Clinical trials: Agreement
Hematopoietic Stem Cell Transplantation, Graft Versus Host Disease
Cyclosporine Dose Adjustment According to Calcineurin Activity After Allogeneic Hematopoietic Stem-cell Transplantation
The purpose of this trial is to assess whether an adaptation of cyclosporine (CsA) dose according to a longitudinal calcineurin (CN) activity monitoring would prevent the onset of graft-versus-host disease (GVHD).
- Trial name
- CALCICLO (NCT00948727)
- Testing
- Dose adaptation according to CN activity monitoring, Cyclosporine (CsA)
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-small Cell Lung Cancer
The Accuracy of Targeted Lymph Node Dissection of Non-small Cell Lung Cancer Patients According to Predictive Models
Investigators combined the clinical and radiomics characteristics of resectable non-small cell lung cancer patients to construct an accurate model for preoperative prediction of mediastinal lymph node status.
- Trial name
- NCT06768853
- Testing
- Lymph node dissection based on the guidelines, Lymph node dissection based on the model
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhongnan Hospital
Caudal Block for Postoperative Analgesia
Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile Anesthesia
Caudal block is commonly used for postoperative analgesia in paediatric patients. A higher volume (1.5 ml/kg) of local anaesthetic for caudal block has been reported to not only increase the level of cranial spread but also…
- Trial name
- NCT04415905
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Type 2
A Concordance Study Comparing Insulin Treatments in Patients With Type 2 Diabetes
A study to compare insulin use and its effect on glucose control and other outcomes in patients with Type 2 diabetes who together with their healthcare provider manage their disease by discussing and agreeing on the diabetes…
- Trial name
- NCT00330473
- Testing
- Human Insulin Inhalation Powder, Insulin
- Where
- 60 sites in United States, Argentina and 10 more
- Volunteers
- 1,019 people
- Sponsor
- Eli Lilly and Company
Lower Extremity Problem, Delirium
Intraoperative Sedatives and Postoperative Deilirium
Delirium occurs commonly in elderly patients. Its incidence after orthopedic surgery has been reported to be 5-61%. Delirium is classified into three sub-types: Hypoactive, hyperactive, and mixed.
- Conditions
- Lower Extremity Problem, Delirium, Propofol, Dexmedetomidine
- Trial name
- NCT03251651
- Testing
- Propofol, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 748 people
- Sponsor
- Seoul National University Bundang Hospital
Peripheral Vascular Disease
Belgian Prospective Multicentre Registry on the Performance of the Smart Stent in the Superficial Femoral Artery According to the New Tasc II-classification
This is a Belgian prospective multicentre registry on the performance of the Smart stent in the superficial femoral artery according to the new tasc II-classification.
- Trial name
- NCT00496041
- Testing
- Registry
- Where
- Belgium
- Volunteers
- 205 people
- Sponsor
- University Hospital, Ghent
Pneumonia, Ventilator-Associated
Bilateral Bronchoalveolar Lavage in Ventilator-associated Pneumonia
The purpose of this study is to assess microbiologic concordance rates between right- and left-lung bronchoalveolar lavage cultures from patients with suspected ventilator-associated pneumonia, identify predictors of concordance…
- Trial name
- NCT02542553
- Testing
- Bilateral BAL
- Volunteers
- 79 people
- Sponsor
- Catholic University of the Sacred Heart
Spinal Neoplasms, Neoplasm Metastasis
Stereotactic Body Radiotherapy Followed by Surgical Stabilization in Spinal Metastases
The aim of this study is to assess pain response after combining stereotactic body radiotherapy (SBRT) and pedicle screw fixation in a 48-hour window for the treatment of painful unstable metastases of the thoracic and/or lumbar…
- Conditions
- Spinal Neoplasms, Neoplasm Metastasis, Radiosurgery, Surgery
- Trial name
- BLEND-II (NCT05060653)
- Testing
- SBRT followed by surgical stabilization within 24-48 hours
- Where
- Netherlands
- Sponsor
- UMC Utrecht
Infections, Papillomavirus
Immunogenicity and Safety of GlaxoSmithKline Biologicals' Huma Papillomavirus (HPV) Vaccine 580299 in Healthy Females 15 - 25 Years of Age
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. The current phase 3b study is designed to assess the immunogenicity and safety of GlaxoSmithKline Biologicals' HPV…
- Trial name
- NCT00552279
- Testing
- Cervarix TM
- Where
- 16 sites in Italy, Romania and 1 more
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Hepatitis B, Hepatitis A
Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Month Schedule
The aim of this study is to evaluate the long-term persistence of hepatitis A and B antibodies at Years 11, 12, 13, 14 and 15 years after subjects received their first dose of a 3 dose vaccination schedule of combined hepatitis…
- Trial name
- NCT00289718
- Testing
- Twinrix™ adult
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Breakthrough Cancer Pain
Treatment of Breakthrough Cancer Pain According to European Guidelines
Pain is a frequent symptom in cancer patients with a negative impact on the quality of life (QoL).Breakthrough cancer pain (BTcP) is defined as "a transient exacerbation of pain, manifesting spontaneously or related to a specific…
- Trial name
- BEG (NCT04468490)
- Where
- Poland
- Volunteers
- 131 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Neuromuscular Disorders, Chest Wall Disorders
Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern
The purpose of this study is to determine whether breathing pattern (specifically the inspiratory time/total respiratory cycle value) has an influence over the response to the noninvasive mechanical ventilation.
