Clinical trials: Aging Problems
Older Adults, Age Problem
Influence and Relationships Between Square-stepping Exercise and Brain Activation, Cognitive Function, Physical Performance in Healthy Older Adults
Background and purposes: Square-stepping exercise (SSE) has been proved to be an effective intervention for motor and cognitive function in older adults. However, the underlying mechanism of SSE still remains undetermined.
- Trial name
- NCT05891574
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Aging Problems
Effect of a New HA Filler in Correcting Nasolabial Fold
The investigators aimed to evaluate the efficacy and safety of new HA filler for nasolabial fold correction
- Trial name
- NCT06574750
- Testing
- CUREAⓇ (ARIBIO, Ltd., Seoul, Republic of Korea), JuvedermⓇ (Q-Med AB, Uppsala, Sweden)
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Aging Problems, Coordination Impairment
Effects of Jaques-Dalcroze Eurhythmics Program on Postural Stability in Elderly Women.
This study investigated the effect of exercise using the Emil Jaques-Dalcroze's method on the postural stability of women over 65 years of age. The study model was based on a randomized controlled trial - parallel group design.
- Trial name
- NCT05015777
- Testing
- Emil Jaques-Dalcroze's Eurhythimcs Exercise Program
- Where
- Poland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Aging
Studying the Impact of a Medication Use Evaluation by the Community Pharmacist
In this intervention study, 75 Belgian community pharmacies each recruit 12 patients for an intermediate medication review. For each patient, the identified drug-related problems and subsequent interventions are registered using…
- Trial name
- SIMENON (NCT03179722)
- Testing
- Medication review, Additional data collection: questionnaires
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Joke Wuyts
Lewy Body Disease, Healthy Aging
Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment
Lewy body diseases (LBDs) represents a group of neurodegenerative disorders characterized by the abnormal accumulation of aggregates of α-synuclein protein leading to the formation of Lewy bodies (LB) and Lewy neurites resulting…
- Trial name
- LANG-LBD (NCT05847985)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Dyslexia, Aging Problems
Neuroplasticity of Multisensory Cortical Areas Induced by Musical Training: a Translational Approach (MusicPlast)
Exploiting recent methodological advancements, several neuroimaging studies suggested that multisensory integration emerges from a dynamic interplay of distributed regions operating in large-scale networks.
- Trial name
- MusicPlast (NCT03786185)
- Testing
- MusicPlast, MusicPlast Control
- Where
- Greece
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Memory Problems
Brain Fitness APP for Aging With a Healthy Brain
Memory and cognitive declines are associated with normal brain aging but are also precursors to dementia, in particular the so called the pandemic of the century, Alzheimer's disease.
- Trial name
- NCT03600545
- Testing
- Brain Fitness App
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Age Problem
The SUMAMOS EXCELENCIA Project: Assessment of Implementation of Best Practices in a National Health System
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Trial name
- NCT03725774
- Testing
- GRIP (Getting Research into Practice) model
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Aging Problems
Effectiveness of the Pilates Method to Prevent and Reduce Falls in Older People
The present research aims at evidencing the effect of one of the training methodologies increasingly demanded by the older adult, and used to promote, maintain and enhance physical and biopsychosocial aspects.
- Trial name
- NCT03299374
- Testing
- Pilates Intervention, Fall prevention intervention
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cognitive Impairment, Aging Problems
Effectiveness of a Strength Program Over Cognitive Functionality in Older Adults
This is a randomized, parallel, double-blind clinical trial. The main objective is to compare the efficacy of strength training, multimodal exercise with non-specific exercises and a control group on cognitive functionality and…
- Trial name
- NCT06434857
- Testing
- Strength training in older adults with mild or non existent cognitive impairment, Multimodal excercise in older adults with mild or non existent cognitive impairment
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Cognitive Impairment, Dementia
Hainan Community Cognition Cohort
This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up.
- Conditions
- Cognitive Impairment, Dementia, Age Problems
- Trial name
- NCT06686186
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hainan Medical College
Depression
Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)
The objective of this study is to evaluate the ability of a behavioral intervention, cognitive behavioral therapy for sleep quality (CBT-SQ) to reduce sleep complaints, depression recurrence, and cellular and genomic markers of…
- Trial name
- PRO-SHARE (NCT01641263)
- Testing
- Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Disease, Aging
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion
The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.
- Conditions
- Chronic Disease, Aging, Aging Problems, Health Behavior
- Trial name
- NCT04492527
- Testing
- Telehealth coaching sessions
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aging Problems
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 26 Dermal Filler for Cheek Augmentation
This is a pivotal, prospective, active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 26 versus Juvederm…
- Trial name
- NCT05021926
- Testing
- DKL crosslinked sodium hyaluronate 26, Juvéderm Voluma™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Insulin Resistance, Age Problems
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.
This study intends to examine the effect of a commercially available nutritional supplement, Beta-hydroxy-beta-methylbutyrate(HMB) on whole-body responses to a sugar load.
- Trial name
- NCT03018496
- Testing
- Beta-Hydroxy-Beta-Methylbutyrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Aging Problems
Evaluation of the EEG Connectivity Using Predominant Dexmedetomidine as Anesthetic in Fragile Brains
Elderly brains that present a lower intrinsic cortical activity are very dependent on arousal feeding. In these patients, a strong blockade of afferences generates a synchronic state with a high tendency to sleep.
- Trial name
- BaseDexmed (NCT05425069)
- Testing
- Comparison MoCA test and EEG connectivity pre, intra and postoperative between groups P vs D-P
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Sarcopenia, Frailty
Implementation of ProMuscle in Daily Practice
Implementation of a previously shown (cost-)effective combined lifestyle intervention for community living older adults, ProMuscle, in at least four of the eight communities of the 'Foodvalley' in the Netherlands.
- Conditions
- Sarcopenia, Frailty, Aging Problems
- Trial name
- PUMP-fit (NCT05672004)
- Testing
- PUMP-fit strategy (implementation toolbox), Implementation as usual
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Aging Problems, Pigmentation
16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
The objective of this study is to determine the efficacy of seven different formulations currently marketed and commercially available cosmetic products on skin tone evenness, post-inflammatory hyperpigmentation, and discrete…
- Trial name
- NCT05160103
- Testing
- Cosmetic Formulations
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Avon Products, Inc.