Clinical trials: Adult Intensive Care Patients
Critically Ill Patients, Mechanical Ventilation
Tight Glycemic Control by eMPC Algorithm in Medical ICU Patients.
This is an open mono-centre randomised controlled trial performed at the Medical University Graz including a treatment visit (V1).
- Conditions
- Critically Ill Patients, Mechanical Ventilation, Hyperglycemia
- Trial name
- NCT00460252
- Testing
- insulin titration applying a computer algorithm
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Tracheostomy Patients, Tracheostomy Decannulation
Tracheostomy Practice in Adult Intensive Care Units
ON TRACH is an international, multicentre, observational study with the aim of characterising the timing and practice of tracheostomy insertion, management, weaning and longer-term outcomes of these patients, in intensive care…
- Conditions
- Tracheostomy Patients, Tracheostomy Decannulation, Intensive Care (ICU)
- Trial name
- ON TRACH (NCT07769021)
- Where
- 13 sites in United States, Brazil and 6 more
- Volunteers
- 2,500 people
- Sponsor
- Royal College of Surgeons, Ireland
Statistical Analysis of Traumatic Brain Injury Victims
Morbidity and Mortality in Solo Adult Traumatic Brain Injury Patients in Minia University Hospital
Tracking post-traumatic brain injury sequale
- Trial name
- NCT05075239
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Minia University
Artificial Intelligence, Central Venous Catheter Associated Bloodstream Infection
Artificial Intelligence With Determination of Central Venous Catheter Line Associated Infection Risk
The goal of this methodological, retrospective and prospective study is to; it is a tool to develop a risk estimator tool to detect risk gaps in individuals using artificial intelligence technology that is dangerous for those…
- Trial name
- NCT05914571
- Volunteers
- 2,000 people
- Sponsor
- Saglik Bilimleri Universitesi
Critically Ill
Impact of SPN on Infection Rate, Duration of Mechanical Ventilation & Rehabilitation in ICU Patients
Rationale: Enteral nutrition (EN) in the intensive care (ICU) patients is recommended as a standard of care. However, EN alone is often associated with insufficient energy intakes and increased complication rates.
- Trial name
- NCT00802503
- Testing
- SPN
- Where
- 2 sites in Switzerland
- Volunteers
- 305 people
- Sponsor
- University Hospital, Geneva
Bronchial Aspiration
Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay
Patients of age >18 yo, admitted to the ICU through the surgery department from 2AUG2021 to 1AUG2022 will be divided into three groups: 1.
- Trial name
- NCT05284084
- Testing
- Bed Head elevation, H2 blockers and mouth wash, Data collection for comparison
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Marshall University
Bacterial Infections
PROcalcitonin Reduce Antibiotic Treatments in Acute-Ill Patients (PRORATA)
The study is a prospective, randomized, controlled intervention trial conducted in 9 centers, comparing a conventional strategy versus a PCT-guided strategy to start or to discontinue antibiotics, in patients with suspected…
- Trial name
- PRORATA (NCT00472667)
- Testing
- Procalcitonin guided strategy
- Where
- France
- Volunteers
- 630 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Intensive Care (ICU) Myopathy, Functional Independence
Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients
Several complications and comorbidities are frequently found in patients admitted to an Intensive Care Unit (ICU), including acquired ICU muscle weakness and physical and cognitive limitations.
- Trial name
- NCT03619915
- Testing
- Spirometry, Functional Independence Measure
- Volunteers
- 197 people
- Sponsor
- Universidade Estadual do Oeste do Paraná
Sleep Disturbance, Delirium
Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients
Sleep disturbance is very common among critically ill patients in the intensive care unit (ICU), particularly in older adults after surgery.
