Clinical trials: Adiposity
Obesity
MOTIVATE Weight Loss Study
The purpose of this study is to evaluate the impact of minor variations in Incisionless Operating Platform (IOP)procedural techniques on gastric emptying, hormone levels, satiety, and weight loss in the treatment of primary…
- Trial name
- MOTIVATE (NCT01679158)
- Testing
- Using The IOP system from USGI to place suture anchors
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- USGI Medical
Healthy
Increasing Physical Activity Levels in Low-Income Women
Regular physical activity is important for good health. Women, particularly women with low incomes, have many personal barriers to regular physical activity.
- Trial name
- NCT00065026
- Testing
- Physical activity opportunities for low-income women
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents
Large studies of children show that over half of the children in the United States of America do not have enough vitamin D stored in their bodies.
- Trial name
- NCT01217840
- Testing
- Drisdol (Ergocalciferol) Vitamin D2
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus, Obesity
Detemir Energy Expenditure Study
This is a study designed to compare the effects of 2 long-acting insulins, detemir and insulatard, on energy expenditure,weight, fat composition, gut hormone profiles, glycaemic control and fat and muscle gene expression over a 6…
- Trial name
- DEES (NCT00788840)
- Testing
- Insulatard, Detemir
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Surrey
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Obesity, Overweight
Metabolic Effect of New Foods Through Gut-brain Axis
A diet high in easily obtained energy-dense foods leads to the problems of overweight and obesity common in the developed world. Foods enriched with fiber or bitter compounds may increase satiety and decrease energy intake.
- Trial name
- CHECKMATE (NCT01851304)
- Testing
- Satiety of breads, Satiety of puddings
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obesity, Physical Inactivity
Effect of Health Education Intervention on Promoting Healthy Lifestyles for Undergraduate Female Students in Saudi Arabia
According to the World Health Organization (WHO), