Clinical trials: Adverse Childhood Experience
Adverse Childhood Experiences
Childhood Trauma, Exercise, and Cognition
This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood.
- Trial name
- CTEC (NCT05972265)
- Testing
- Moderate Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Adverse Childhood Experiences
ACEs Referral From PED
Adverse childhood experiences (ACEs) are traumatic exposures that can cause many negative health impacts across life. ACEs are common in patients who seek out care in pediatric emergency departments (PEDs); this is an opportunity…
- Trial name
- NCT06574633
- Testing
- In-person therapy, Telehealth therapy
- Where
- 4 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Emory University
Chronic Pain, Trauma
Brief Intervention for Chronic Pain and History of Stressful Experiences
The goal of this study is to understand whether a brief, three session program can be helpful in reducing symptoms related to both chronic pain and stressful experiences/trauma.
- Conditions
- Chronic Pain, Trauma, Adverse Childhood Experiences
- Trial name
- NCT06983327
- Testing
- Trauma Focused Emotional Awareness and Expression Therapy (EAET)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Adolescent Behavior, Stress Reduction
CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention
Using an adapted stress-reduction intervention called the CEDARS, the investigators will pilot the intervention in adolescents (N=40) to determine the feasibility and acceptability of CEDARS implementation and to investigate…
- Conditions
- Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
- Trial name
- CEDARS (NCT04958694)
- Testing
- CEDARS
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Child Development
Caregiver Adverse Childhood Experiences (ACEs) in Pediatric Primary Care
This longitudinal study will evaluate if increased caregiver awareness of their own ACEs through provider-led discussions will lead to improved child health via fewer emergency department, urgent care visits and missed primary…
- Trial name
- NCT05013138
- Testing
- Training for ACEs and study procedures, Training on study procedures
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Emory University
Adverse Childhood Experiences
The FACE Self-help App for Fostering Resilience
The FACE self-help app is an online intervention for young adults with Adverse Childhood Experiences (ACEs). It was developed based on well-established cognitive-behavioural therapy principles.
- Trial name
- NCT05824182
- Testing
- FACE self-help App
- Where
- Switzerland
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Jeannette Brodbeck
Overweight, Obesity
Relationship of Adverse Childhood Experiences to Overweight and Obesity
The purpose of this study is to determine if there is an association between a variety of adverse childhood experiences and overweight and obesity.
- Trial name
- NCT00632346
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Drug Addiction
Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old.
- Trial name
- NCT05958641
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Adverse Childhood Experiences and Adolescent Mental Health
Self-Compassion Based Psychoeducation Program for Adolescents With Adverse Childhood Experiences
This randomized controlled experimental study examined the effects of a brief self-compassion intervention program (BSCIP) on mental health outcomes among adolescents reporting four or more adverse childhood experiences (ACEs).
- Trial name
- BSCIP-ACE (NCT07875439)
- Testing
- Brief Self-Compassion Intervention Program (BSCIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ahmet Alkal
Chronic Pain, Central Sensitisation
Childhood Adversity, Inflammatory Reactivity and Persistent Pain
The goal of this observational study is to investigate how adverse experiences during childhood are linked to people experiencing persistent pain and fatigue in adulthood. The questions the investigators aim to answer are: 1.
- Conditions
- Chronic Pain, Central Sensitisation, Immune Response, Adverse Childhood Experiences
- Trial name
- CAIR (NCT06127693)
- Testing
- Tetravalent Influenza Vaccine, High-frequency electrical stimulation
- Where
- South Africa
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Health Services, Mental Health
Telephone-Based Care Coordination for Services Addressing Childhood Adversity
The goal of this study is to learn how telephone-based screening and care coordination impacts children experiencing adverse childhood events (ACEs). The main questions are: 1.
- Conditions
- Health Services, Mental Health, Well-being
- Trial name
- CARE (NCT07686614)
- Testing
- Telephone-based Screening and Care Coordination
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Paul Chung
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Lower Urinary Tract Symptoms (LUTS), Transition Care
Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent Years
With this study, we would like to interview 16-25-year-olds who have experienced urinary problems since childhood and who are still experiencing symptoms in young adulthood.
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Transition Care, Enuresis Nocturnal, Adverse Childhood Experiences
- Trial name
- STREAMWAY (NCT07339865)
- Testing
- Semi-structured in-depth interviews with standardized validated questionnaires, Completion of a urological time-line
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Adverse Childhood Experiences
ACE, Resilience, and Substance Use Disorder: Maternal and Baby Outcomes in the First Year of Life
The purpose of this study is to understand maternal factors, including ACE and 7Cs Tool scores, and how they contribute to the health of mothers and their infant.
- Trial name
- NCT05731557
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Healthy
Oxytocin Administration and Emotion Recognition Abilities in Adults Reporting Adverse Childhood Experiences
This study evaluates whether intranasal administration of a single dose of oxytocin improves the ability to recognize emotional states.
- Trial name
- NCT03335085
- Testing
- Oxytocin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Chronic Pain, Adverse Childhood Experiences
Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.
In the present research study, aiming to explore the links between several psychological factors and chronic pain, the research seeks to develop an inclusive framework to investigate the role of adverse childhood experiences…
- Conditions
- Chronic Pain, Adverse Childhood Experiences, Attachment Styles, Chronic Stress
- Trial name
- NCT06077097
- Testing
- Biological samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University of Lorraine
Stress, Childhood Obesity
Healing Experiences of Adversity Among Latinos (HEALthy4You)
Healing Experiences of Adversity Among Latinos (HEALthy4You) is a project funded by the California Initiative for the Advancement of Precision Medicine ("Advancing a Precision Population Health Approach to ACEs to Reduce Health…
- Trial name
- NCT05676281
- Testing
- Healthy Together (Control), Healthy Together + Promotora Support, Healthy Together + Parenting Training
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Menopause, Healthy Adult
Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health
The purpose of this study is to learn more about how estradiol patch treatment affects brain processes, health, and wellbeing.
- Conditions
- Menopause, Healthy Adult, Brain, Postmenopausal
- Trial name
- CEREBRA (NCT07831499)
- Testing
- Cyclic Estradiol, Continuous Estradiol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland