Clinical trials: Aging Problems
Surgery--Complications, Age Problem
Multicenter National Trial of Clinical Results of Surgical Elderly Patients
The aim of this study is to study clinical results including mrobidity and mortality of elderly patients (age > 75 years) in Spain during a 3-month period.
- Trial name
- CiruGerES: (NCT05254262)
- Testing
- Elderly surgical patients
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Germans Trias i Pujol Hospital
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Aging Problems
Effects of Improvement of the Ankle Joint Range on Balance in the Elderly.
The effects of aging on the ankle joint will contribute negatively to balance in the elderly. Manual therapy is a technique that is usually used to treat ankle arthrokinematics, although there is little literature on this…
- Trial name
- ANKLE_ROM (NCT03743857)
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Age Problem
Efficacy of the Otago Exercise Program Delivered as Group Training Versus Individually Tailored Training
A non-inferiority controlled clinical trial using randomization for allocation at the level of general practice in 21 centers (in 8 Spanish regions), to compare a group Otago exercise program (OEP) [delivered by specifically…
- Trial name
- NCT03320668
- Testing
- Otago Exercise Program (OEP)
- Where
- 9 sites in Spain
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Age Problem, Disability
Beijing Disability Risk and Ageing Monitoring Study
This is a community-based prospective cohort study in Beijing, China. The study has been initialized in 2023 and enrolled older residents.
- Conditions
- Age Problem, Disability, Death
- Trial name
- BEAM (NCT06394817)
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Aging Problems
Dose-response of Talus Mobilizations
Ankle mobility limitations are common in older adults. A possible treatment to restore joint mobility is manual therapy based on mobilization techniques, in this case, applied on the ankle joint.
- Trial name
- ANKLE_ROM (NCT04360512)
- Testing
- Posteriorization of the talus
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Memory Deficits, Mood Change
The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population
The goal of this project is to develop probiotic dietary supplements intended for the elderly, which can modify the composition of the intestinal microbiota typically occurring in the aging population.
- Conditions
- Memory Deficits, Mood Change, Gut Health, Aging Problems
- Trial name
- CleverAgeBiota (NCT05051501)
- Testing
- Probiotics C2P
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Frailty, Frailty Syndrome
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
This project aims to address the impact of frailty on older adults, particularly its connection to cognitive impairments such as dementia.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Pre-Frailty
- Trial name
- NCT05961319
- Testing
- Smart-Home Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Age Problem, Aortic Valve Disease
Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders
In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and…
- Conditions
- Age Problem, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- FRASER-VD (NCT03365453)
- Testing
- frailty evaluation
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- University Hospital of Ferrara
Aging Problems, Caregiver
GUARDIAN: The Social Robot Companion to Support Homecare Nurses
The primary objective of this study is to verify the acceptability of the GUARDIAN system by the elderly, detected through the scale Unified Theory of Acceptance and Use of Technology (UTAUT).
- Trial name
- GUARDIAN (NCT05284292)
- Testing
- GUARDIAN platform
- Where
- 3 sites in Italy, Netherlands and 1 more
- Volunteers
- 30 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Age Problem
Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults
The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.
- Trial name
- NCT04658225
- Testing
- 0.12% chlorhexidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Aging, Aging Problems
Brain Health Virtual Reality Study
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa.
- Conditions
- Aging, Aging Problems, Memory Loss, Memory Impairment
- Trial name
- NCT06124339
- Testing
- Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Age Problems
Evaluation of the PPAL
This research study is being conducted to better understand the impact of the PPAL assisted toileting device. The PPAL consists of a powered, height-adjustable commode chair with integrated transfer boards.
- Trial name
- NCT07221552
- Testing
- PPAL
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Alicia Koontz
Aging Problems, Balance; Distorted
Comparison of the Effects of Different Living Environments in Geriatric Individuals: A Pilot Study
In Turkey, 63% of geriatric people who make up approximately 8.3% of the entire population live in their own living environment, 36% live with their children and 1% live in nursing homes.
- Conditions
- Aging Problems, Balance; Distorted, Pain, Quality of Life
- Trial name
- NCT04873791
- Testing
- Assessment of geriatric individuals living in home environment and nursing home.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Chronic Pain, Physical Activity
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
The investigators aim to conduct a randomized controlled trial to compare two symptom-management programs for Black older adults with early cognitive decline (self-reported confirmed by testing) and chronic pain.
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Trial name
- HABIT (NCT06246929)
- Testing
- MBCT+w, ALED
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Problem of Aging
Volume Restoration of the Aging Midface With Sculptra Aesthetic
The purpose of this study is to examine the effect of Sculptra Aesthetic on the cosmetic rejuvenation of the midface complex. The investigators plan to both qualitatively determine the restoration of midface architecture as well…
- Trial name
- NCT01307865
- Testing
- injectable poly-L-lactic acid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Williams Center Plastic Surgery Specialists
Sleep, Cognitive Impairment
Observational Study About Sleep Quality and Its Impact on Daily Life of Nursing-home Residents
Introduction: Poor sleep quality is common in most older adults. Because of the progressive aging of the population in Spain, there are more and more nursing-home and day centers, which give care to older adults.
- Conditions
- Sleep, Cognitive Impairment, Quality of Life, Age Problem
- Trial name
- NCT04592796
- Testing
- Xiaomi MiBand2, Socio-demographic questionnaire, EuroQol-5D-5L
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Universidade da Coruña
Aging Problems, Wrinkle
Comparing Polydioxanone Thread Embedding Acupuncture and Manual Acupuncture for Nasolabial Fold Reduction
This study was aimed to compare the effectiveness of polydioxanone thread embedding acupuncture and manual acupuncture on the reduction of the nasolabial fold.
- Trial name
- NCT05098912
- Testing
- Manual acupuncture, Thread embedding acupuncture
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Aging Problems
Effect of Floorball on Healthy Subjects
To investigate the effect of floorball on health and performance in healthy subjects over 65 years.
- Trial name
- NCT03371238
- Testing
- Floorball
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen