Clinical trials: Adolescent Development
Autism Spectrum Disorder, Obesity
Semaglutide in Youth With Autism Spectrum Disorder
This study is a 6-month, two-arm, RCT which will evaluate the effectiveness and safety of semaglutide in adolescents aged 12-18 years with autism spectrum disorder (ASD) and obesity.
- Trial name
- GLP1 (NCT07770152)
- Testing
- Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorders
Improving Participation of Autistic Children and Adolescents in the Habilitation Process
This project aims to explore the impact of a survey-based and a meeting-based needs assessment models on 7 to 17 year old autistic children's participation in the needs assessment process at the initial reception when enrolled at…
- Trial name
- IMPAC (NCT06381856)
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Örebro County
Developmental Coordination Disorder
Influence of Sensory Stimulation on Sensory Parameters and Motor Function in Children With Developmental Coordination Disorder
The goal of this clinical trial is to evaluate whether intensive sensory stimulation therapy can improve upper limb motor skills and sensory function in children aged 12-16 years with severe symptoms of Developmental Coordination…
- Trial name
- NCT06959329
- Testing
- Active and passive physical therapy without intensified sensory stimulation, Active and passive physical therapy with intensified sensory stimulation
- Where
- 2 sites in Latvia, Poland
- Volunteers
- 80 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Adolescent Behavior, HIV
Adolescent Transition To Adult Care for HIV-infected Adolescents in Kenya
This study evaluates an adolescent transition package (ATP) to support HIV infected adolescents transitioning form pediatric/adolescent care to adult care.
- Conditions
- Adolescent Behavior, HIV, Transition, Adolescent Development
- Trial name
- ATTACH (NCT03574129)
- Testing
- Adolescent Transition Package
- Where
- Kenya
- Volunteers
- 1,095 people
- Sponsor
- University of Washington
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
HIV/AIDS, HIV Infections
Tushirikiane HIV-self Testing Intervention With Urban Refugee Youth in Kampala, Uganda
HIV is the leading cause of death for adolescents and young people (AYP) in sub-Saharan Africa (SSA). Uganda hosts 1.3 million refugees/displaced persons, and more than 80,000 live in Kampala, most in slums, yet little is known…
- Conditions
- HIV/AIDS, HIV Infections, Knowledge, Attitudes, Practice
- Trial name
- Tushirikiane (NCT04504097)
- Testing
- m-Health, HIV self-testing
- Where
- Canada
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Adolescent Development
Inspiratory and Expiratory Muscle Training in Adolescent Volleyball Players
This study will investigate the effects of inspiratory and expiratory muscle training on respiratory muscle strength, pulmonary function, and performance status in adolescent athletes
- Trial name
- NCT06759779
- Testing
- inspiratory muscle training, expiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Gazi University
Serious Emotional Disturbance
Family Health and Development Project
The Family Health and Development Project (FHDP) is a randomized controlled trial to evaluate the effectiveness of the Intensive In-home Child and Adolescent Psychiatric Service (IICAPS) intervention, targeting emotionally…
- Trial name
- FHDP (NCT01567969)
- Testing
- Intensive In-home Child and Adolescent Psychiatric Service, Home-based Child Treatment Coordination
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Yale University
Behavior, Child, Child Development
Vulnerability/Resilience Factors Influencing the Developmental Trajectories and Adaptive Methods of Children and Adolescents in Child Welfare System.
Assess the prevalence of medico-psychological characteristics at the time of placement (M0), their appearance / disappearance and during the two years following placement (M12 and M24) by age group in children / adolescents in…
- Conditions
- Behavior, Child, Child Development, Child Development Disorder, Adolescent Development
- Trial name
- EvolASE-PEA (NCT05525962)
- Testing
- questionnaries, scales, cognitive tests
- Where
- 5 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Autism, Autism Spectrum Disorder High-Functioning
PRT for Adolescents With High Functioning Autism
The purpose of this study is to identify improvement in behavioral and social function and changes in the brain following Pivotal Response Treatment (PRT) for Adolescents in highly verbal adolescents with autism spectrum disorder…
- Conditions
- Autism, Autism Spectrum Disorder High-Functioning, Developmental Disability, Child Development
- Trial name
- NCT05987761
- Testing
- PRT for Adolescents
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Stanford University
Preterm Birth
Adolescents Born Preterm; Nurtured Beginnings
This research study is a long-term follow-up to an earlier study of developmental care. For that study, high risk preterm newborns were randomly assigned to a standard care group, which received the standard care offered in the…
- Trial name
- NCT00310869
- Testing
- Individualized Developmental Care in the NICU
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Intellectual Disability, Adolescent Development
Prevention Among Young People With Intellectual Disability
This study aims to evaluate an intervention using the Toolkit "Children - what does it involve?" and the "Real-Care-Baby" (RCB) simulator among students with intellectual disability (ID), using a cluster randomized trial design…
- Conditions
- Intellectual Disability, Adolescent Development, Young Adult
- Trial name
- NCT03348124
- Testing
- "Children - what does it involve?"
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Uppsala University
Depression, Anxiety
Black Youth M.A.T.T.E.R: Positive Youth Development Group Intervention
One in three Black boys born today in the United States will be incarcerated at some point in their lifetime, compared to one in 17 White boys. Black males are more likely to be arrested, convicted, and given unfair sentences.
- Trial name
- BYM (NCT03804242)
- Testing
- Black Youth M.A.T.T.E.R.: Molding Young Advocates While Transforming the School to Prison Pipeline Through Psychological Services Education and Resilience
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Autism
Valproate Response in Aggressive Autistic Adolescents
This study will examine the effect of valproate, a medication used to treat seizures and bipolar disorder, on aggressive behavior in children and adolescents with autism.
- Trial name
- NCT00065884
- Testing
- Valproate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Neuroimaging of Escitalopram in Autism Spectrum Disorder
The goal of this clinical trial is to evaluate the acute effects of escitalopram (Lexapro®) on select brain networks during task-based functional magnetic resonance imaging (fMRI) in adolescent individuals with autism spectrum…
- Trial name
- NCT06826326
- Testing
- Escitalopram 10mg
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kathryn Unruh
Health Literacy
Psychoeducational Intervention to Promote Adolescents' Mental Health Literacy in a School Context
Mental Health Literacy was defined as knowledge and beliefs about mental disorders that aid in its recognition, management or prevention.
- Trial name
- NCT03872817
- Testing
- Intervention ProLiSMentAl
- Volunteers
- 38 people
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Marfan Syndrome
Marfan Syndrome Moderate Exercise Pilot
Marfan syndrome (MFS) affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection.
- Trial name
- NCT04641325
- Testing
- Exercise Intervention Group
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder
Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Open-label Study to Investigate the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents.
- Conditions
- Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder, Autism Spectrum Disorder, Smith-Magenis Syndrome
- Trial name
- NCT02776215
- Testing
- tasimelteon
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanda Pharmaceuticals
Child Development
Randomized Trial of the Effects of Musical Training on Child Development in the Venezuela Orchestra Program (El Sistema)
This study evaluates Venezuela's National System of Child and Youth Orchestras, better known as "El Sistema".
- Trial name
- NCT02369315
- Testing
- Treatment (Invited entry 2012), Control (Invited entry 2013)
- Volunteers
- 2,914 people
- Sponsor
- Inter-American Development Bank