Clinical trials: Adjustment Disorders
Atrial Fibrillation, Persistent
Rate Control Self-adjustment in Patients With Permanent or Persistent Atrial Fibrillation Using Device Home Monitoring
Patients with permanent or persistent atrial fibrillation require rate control medication to prevent excessive tachycardia. Since too much medication leads to a lower than expected heart rate (low output and symptoms) and too…
- Trial name
- NCT05066971
- Testing
- Self-adjustment of medication
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Female Infertility
Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles
Hormonal monitoring impact on overall pregnancy rate in frozen embryo transfer (FET)cycles and hence progesterone supplement adjustments remain debatable in current literature.
- Trial name
- NCT05189145
- Testing
- estradiol valerate, Hormonal monitoring progesterone, estradiol, luteinizing hormone, transvaginal ultrasound examination
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Alexandria University
Mastocytosis, Indolent Systemic
Evaluation of the DALY on a Cohort of Patients With Indolent Systemic Mastocytosis
Mastocytosis is a group of pathologies characterized by the accumulation and/or clonal proliferation of abnormal mast cells in various organs.
- Trial name
- DALY-MAST (NCT05923372)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Toulouse
Congestive Heart Failure (CHF)
Group Psychotherapy Among Congestive Heart Failure Patients
This study will examine the efficacy of group therapy utilizing the Existential Approach in heart failure patients when compared to a control group of patients who are waiting for the same group treatment.
- Trial name
- NCT01414439
- Testing
- Existential Group Therapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Respiratory Failure
Comparative Effects on Diaphragmatic Electrical Activity and Respiratory Pattern of Various Levels of Assistance
Exploration of the effects on diaphragmatic electrical activity (EMG) and on respiratory pattern of various level of assistance delivered by the ventilator in intubated spontaneously breathing patients in pressure support (PS)…
- Trial name
- NCT01248845
- Testing
- Titration of various level of assistance
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Prof. Philippe Jolliet
Precursor Lymphoid Neoplasms
Personalized Therapy of Precursor Lymphoid Neoplasms
The primary goal of this study by The Polish Adult Leukemia Group (PALG) is to verify if individual therapeutic approach taking into account biological and phenotypic differences as well as response at the level of minimal…
- Trial name
- NCT01665001
- Testing
- Treatment strategy: induction, consolidation, HSCT, maintenance
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice
Carcinoma, Non-Small-Cell Lung
Central European Society for Anticancer Research (CESAR) Study of Paclitaxel Therapeutic Drug Monitoring
This study will be performed on grade IIIb and grade IV Non Small Cell Lung Cancer (NSCLC) chemotherapy naive patients with good performance status.
- Trial name
- CEPAC-TDM (NCT01326767)
- Testing
- Paclitaxel dosing according to SmPC, Individualized pharmacokinetically driven paclitaxel dosing
- Where
- 11 sites in Germany, Switzerland
- Volunteers
- 366 people
- Sponsor
- Central European Society for Anticancer Drug Research
Ostomy - Ileostomy or Colostomy, Canser
The Effect of Ostomy Care Education Applied With the Teach-Back Method to Ostomy-Opened Individuals on Self-Care Power, Ostomy Adjustment, and Anxiety
The aim of this study is to examine the effect of ostomy care education-delivered to patients who have undergone ostomy surgery using the Teach-back method on patients' self-care ability, ostomy compliance, and anxiety levels.
- Conditions
- Ostomy - Ileostomy or Colostomy, Canser, Ileus, Intestinal Cancer
- Trial name
- NCT07788079
- Testing
- TEACH BACK METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi
Hypertension, Pulmonary
Efficacy and Safety of Ambrisentan in Children 8-18yrs
A 6-month (24-week), randomized, open label evaluation of the safety, tolerability, and efficacy of a high and low dose ambrisentan (adjusted for body weight) treatment group in subjects aged 8 years up to 18 years with pulmonary…
- Trial name
- NCT01332331
- Testing
- Ambrisentan - low dose, Ambrisentan - high dose
- Where
- 24 sites in United States, Argentina and 7 more
- Volunteers
- 41 people
- Sponsor
- GlaxoSmithKline
Gambling
Effectiveness of Exergames on Cognitive, Social Functionamong Chronic Schizophrenia
An experimental study with random assignment will be adopted. The participants from 2 hospitals will be assigned to two groups: experimental group (n=77), and control group (n=77).
- Trial name
- exergames (NCT05933356)
- Testing
- playing exergames, scheduled activities
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Morbid Obesity
Outcomes of Gastric Band Fills as Found With a Patient Self-reported Questionnaire: The Vomiting, Eating, and Weight Loss (VEW) Questionnaire
1. Background / Scientific Rationale The VEW (Vomiting, Eating, and Weight Loss) Questionnaire has been developed as a method for the assessment of post bariatric surgery patients, as well as a research tool into the eating…
- Trial name
- NCT01105156
- Testing
- VEW Questionnaire
- Where
- Australia
- Volunteers
- 361 people
- Sponsor
- North Eastern Weight Loss Surgery
Lymphoma, T-Cell, Lymphoma, Extranodal NK-T-Cell
Campath-1H and EPOCH to Treat Non-Hodgkin's T- and NK-Cell Lymphomas
Background: The paradigm of combining therapeutic agents with non-overlapping toxicities for the treatment of malignancy produces clinical remissions and cures in a number of tumor types.
- Trial name
- NCT00069238
- Testing
- Alemtuzumab (Campath), EPOCH
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Cancer Institute (NCI)
Prodromal Schizophrenia
Neurofeedback Training for High Risk Psychosis
Young people who are at great risk for developing psychosis have cognitive deficits which are strongly related to functioning in the community.
- Trial name
- NCT03447548
- Testing
- Neurofeedback processing speed training, Active control
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Hartford Hospital
Thrombosis Prophylaxis (Risk of Thrombosis Due to Central Venous Line (CVL)
Study of AVE5026 at Weight-adjusted Doses in Children With a Central Venous Line
Primary Objective: To assess the pharmacokinetic (PK) and pharmacodynamic (PD) parameters of Semuloparin [AVE5026] (assessed from the anti-Xa activity of Semuloparin) in children in order to determine the dose to be assessed in a…
- Trial name
- NCT01567904
- Testing
- Semuloparin sodium
- Where
- Hungary
- Volunteers
- 2 people
- Sponsor
- Sanofi
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Post-Concussion Syndrome
Post-concussion Syndrome and Chiropractic
This proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome.
- Trial name
- PCS (NCT06151184)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Life University
HIV Infections
Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug Resistance
The purpose of this study is to see if adjusting the dose of lopinavir/ritonavir (LPV/r) has a better effect on lowering HIV viral load (the amount of HIV in the blood) compared to taking the standard FDA-approved LPV/r dose.
- Trial name
- NCT00046033
- Testing
- Lopinavir/ritonavir, Ritonavir, Saquinavir
- Where
- 6 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ferula Deportiva
Effects of a Training Oral Device (Custom Splint) Adjusted Using Electromyography for the Balance Between the Masseter and Temporal Muscle in Elite Military Paratroopers.
The aim of this prospective, longitudinal observational study is to evaluate the influence of the use of sports splints on the muscular activity of the stomatognathic system and cervical mobility in adult sport parachutists.
- Trial name
- NCT07523984
- Testing
- Effects of a Training Oral Device (Custom Splint) Adjusted Using Electromyography
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University