Clinical trials: Adiposity
Postoperative Wound Healing
Role of Subcutaneous Negative Pressure Suction Drain Placed for Ten Days on Wound Healing in Obese Patients Undergoing Midline Laparotomies
The aim of the study is to evaluate the role of subcutaneous negative pressure drain placed for 10 days on wound healing in female obese patients undergoing midline exploratory laparotomies for ovarian cancer.
- Trial name
- NCT02832076
- Testing
- Subcutaneous negative suction drain for 10 days, No subcutaneous drain
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams Maternity Hospital
Hypercoagulability, Obesity
Effect of Phototherapy With Exercise on Coagulation in Elderly
It is an interventional study in which 60 obese elderly patients (30 male \& 30 female) estimated to enroll according to random allocation and divided into two groups.
- Trial name
- NCT04503317
- Testing
- active acupuncture low level laser in addition to nasal laser irradiation, treadmill exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Obesity, Overweight
Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial Cancer
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of mazdutide combined with a levonorgestrel-releasing intrauterine…
- Conditions
- Obesity, Overweight, Atypical Endometrial Hyperplasia, Endometrial Carcinoma Stage I
- Trial name
- MELIA (NCT07781150)
- Testing
- Mazdutide(Dual GLP-1R/GCGR Agonist), Levonorgestrel-releasing intrauterine system
- Where
- 6 sites in China
- Volunteers
- 128 people
- Sponsor
- Tongji Hospital
Obesity and Overweight, Sleep Disorder
Overweight and Obesity in Adolescents - Sleep Behavioral Intervention
Sleep plays a crucial role in energy balance, alongside diet and physical activity. Research has linked poor sleep quality and short sleep duration to obesity and cardiometabolic risk, such as insulin resistance and hypertension.
- Trial name
- SLEEP-OB (NCT07255274)
- Testing
- Sleep Behavioral Intervention, Standard Obesity Treatment
- Where
- 2 sites in Portugal
- Volunteers
- 126 people
- Sponsor
- University of Beira Interior
Obesity, Morbid
Modeling the Neurological Basis and Characterizing the Neurological Phenotype of Obesity Using Human Neural Stem Cells
This study aims to characterize the neurological basis of obesity and response to surgical and medical treatment by inducing adult pluripotent stem cells into neuronal cells from subjects that have demonstrated extreme response…
- Trial name
- NCT03263390
- Testing
- Bariatric Surgery, Anti Obesity Drugs
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Diego
Obesity
Acupuncture for Obesity on Serum Metabolic Parameters
This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.
- Trial name
- NCT02066090
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Obesity, Adolescent Behavior
Obesity in Schoolchildren of Basic Education - Phase III
The study aims to evaluate the possible effects of an exercise program, nutritional and psychological, postural orientation and guidance of oral health on body composition, physical activity levels and lifestyle, physical fitness…
- Trial name
- NCT02769897
- Testing
- Physical exercise
- Volunteers
- 50 people
- Sponsor
- University of Santa Cruz do Sul
Postoperative Nausea and Vomiting
Compare Between Two Doses of Palonosetron on the Prevention of Postoperative Nausea and Vomiting in Obese Patients
BACKGROUND: Palonosetron is a second generation serotonin antagonist usually used in a fixed dose of 75 mcg for the prophylaxis of postoperative nausea and vomiting.
- Trial name
- NCT02941913
- Testing
- palonosetron
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Obesity
Mechanisms Underlying Postoperative Insulin Resistance and Inflammation
Having an operation places an enormous burden on the body, leading to the development of inflammation and so called 'insulin resistance'.
