Clinical trials: Adjustment
Bronchopulmonary Dysplasia
Neurally Adjusted Ventilatory Assist vs Proportional Assist Ventilation
This study aims to assess whether neurally adjusted ventilatory assist or proportional assist ventilation is more effective in infants born prematurely with evolving or established bronchopulmonary dysplasia
- Trial name
- NCT02967549
- Testing
- NAVA, PAV
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
Asses Immunosuppression Modulation on Renal Recovery Post LT
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant
This is a study to help understand how well new combinations of immunosuppressive medications (medications that weaken your immune system to prevent your body from rejecting the transplanted liver) work compared to standard…
- Trial name
- NCT04104438
- Testing
- Basiliximab 20 MG
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Fady M Kaldas, M.D., F.A.C.S.
Tracheostomized Patients, Depression
The Effect of Mobile Application-Based Education Given to Patients With Tracheostomy on Depression, Social Adaptation and Quality of Recovery
The Effect of Mobile Application-Based Education Given to Patients with Tracheostomy on Depression, Social Adaptation and Quality of Recovery
- Conditions
- Tracheostomized Patients, Depression, Social Adaptation, Quality of Recovery
- Trial name
- NCT07337668
- Testing
- Mobile application-based education, Standart Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Patients Treated With Voriconazole
Preliminary Experience of Routine Voriconazole Therapeutic Drug Monitoring (TDM) in a Tertiary Care Centre
The first goal of this study is to map all the subtherapeutic, therapeutic and supratherapeutic voriconazole plasma levels in the University Hospitals Leuven.
- Trial name
- NCT01418833
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Human Immunodeficiency Virus
Cognitive-Based Compassion Training (CBCT) for People Living With HIV (PLHIV)
The purpose of the study is to examine the effects of cognitive-based compassion training (CBCT), a meditative practice based on Buddhist teachings, on long term emotional well-being and immune system improvement with people…
- Trial name
- NCT02395289
- Testing
- Cognitive-Based Compassion Training (CBCT), Health discussion
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Emory University
Stroke
Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes
This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity…
- Trial name
- NCT06640101
- Testing
- IMT-stable group (sitting on a stable surface), IMT-unstable group (sitting on an unstable surface), Conventional treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Hong Kong Metropolitan University
Thoracic Surgery, Tidal Volume
Tidal Volume Adjustment According to Forced Vital Capacity Versus Predicted Body Weight in Thoracic Surgery Patients
The goal of this observational study is to learn about the intraoperative and postoperative pulmonary effects of tidal volume adjustment according to force vital capacity in thoracic surgery patients.
- Conditions
- Thoracic Surgery, Tidal Volume, Forced Vital Capacity, Predicted Body Weight
- Trial name
- NCT06608602
- Testing
- tidal volume adjustment during surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Lymphoma
Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate tumor cells and either kill them or deliver tumor-killing…
- Trial name
- NCT00032019
- Testing
- filgrastim, rituximab, cyclophosphamide
- Where
- 81 sites in United States, Puerto Rico
- Volunteers
- 78 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Adjustment Impairment, Accident
SelFIT: Internet-based Treatment for Adjustment Problems After an Accident
In this study, people who suffer from adjustment problems after having experienced an accident will be randomized to one of two study groups.
- Conditions
- Adjustment Impairment, Accident, Adjustment Disorders, Mental Disorder
- Trial name
- SelFIT (NCT03785912)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University of Bern
Diabetes Mellitus Type 2, Hospitalization
Effect of the Use of Continuous Glucose Monitoring Versus Standard Glycemic Control in Hospitalized Patients with Type 2 Diabetes.
Type 2 diabetes (T2D) is a common pathology in hospitalized patients and is associated with multiple comorbidities. Moreover, it is widely known that glycemic excursions increase hospital stay, infections, morbidity and…
- Trial name
- NCT06607224
- Testing
- Experimental (Decision making guided by CGM)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Gout, Inflammatory Rheumatism
Treat-to-target by Email During Urate-lowering Therapy in Gout
Gout is secondary to urate crystal deposition after chronic elevation of serum urate level (SUL). Long-term lowering SUL below 360 µmol/L allows dissolution of deposited crystals and disease cure.