- Conditions
- Sleep Disturbance, Delirium, Critical Illness
- Trial name
- NCT07407400
- Testing
- Lemborexant
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Mucosal Wound, Mucosal Erosion
The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries
Intensive care units (ICUs) are care centers equipped with a wide range of technological tools and devices used to provide the highest level of care to individuals whose lives are at risk, requiring a multidisciplinary team…
- Conditions
- Mucosal Wound, Mucosal Erosion, Mucosal Irritation, Endotracheal Intubation Fixation
- Trial name
- PreventionMMPI (NCT07390162)
- Testing
- Changes in the frequency of endotracheal tube repositioning
- Volunteers
- 230 people
- Sponsor
- Hacettepe University
Effect of Age on Mortality, ICU Mortality
Impact of Age on Mortality in Critically Ill Adult Patients in Nepal- a Single Center Retrospective Study of 5 Years.
Rationale: Age is often considered a strong factor that determines the outcomes in critically ill patients. In a resource limited low middle income country (LMIC) like Nepal, the age factor is often considered when making…
- Conditions
- Effect of Age on Mortality, ICU Mortality, Age
- Trial name
- NCT06888206
- Where
- Nepal
- Volunteers
- 8,189 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
All Adult Patients Admitted to theHMPIT ICU for Management of Head Trauma
Quality of Life in Traumatic Brain Injury Patients
The aim of this study is to describe the quality of life of CT patients in our study, at least 6 months after the occurrence of the trauma. This assessment is related to the patient's degree of sequelae, using the GOSE scale.
- Trial name
- NCT05993312
- Testing
- quality of life
- Where
- 2 sites in Tunisia
- Volunteers
- 100 people
- Sponsor
- General Administration of Military Health, Tunisia
Critical Illness, Critically Ill Patients
Physiological Changes in Adult Intensive Care Patients Following Contact With Their Primary Caregiver
Patients admitted to intensive care units are exposed to multiple environmental and clinical factors that may affect their physiological responses.
- Trial name
- CARE-ICU (NCT07761364)
- Testing
- Standardized therapeutic physical contact
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30
Interest of Hypnosis When Setting up Non-invasive Ventilation in a Conscious Patient With COPD and/or Obesity With a BMI Greater Than 30, Suffering Fromacute Respiratory Distress in Adult Intensive Care
Discomfort during respiratory decompensation of a patient with chronic obstructive pulmonary disease (COPD) and/or obesity with a BMI greater than 30, in intensive care and the establishment of non-invasive ventilation (NIV) is…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30, Acute Respiratory Distress in Adult Intensive Care
- Trial name
- HYVIR (NCT04220463)
- Testing
- Hypnosis + NIV, NIV
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Frailty, Septic Shock
Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted to Intensive Care for Septic Shock.
The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined as having a CFS score between [6-7] as defined by Bagshaw et al (14)…
- Trial name
- Woodstock (NCT05928767)
- Where
- 5 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Lens
Acute Kidney Injury
Renal Angina Index for Predicting Acute Kidney Injury in Adult ICU Patients
Acute kidney injury (AKI) is a frequent complication of critical illness and is associated with increased morbidity and mortality.
- Trial name
- NCT07863505
- Testing
- Renal Angina Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Izmir Katip Celebi University
Hyperglycemia
Feasibility Study to Evaluate Safety and Device Performance of the Hospital Glucose Management System (HGMS)
The purpose of this study is to assess safety and device performance of the Medtronic Hospital Glucose Management System (HGMS) for up to 72-hours.
- Trial name
- MAHI (NCT01763567)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Medtronic MiniMed, Inc.
Acute Brain Injury
Frontal Bone Window in ICUF (FBW-ICU)
Transcranial doppler (TCD) is an established tool for monitoring flows in intracranial cerebral arteries. Its use is recommanded in the last guidelines on traumatic brain injury.
- Trial name
- FBW-ICU (NCT02832895)
- Testing
- Transcranial doppler examination
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Nutritional and Metabolic Diseases
Smart Phone Application for Enteral Nutrition
Internal medicine resident physicians were provided an ipod with the EN application to assist them in choosing EN formulas for patients during their ICU rotation.
- Trial name
- NCT03419299
- Testing
- Tube Feeding Application
- Volunteers
- 376 people
- Sponsor
- University of Oklahoma