Clinical trials: Ageing
Facial Aging
Laser Spot Treatment of Perioral Rhytids
Perioral rhytides present a difficult problem in facial rejuvenation. They cannot be addressed with rhytidectomy (face lift) and direct excision can leave visible unfavorable scars.
- Trial name
- NCT01986634
- Testing
- Laser Treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Multiple Sclerosis, Parkinson Disease
Gait and Balance Impairment in Rare and Very Rare Neurological Diseases
Rare and very rare neurological diseases primarily or exclusively affect the nervous system with a prevalence of < 5 out of 10'000 and 100'000 people, respectively.
- Conditions
- Multiple Sclerosis, Parkinson Disease, Peripheral Neuropathy, Rare Diseases
- Trial name
- GALVANISE (NCT06343558)
- Testing
- Questionnaires, clinical scales and instrumental tests
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Aging, Heart Failure
The COmPLETE Study
The project is designed as a large scale, cross-sectional study. This research seeks to identify physical fitness and cardiovascular parameters that best resemble underlying cardiovascular risk with age.
- Trial name
- COmPLETE (NCT03986892)
- Testing
- Physical Activity
- Where
- Switzerland
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Arno Schmidt-Trucksäss
Chronic Conditions, Multiple, Aging
Physical Literacy and Rehabilitation
With the aging population, the prevalence of chronic conditions continues to rise, affecting 1/3 of Canadians. The promotion of physical literacy, defined as "the motivation, confidence, physical competence and knowledge, to take…
- Conditions
- Chronic Conditions, Multiple, Aging, Mobility Limitation
- Trial name
- NCT04494711
- Testing
- Physical Functional Literacy for Adults
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julie Richardson
Social Isolation, Loneliness
Engage Coaching for Latinos
This study asks: "what behavioral strategies are needed to help socially disconnected Hispanic/Latino caregivers with significant barriers to increasing connectedness?" This study uses a mixed methods approach to adapt a brief…
- Conditions
- Social Isolation, Loneliness, Caregiver Burnout
- Trial name
- NCT04875065
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Aging Problems
Enhancing Care of the Aged and Dying in Prisons Ph II
The mission of corrections is to provide custody, control and care for incarcerated individuals. United States prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- NCT03055429
- Testing
- Full Scale Unit
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Hiv, Aging
Evaluating the Impact of Incentives on Clinical Trial Participation
The objective of this study is to investigate the impact of incentives on clinical trial participation. 1) characterize key stakeholders' views on and assessment of incentives, 2) reach consensus among stakeholders on the factors…
- Conditions
- Hiv, Aging, Incentives
- Trial name
- NCT04809636
- Testing
- This is not an interventional study
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Skin Aging, Photoaging
Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study
The goal of this clinical trial is to learn if retinaldehyde cream improves the appearance of aging skin in women aged 30 to 60 years.
- Trial name
- NCT07510165
- Testing
- Stabilized retinaldehyde 0.1%, Stabilized retinaldehyde 0.05%
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Insulin Resistance, Healthy
Dynamic Connectivity Under Metabolic Constraints
In this study, we investigate the impact of insulin resistance on the acceleration of brain aging, and test whether increased neuron insulin resistance can be counteracted by utilization of alternate metabolic pathways (e.g.…
- Conditions
- Insulin Resistance, Healthy, Diet Modification, Aging
- Trial name
- NCT04840095
- Testing
- Ketones, Glucose
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hemodynamics
The Effect of Age on the Hemodynamic Response During Rest and Exercise in Healthy Humans
Primary: To observe how hemodynamic parameters are affected by age during rest and exercise in healthy humans. Furthermore, how an acute fluid challenge changes hemodynamic parameters.
- Trial name
- HemReX (NCT01974557)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Finn Gustafsson
Aging
Ergospirometric Values and WBV in Elderly
this study aims evaluate the ergospirometric values after 03 months of training with WBV in elderly health people. The hypothesis is increases of ergospirometric values.
- Trial name
- EVAWIE (NCT01681719)
- Testing
- WBV and Resistance
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study
his study aims to investigate whether Osteopathic Manipulative Treatment (OMT) affects cerebrospinal fluid (CSF) flow and glymphatic clearance in the human brain.
- Trial name
- NCT07629765
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Quality of Life, Aging
Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults
The investigators propose a person-directed, values-based digital literacy intervention to address the community-identified barriers of health literacy, health communication and social support to improve quality of life and…
- Conditions
- Quality of Life, Aging, Technology, Literacy
- Trial name
- NCT06479707
- Testing
- Digital Literacy Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Hearing Loss, Cochlear Hearing Loss
Peripheral and Central Influences on Auditory Temporal Processing & Speech Perception in Older Cochlear Implantees
Older adults who use cochlear implants to address hearing loss show wide variation in benefit. This research investigates the role of normal aging, the health of peripheral and central auditory pathways, and positioning of the…
- Conditions
- Hearing Loss, Cochlear Hearing Loss, Hearing Loss, Sensorineural, Aging
- Trial name
- NCT05554692
- Testing
- Diagnostic tests of cochlear implant function, Diagnostic tests of auditory function
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Maryland, College Park
Aging, Stroke
Precision Vibration Therapy for Neuromuscular and Functional Improvement in Older Adults and Stroke Survivors
To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular…
- Trial name
- NCT07351877
- Testing
- Precision Vibration Therapy, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Health Research Institutes, Taiwan
Effect of Aging on Postural Stability
Effect of Aging on Postural Stability
Postural control of human body is a complex process involving visual , vestibular, somatosensory system and their central processing , add the vestibular system through its multiple connection coordinates movements of the head…
- Trial name
- NCT05544630
- Testing
- computerized dynamic posturography (sensory orgnization test)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Skin Aging
Pilot Study to Evaluate the Safety and the Efficacy of the Matrix and Cells Obtained by the AmeaCell® Device and Intended for the Filling of Wrinkles on the Face.
The purpose of this study is to evaluate the filling using the Matrix and Cells, obtained by the Ameacell® device from autologous adipose tissue and intended for the filling of wrinkles on the face.
- Trial name
- SKINMAT (NCT03529292)
- Testing
- AmeaCell
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Symbioken
Sarcopenia, Frailty
Muscle Biopsies in Healthy Volunteers
Background: In individuals as they age, changes in muscle tissue can significantly affect their muscle strength and exercise endurance.
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT01431677
- Testing
- Muscle Biopsy
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Aging
Can Synbiotic Use Effect Gut Bacteria and the Immune Response in Older People
The objectives of this study are to use a nutritional change in the diet to improve gut health in older people. Ageing can result in major changes in the composition and activities of the bacteria in your gut, leading to a higher…
- Trial name
- NCT01226212
- Testing
- Synbiotic (Synergy 1/B. longum)
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Dundee