Clinical trials: Air Pollution
Air Pollution, Cardiometabolic Health
HEPA, PM2.5, and Cardiometabolic Health
The goal of this randomized, double-blind, crossover trial is to test the hypothesis that a longer-term indoor HEPA filtration intervention can improve cardiometabolic profiles by reducing indoor PM2.5 exposures in at-risk…
- Trial name
- NCT05718245
- Testing
- HEPA filter
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Gastric Cancers, Air Pollution
The Effect of Environmental Factors on Gastric Cancer Based on Macrogenome
The objectives of this study were to clarify how environmental factors such as air pollution affect the occurrence and development of gastric cancer; to identify patient-specific macrogenomic markers of gastric cancer; and to…
- Trial name
- NCT06854146
- Testing
- gastric cancer, healthy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dong Peng
Air Pollution, Indoor
The Clean Air Study: HEPA Purifiers to Improve Indoor Air Quality and Health in Rural Alaska Homes
Alaska Native children experience a high burden of respiratory disease, especially those in the Yukon-Kuskokwim (YK) Delta. Studies have shown that things like wood stove use, poor ventilation, and indoor tobacco smoke exposure…
- Trial name
- NCT06534385
- Testing
- Air purifier
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
Sudden Unexpected Infant Death, Air Pollution, Pesticides
Environmental Exposures and Sudden Unexpected Infant Death
This project is a descriptive study designed to identify the exposure of infants who died of MIN to ambient air pollutants, and to measure pesticide concentrations in biological matrices (hair, serum, LCS) within a sample from…
- Trial name
- ExpoMIN (NCT06708793)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Climate Change, Chronic Lung Disease
Awareness of Individuals with Chronic Lung Disease About Climate Change, Heat Waves, Air Pollution and Physical Activity
Climate change is characterized by global temperature increase, melting of glaciers and increasing temperature of ocean waters. Increase in greenhouse gases such as nitrogen and carbon dioxide negatively affects air and water…
- Conditions
- Climate Change, Chronic Lung Disease, Air Pollution
- Trial name
- NCT06592235
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Air Pollution
Study to Determine the Difference in Reduction of Bioaerosols in a Long-term Care Facility
This is a CONTROLLED PROSPECTIVE COHORT study of a long-term care facility. At the start of the study a dedicated section A of the facility ventilation system will have routine HVAC filters of the same dimensions installed, while…
- Trial name
- C-PolarLTC (NCT06506890)
- Testing
- Use of C-Polar coated HVAC Filter versus conventional HVAC Filter
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- C-Polar Innovations
Emergency Service, Hospital, Air Pollution
Modelling of Correlation Between Emergency Department Admissions and Location-specific Air Quality and Weather in the Florence Urban Area
The goal of this observational study is to evaluate the impact of primary air pollutants and weather parameters on emergency department (ED) visits in the metropolitan area of Florence.
- Conditions
- Emergency Service, Hospital, Air Pollution, Weather
- Trial name
- NCT06491290
- Testing
- No intervention administered
- Where
- Italy
- Volunteers
- 480,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Air Pollution, Pollution; Exposure
Modification of Ambient Air Pollution Exposure and Cardiopulmonary Outcomes by Socioeconomic Status and Nutrition
The goal of this observational study is to compare the effects of air pollution exposure and nutrition between neighborhoods with high and low social vulnerability scores.
- Conditions
- Air Pollution, Pollution; Exposure, Nutrition, Healthy
- Trial name
- SENSE (NCT05843370)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Air Pollution
Air Pollution: Strategies for Personalized Intervention to Reduce Exposure
Fine particulate matter < 2.5 microns (PM2.5) air pollution is a leading global risk factor for cardiovascular morbidity and mortality.
- Trial name
- ASPIRE (NCT03744871)
- Testing
- N95 Respirator
- Where
- 2 sites in United States, China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Air Pollution
Health Effects of Repeated Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Volunteers
Purpose: To determine whether 3-day consecutive exposures to levels of fine particulate matter (PM2.5) that are close to the current 24-hr national standard will cause changes in inflammatory and cardiopulmonary endpoints in…
- Trial name
- NCT05323240
- Testing
- PM exposure, Filtered air exposure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. EPA Human Studies Facility
Gestational Diabetes, Diabetes Type 2
Genetics of Beta Cell Failure in Mexican Americans
This is a family based genotype-phenotype study designed to assess genetic and environmental influences on obesity, insulin resistance and beta cell function in the context of gestational diabetes.
- Conditions
- Gestational Diabetes, Diabetes Type 2, Insulin Resistance, Beta Cell Function
- Trial name
- NCT03301519
- Volunteers
- 1,250 people
- Sponsor
- University of Southern California
Air Pollution
Reducing Traffic Pollution Exposure Improves Blood Pressure
This randomized trial assessed the effect of modifying building envelop and level of air filtration on blood pressure over two hour exposure sessions.
- Trial name
- NCT04029129
- Testing
- Air filtration and building envelop modifications
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- UConn Health
Household Air Pollution, Behavior, Social
P3 Ghana Cookstove Study
Background: Despite their potential health and social benefits, adoption and use of improved cookstoves has been low throughout much of the world.
- Trial name
- P3 (NCT03617952)
- Testing
- P3 Bio Intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Air Pollution, Pregnancy
Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution Exposure
The purpose of this project is to study the effects of air pollution toxicants on pregnant mothers' immune health during and after pregnancy.
- Trial name
- NCT04549142
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Stanford University
Community-acquired Pneumonia, Air Pollution
The Impact of Air Pollution on the Consumption of Antimicrobials in the General Population
Objectives: To test the hypothesis that certain levels of air pollution may lead to increases in 1) antimicrobial consumption in the general population and 2) the presence of antibiotic resistance genes.
- Conditions
- Community-acquired Pneumonia, Air Pollution, Drug Resistance, Microbial
- Trial name
- ONAIR (NCT04662047)
- Where
- Spain
- Volunteers
- 3,249,128 people
- Sponsor
- Hospital Universitari de Bellvitge
Health Effects of Ambient Air Pollution
Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults
This observational study recruits healthy individuals who have been routinely taking high amount (at least 3 g/wk) of dietary eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and those who don't, and examines the…
- Trial name
- PISCES (NCT02921048)
- Testing
- omega-3 fatty acids
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- U.S. EPA Human Studies Facility
COPD Exacerbation, Air Pollution
Salvational Intervention for Reducing AECOPD Under Severe Air Pollution
This is a multi-center, prospective, randomized and standard treatment parallel control clinical trial.A total of 764 stable COPD patients according to GOLD will be recruited and equally divided into two parallel groups…
- Trial name
- SIRCAP (NCT03083067)
- Testing
- Budesonide/formoterol, tiotropium bromide
- Where
- 11 sites in China
- Volunteers
- 402 people
- Sponsor
- Peking University First Hospital
Exercise-induced Bronchoconstriction, Air Pollution
Exercise in Air Pollution and Lung Health in Asthmatics
When exposed to air pollution, the asthma symptoms are aggravated and lung function is impaired. Due to high breathing rates and volumes, physically active individuals are at particular risk of lung health impairment due to the…
- Trial name
- NCT02252302
- Testing
- Rest (Sitting on chair), Cycling exercise, Salbutamol inhalation
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia