intensive Care Unit).
- Trial name
- APRV-COVID19 (NCT04386369)
- Testing
- Airway pressure release ventilation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Central Hospital, Nancy, France
Idiopathic Pulmonary Fibrosis, Small Airways Disease
Small Airways Disease Functional Assessment in Idiopathic Pulmonary Fibrosis (SWIFT-IPF)
Idiopathic Pulmonary Fibrosis (IPF) is a chronic, fibrosing, and progressive lung disease of unknown cause, whose incidence increases proportionally from the age of 60. It is characterized by a poor prognosis.
- Trial name
- SWIFT-IPF (NCT07312305)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Milan
Acute Respiratory Distress Syndrome
Expiratory Flow Limitation Assessment
This study intended to assess the expiratory flow limitation (EFL) during tidal breath in patients intubated in intensive care unit (ICU) for moderate or severe acute respiratory distress syndrome (ARDS).
- Trial name
- FLAIR (NCT03462849)
- Testing
- increase in positive end expiratory pressure
- Where
- 2 sites in France
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Lung; Node
Airway Navigation Database Asia for Diagnosis of Peripheral Pulmonary Nodules
The study is designed to evaluate the efficacy and safety of Augmented Reality Navigation System through intra-airway navigation system to guide bronchoscopy in the diagnosis of peripheral pulmonary nodules and explore the…
- Trial name
- ANDA (NCT04740606)
- Testing
- Augmented Reality Navigation System
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Guangzhou Institute of Respiratory Disease