- Conditions
- Gout, Inflammatory Rheumatism, Hyperuricemia, Posology Adjustment
- Trial name
- GOUTEmail (NCT04733079)
- Testing
- Cleanweb electronic messaging ePro, Usual follow-up
- Where
- 2 sites in France
- Volunteers
- 204 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intracranial Tumor
Treatment Effects Inclusive Cognitive Impact and Possibilities to Individually Adjusted Treatment in Patients With Intracranial Tumors With Clinical, Neuropsychological and Imaging Parameters
The main purposes with this trial is to investigate the potential of MRI with diffusion and blood volume, flow in brain to diagnose and to measure treatment effects in patients with intracranial tumors, especially gliomas and…
- Trial name
- NCT01674582
- Testing
- MRI, neuropsychological evaluation, blood sampling
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University Hospital
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Trial of the Youth Readiness Intervention
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial and functioning outcomes in youth.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Stress, Psychological
- Trial name
- YRI (NCT01684488)
- Testing
- YRI, EducAid educational programming
- Where
- Sierra Leone
- Volunteers
- 443 people
- Sponsor
- Boston College
Atrial Fibrillation
Phase 2 Study of the Safety, Tolerability and Pilot Efficacy of Oral Factor Xa Inhibitor Betrixaban Compared to Warfarin
Prevention of stroke in patients with atrial fibrillation (AF). Hypothesis: In patients with non-valvular AF, orally administered betrixaban will provide similar or better efficacy and safety than warfarin and it will offer the…
- Trial name
- EXPLORE-Xa (NCT00742859)
- Testing
- betrixaban, Warfarin
- Where
- 21 sites in United States, Canada
- Volunteers
- 508 people
- Sponsor
- Portola Pharmaceuticals
Endometrial Cancer
Endometrial Cancer International Database
This project aims to determining prognostic factors and individualizing management decision per patient characteristics and endometrial cancer features.
- Trial name
- ECID (NCT04787159)
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
Heart Failure, Heart Failure - NYHA II - IV
Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure
The goal of this clinical trial is to learn if increasing the dose of diuretics to achieve a higher urine sodium target produces better clinical results when treating patients hospitalized with acute heart failure when compared…
- Conditions
- Heart Failure, Heart Failure - NYHA II - IV, Heart Failure Acute, Acute Heart Failure (AHF)
- Trial name
- US-DASH (NCT07263035)
- Testing
- Furosemide intravenous solution
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Lakeland Regional Health Systems, Inc.
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela
Schizophrenia
β-Cell Function in Schizophrenic Subjects on Atypical Antipsychotic drugS
The purpose of this study is to determine whether atypical antipsychotic drugs (commonly prescribed for treating schizophrenia) induce changes in anthropometry and metabolism, including alteration in insulin sensitivity and/or…
- Trial name
- SANAT (NCT00528359)
- Testing
- quetiapine or olanzapine or risperidone or aripiprazole
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cognitive Impairment, Depression, Anxiety
intErnet-based iNterventions FOR Cardiac arrEst suRvivors
This randomized clinical trial will test whether an internet-based lifestyle intervention administered through a web app can foster Health Related Quality of Life in patients who survived an out-of-hospital cardiac arrest and…
- Conditions
- Cognitive Impairment, Depression, Anxiety, Cardiac Arrest, Quality of Life
- Trial name
- ENFORCER (NCT06395558)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Italy
- Volunteers
- 106 people
- Sponsor
- Azienda Usl di Bologna
Adjustment Disorders
Internet-based Self-help for Negative Life Events
The purpose of the study is to investigate the efficacy of an internet-based self-help intervention for dealing with stressful life events.
- Trial name
- ZIEL (NCT03379155)
- Testing
- Internet-based self-help program
- Where
- 2 sites in Switzerland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Bern