- Conditions
- Neuromuscular Disorders, Chest Wall Disorders, Obesity Hypoventilation Syndrome (OHS)
- Trial name
- NCT01991535
- Testing
- Spontaneous Ventilation Mode, Controlled Ventilation Mode, Simulator Ventilation Mode
- Where
- Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Eye Abnormalities, Normal Eyes
The Heidelberg Engineering ANTERION Imaging Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess image quality of acquired biometry images of the eye
- Trial name
- NCT04068818
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Post Anesthesia Care Optimaization
Agreements Between Transcutaneous and Arterial Monitoring of Oxygen and Carbon Dioxide After Non-cardiac Surgery
The primary aim of the study is to describe the association between changes in TcO2 and TcCO2 and interventions such as blood transfusion, fluid therapy, respiratory support, use of vasopressors, analgesics, and adverse events…
- Trial name
- NCT04735380
- Testing
- TCM-5 Flex monitor connected to a Sensor 84 (Radiometer Medical Aps, Brønshøj, Denmark)
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Premature Birth
Evaluation of Immunization Coverage of Premature Infants Leaving CHU d'Angers According to the Recommended Regimen During the First 4 Months (VACCIPREM)
Premature children are particularly vulnerable in terms of infection and vaccinated in a specific, reinforced vaccination schedule.
- Trial name
- VACCIPREM (NCT03918096)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 384 people
- Sponsor
- University Hospital, Angers
Hip Fracture of Intertrochanteric Type, Thromboembolic Event
Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis
Hip fracture is a common and severe disease in elderly patients. The question of the study is whether elderly patients with severe osteopenia have significantly lower levels of the collagen-binding protein Hsp47 than relatively…
- Conditions
- Hip Fracture of Intertrochanteric Type, Thromboembolic Event, Osteopenia, Thrombosis Embolism
- Trial name
- HSP 47 (NCT06959017)
- Testing
- Gene Expression Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Sjögren's Syndrome
Efficacy and Safety of Belimumab in Primary Sjögren's Syndrome
Background and rationale Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by chronic inflammation of salivary and lachrymal glands, frequently accompanied by systemic symptoms.
- Trial name
- NCT01008982
- Testing
- LimphoStat-B
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Udine
Mechanical Low Back Pain
Study of Effectiveness of Pold in Chronic Nonspecific Low Back Pain
Through this research is to conduct a pilot clinical trial in the treatment of chronic nonspecific low back pain (degenerative and mechanical), by comparing two groups, one that will apply a technique of physiotherapy by passive…
- Trial name
- Pold-LBP (NCT01591824)
- Testing
- Resonant oscillation, column exercise group
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Omphis Foundation
Hypertension, Dyslipidemias
A Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-386 in Healthy Male Volunteers
a study to investigate the pharmacokinetic characteristics and safety/tolerability according to formulations of CKD-386 in healthy male volunteers
- Trial name
- NCT03920579
- Testing
- CKD-386 formulation 1, CKD-386 formulation 2, D326, D337 and D013
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical