Clinical trials: Agitation
Agitation
ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in…
- Trial name
- NCT01374737
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Agitation
A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of Schizophrenia
The primary objective of this study is to evaluate the efficacy and safety of Intramuscular Levosulpiride in the treatment of Chinese patients with Agitation Of Schizophrenia compared with Intramuscular Haloperidol by evaluating…
- Trial name
- NCT00866645
- Testing
- Intramuscular Haloperidol, Intramuscular Levosulpiride
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai Mental Health Center
Akathisia, Nausea
Efficacy and Akathisia Incidence of Slow Infusion Metoclopramide
Study Objective: The purpose of this study is to compare the effects of metoclopramide administration in bolus versus slow infusion medications in ED patients complaining of nausea for the determination of the therapeutic effect…
- Trial name
- NCT01069536
- Testing
- metoclopramide 10 mg
- Volunteers
- 140 people
- Sponsor
- Pamukkale University
Akathisia
Prophylaxis Against Metoclopramide-Induced Akathisia
ABSTRACT Study Objective: To compare the effects of midazolam and diphenhydramine for the prevention of metoclopramide induced akathisia.
- Trial name
- NCT01051271
- Testing
- midazolam
- Volunteers
- 225 people
- Sponsor
- Pamukkale University
Dementia, Parkinson Disease
Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)
The primary aim of this study is to determine the safety and efficacy of quetiapine (Seroquel) for the treatment of psychosis and/or agitation in patients with primary dementia complicated by coexistent parkinsonism, or patients…
- Trial name
- NCT00043849
- Testing
- Quetiapine
- Where
- 21 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute on Aging (NIA)
Dementia, Behavior Problems
Treatment Routes for Exploring Agitation
The purpose of this study is to examine the efficacy of non-pharmacological ways to treat agitated behaviors in nursing home residents with dementia.
- Trial name
- TREA (NCT00820859)
- Testing
- TREA (Treatment Routes for Exploring Agitation)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Aging (NIA)
Pediatric Emergence Agitation and Pain
Does Distraction With a Hand Held Video Game Reduce Preoperative and Emergence Anxiety in Children?
Preoperative anxiety is characterized by subjective feelings of tension, apprehension, nervousness and worry. In children, preoperative anxiety is reported to result in postoperative negative psychological effects, including…
- Trial name
- NCT00932685
- Testing
- Midazolam, Game Boy
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Alzheimer Disease
Bathing Persons With Alzheimer's Disease aT Home (The BATH Study)
This study will evaluate the effectiveness of a 3-week reminiscence intervention applied during bathing persons with Alzheimer's disease (AD) in decreasing resistiveness to care (RTC), relieving patient discomfort, and improving…
- Trial name
- NCT00062569
- Testing
- Bathing Support Intervention (BSI), Caregiver reminiscence with coaching
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Alzheimer's Disease, Dementia
Specific Interventions for Agitation in Alzheimer's Disease
This study is aimed at investigating specific pharmacological interventions in the treatment of the disruptive, agitated behavior associated with Alzheimer's patients.
- Trial name
- NCT00018291
- Testing
- Risperidone, Gabapentin
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Agitation
Liquid Risperidone in the Treatment of Acute Agitation in Psychiatrically Hospitalized Children
The goal of this study is to demonstrate safety and efficacy of liquid risperidone in psychiatrically hospitalized children, ages 4-12, who would be put in seclusion or restraint, or given an intramuscular injection of…
- Trial name
- NCT00790075
- Testing
- risperidone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stony Brook University
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Respiratory Insufficiency, Psychomotor Agitation
Loxapine and Weaning From Ventilator
Patients may be very agitated during the weaning period from mechanical ventilation. Administration of loxapine, a neuroleptic that does not notably affect ventilatory drive, may help in obtaining an adequate level of cooperation…
- Trial name
- NCT00122733
- Testing
- loxapine
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Insufficiency, Pain
Ketamine Sedation in Mechanically Ventilated Patients
Adequate sedation is of paramount importance to avoid stress and pain in mechanically ventilated patients. It is usually achieved by infusing sedatives (benzodiazepine) and analgesic (opiate) drugs.
- Conditions
- Respiratory Insufficiency, Pain, Psychomotor Agitation
- Trial name
- NCT00122759
- Testing
- ketamine
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Agitation Aggression in Dementia
The Effect of Oxcarbazepine in the Treatment of Agitation / Aggression in Dementia (OBAD)
We intend to conduct a phase III b trial to verify Oxcarbazepine's effect in agitation and aggression in patients with dementia. We designed the study as a randomized, double-blind, placebo-controlled multi center trial.
- Trial name
- NCT00145691
- Testing
- Oxcarbazepine
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Innlandet HF
Delirium, Agitated Behavior
Trial of Safety Nets In Hospitalized Patients
This study compared standard hospital restraints to a newer safety net restraint system to compare them for acceptability, tolerance, duration of restrain, length of stay in the hospital, and satisfaction of MD, nurse, and…
- Conditions
- Delirium, Agitated Behavior, Alcohol Withdrawl, Acute Confusional State
- Trial name
- NCT00409370
- Testing
- SOMA safe enclosure
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Griffin Hospital
Dementia
Study of Depakote for Behavioral and Psychological Symptoms in Dementia
This prospective, naturalistic, open label study will test the hypothesis that Depakote is correlated with a reduction in elevated Cohen-Mansfield Agitation Index (CMAI) verbal and physical agitation and aggression scales over a…
- Trial name
- NCT00197834
- Testing
- Depakote
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hearthstone Alzheimer Care
Alzheimer's Disease, Dementia
High Intensity Light Therapy in Alzheimer's Disease
The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the…
- Trial name
- NCT00065689
- Testing
- high-intensity light therapy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Alzheimer Disease
Agitation in Alzheimer's Disease
Agitation affects 70 to 90 percent of patients with AD. Signs of agitation include verbal and physical aggressiveness, irritability, wandering, and restlessness.
- Trial name
- NCT00000179
- Testing
- Trazodone, Haloperidol
- Where
- 16 sites in United States
- Sponsor
- National Institute on Aging (NIA)
Akathisia
Akathisia (Restless Legs Syndrome) in People With Schizophrenia and Mental Retardation
Akathisia is a movement disorder that is often a side effect of certain psychiatric drugs. People with akathisia are unable to sit or keep still, complain of restlessness, fidget, rock from foot to foot, and pace.
- Trial name
- NCT00065286
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)