- Trial name
- NCT01470534
- Testing
- carbohydrate drink, Muscle biopsy, Blood sampling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Nottingham
Obesity, Vasodilation
Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
- Conditions
- Obesity, Vasodilation, Healthy
- Trial name
- NCT05219799
- Testing
- Propranolol Hydrochloride, Isoproterenol, Phentolamine Mesylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overweight, Obesity
The Effects of Including Almonds in a Weight Loss Trial
The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and…
- Trial name
- NCT02360787
- Testing
- Energy restriction, Almonds (15% kcal/day)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Purdue University
Weight Gain, Women's Health
Preventing Weight Gain in African American Reproductive-Aged Women
The purpose of this research study is to evaluate the effect of a Facebook-delivered weight-gain prevention program versus a Facebook-delivered program with general women's health information.
- Conditions
- Weight Gain, Women's Health, Obesity
- Trial name
- FB--Pilot (NCT02416921)
- Testing
- Weight-gain Prevention, Women's Health
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Overweight, Obesity
Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males
The investigators propose to 1) assess the feasibility, acceptability and preliminary efficacy of a gender- and culturally-sensitive weight loss intervention in 48 overweight/obese Hispanic males ages 18-64 over 12 weeks; 2)…
- Trial name
- NCT02783521
- Testing
- Counseling sessions, Wait List Control
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obesity, Type 2 Diabetes
Probiotics as a Novel Approach to Modulate Gut Hormone Secretion and Risk Factors of Type 2 Diabetes and Complications
The investigators aim to test the hypothesis that Lactobacillus Reuteri-enriched microbiota improves insulin sensitivity and glucose tolerance in obese healthy and obese type 2 diabetes patients by improving gut hormone secretion…
- Trial name
- NCT01250106
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Obesity, Insulin Resistance
Endothelial Function in Young Hispanic Adults at Risk for Type 2 Diabetes
Diabetes is a major public health problem. Hispanics/Latinos are known to be at higher risk for type 2 diabetes. The function of the endothelium has played a key role in the understanding of vascular complications in people with…
- Trial name
- NCT01926938
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Morbid Obesity, Nutritional Deficiency
Nutritional Deficiencies in the Bariatric Patients
Although morbidly obese subjects have larger than regular caloric intake, there is evidence that they suffer from nutritional deficiencies at a higher rate than the general population, probably because they eat mostly "unhealthy…
- Trial name
- NCT00351338
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Morbid Obesity, Anesthesia Complication
Low Flow Anesthesia in Morbid Obesity
In this study to planned to research the efficacy of low-flow anesthesia on patients undergoing sleeve gastrectomy due to morbid obesity on respiratory functions after surgery by examining FEV1 and FVC values and FEV1/FVC ratio.
- Conditions
- Morbid Obesity, Anesthesia Complication, Anesthesia; Functional
- Trial name
- NCT03913858
- Testing
- Obesity Surgery with Low-Flow Anesthesia, Obesity Surgery with High-Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Ultrasound Quality
Can Increased Body Mass Index Prevent Adequate Ultrasound Examination for Trisomy 21 Risk Assessment?
Determine Cutoff BMI at which transabdominal sonography (TAS) is not satisfactory for aneuploidy risk assessment.
- Trial name
- NCT02443597
- Testing
- ultrasound
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Benha University
Obesity, Alcohol Dependence
Imaging of Cannabinoid 1 Receptors Using [11C]OMAR and PET
The aim of the present study is to conduct a human trial of [C-11]OMAR, a new PET imaging agent for the brain cannabinoid type 1 receptors (CB1), to determine its pharmacokinetics and binding characteristics.
- Conditions
- Obesity, Alcohol Dependence, High Stress
- Trial name
- NCT01719497
- Testing
- [C-11]OMAR
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Surgery
Obesity Alters Lung Mechanics in Robotic Surgery
Intraoperative lung protective ventilation strategies using standardized tidal volumes based on predicted body weight have proven beneficial, but attempts to standardize positive end expiratory pressure (PEEP) settings have not…
- Conditions
- Obesity, Surgery, Anesthesia
- Trial name
- NCT04329910
- Testing
- no intervention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Vermont Medical Center