Clinical trials: Aging Problems
Depression
Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)
The objective of this study is to evaluate the ability of a behavioral intervention, cognitive behavioral therapy for sleep quality (CBT-SQ) to reduce sleep complaints, depression recurrence, and cellular and genomic markers of…
- Trial name
- PRO-SHARE (NCT01641263)
- Testing
- Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Disease, Aging
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion
The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.
- Conditions
- Chronic Disease, Aging, Aging Problems, Health Behavior
- Trial name
- NCT04492527
- Testing
- Telehealth coaching sessions
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aging Problems
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 26 Dermal Filler for Cheek Augmentation
This is a pivotal, prospective, active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 26 versus Juvederm…
- Trial name
- NCT05021926
- Testing
- DKL crosslinked sodium hyaluronate 26, Juvéderm Voluma™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Insulin Resistance, Age Problems
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.
This study intends to examine the effect of a commercially available nutritional supplement, Beta-hydroxy-beta-methylbutyrate(HMB) on whole-body responses to a sugar load.
- Trial name
- NCT03018496
- Testing
- Beta-Hydroxy-Beta-Methylbutyrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Age Problem
Falls Risk Awareness Video Study
The primary aim of this study is to develop and evaluate three short corporate falls risk awareness videos of approximately 1-2 minutes (each) by using the feedback from community-dwelling people aged 50 years and above.
- Trial name
- NCT03154788
- Where
- Australia
- Volunteers
- 92 people
- Sponsor
- Curtin University
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Acute Coronary Syndrome, Age Problem
Determining the Age of First Acute Coronary Syndrome
The study aimed to evaluate the association between the obesity grade and the age of the first acute coronary syndrome (ACS). The effect of cardiovascular (CV) risk factors and the age of first ACS in patients with severe obesity…
- Conditions
- Acute Coronary Syndrome, Age Problem, Risk Factor, Cardiovascular
- Trial name
- NCT04578964
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Antalya Training and Research Hospital
Aging Problems
Evaluation of the EEG Connectivity Using Predominant Dexmedetomidine as Anesthetic in Fragile Brains
Elderly brains that present a lower intrinsic cortical activity are very dependent on arousal feeding. In these patients, a strong blockade of afferences generates a synchronic state with a high tendency to sleep.
- Trial name
- BaseDexmed (NCT05425069)
- Testing
- Comparison MoCA test and EEG connectivity pre, intra and postoperative between groups P vs D-P
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Age Problem
Digital Support for Quality Assurance in 24-hour Caregiving at Home
Due to the demographic change, there is a growing demand for professional and institutional care, as well as the need for 24-hour home care.
- Trial name
- 24h-quAALity (NCT04581538)
- Testing
- Intervention of parallel arm 2, Intervention of parallel arm 3
- Where
- 4 sites in Austria
- Volunteers
- 72 people
- Sponsor
- Peter Putz
Age Problem, Morality
Use of Device Data to Predict Frailty in Individuals
This is an investigation to examine the correlation and predictive ability of activity measures obtained from cardiovascular implantable electrical devices.
- Conditions
- Age Problem, Morality, Arrhythmias, Cardiac
- Trial name
- FRAILCIED (NCT03079726)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Sarcopenia, Frailty
Implementation of ProMuscle in Daily Practice
Implementation of a previously shown (cost-)effective combined lifestyle intervention for community living older adults, ProMuscle, in at least four of the eight communities of the 'Foodvalley' in the Netherlands.
- Conditions
- Sarcopenia, Frailty, Aging Problems
- Trial name
- PUMP-fit (NCT05672004)
- Testing
- PUMP-fit strategy (implementation toolbox), Implementation as usual
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Age Problem, Dialysis; Complications
Twice vs Thrice Weekly Incident Hemodialysis in Elderly Patients
As Korea is becoming a super-aged society, the number of elderly patients with end-stage kidney disease (ESKD) is expected to increase rapidly. Therefore, the burden on Korean society will also increase.
- Conditions
- Age Problem, Dialysis; Complications, Frailty, Quality of Life
- Trial name
- NCT06141798
- Testing
- Hemodialysis
- Where
- 7 sites in South Korea
- Volunteers
- 428 people
- Sponsor
- Soonchunhyang University Hospital
Substance Use Disorders, Opioid Use Disorder
Substance Use and Lifestyle-related Health Problems in Ageing Patients in OMT Treatment
The overall aim of the study is to explore substance use, tobacco use and lifestyle-related health problems among ageing patients in Opioid Maintenance Treatment (OMT), and other SUD treatment.
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Tobacco Use, Health, Subjective
- Trial name
- AgeSUD (NCT05182918)
- Testing
- Substance use disorder treatment
- Where
- Norway
- Volunteers
- 548 people
- Sponsor
- Sorlandet Hospital HF
Rehabilitation, Aging Problems
Plantar Fasciitis Management on Postural Control
Foot pain is common in the general population. Plantar fasciopathy may affect 7% of the population at some time in their lives, but the incidence increases with age.
- Conditions
- Rehabilitation, Aging Problems, Foot Diseases, Mobility Limitation
- Trial name
- NCT06172517
- Testing
- Orthosis intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Université du Québec à Chicoutimi
Aging Problems, Pigmentation
16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
The objective of this study is to determine the efficacy of seven different formulations currently marketed and commercially available cosmetic products on skin tone evenness, post-inflammatory hyperpigmentation, and discrete…
- Trial name
- NCT05160103
- Testing
- Cosmetic Formulations
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Avon Products, Inc.
Aging Problems
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults
Exercise is the cornerstone of disease prevention and often an important component of treatment. However, the efficacy of an exercise stimulus is reduced with aging.
- Trial name
- NCT04848792
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Musculoskeletal Diseases, Chronic Disease
New Clinical Rehabilitation Approach for the Management of Falls Risks
Accidental falls in older adults are one of the world's major pubic health problem, because of their strong association with injuries and mortality rates.
- Conditions
- Musculoskeletal Diseases, Chronic Disease, Fall Patients, Aging Problems
- Trial name
- ReabFalls (NCT06175871)
- Testing
- OTAGO exercises
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Université du Québec à Chicoutimi
Metabolic Diseases, Aging Problems
Brain Substrate Switch to Ketones and Lactate
The brain is constantly active and energetically expensive, making up a quarter of the body's energy budget despite occupying only 2% of its mass.
- Trial name
- BSS (NCT06000605)
- Testing
- Fed, Fasted
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Men, Age Problem
Register of Therapeutical Patients Over 60 Years
Register for the study of the prevalence and burden of diseases, risk factors and outcomes of hospitalizations in older age groups in the countries of Eurasia.
- Conditions
- Men, Age Problem, Therapeutic Alliance
- Trial name
- ASCLEPIUS (NCT04295057)
- Testing
- Non-intervention
- Where
- Russia
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Eurasian Association of Therapists
Weight, Body, Smoking
Flavor Test Results in General Population
Dietary choices are influenced by several factors, including physiological, social or genetic factors. Among these, flavor is the most important determinant modulating the preferences versus specific foods.
- Conditions
- Weight, Body, Smoking, Age Problem
- Trial name
- NCT03506074
- Testing
- Flavor test
- Volunteers
- 420 people
- Sponsor
- Federico II University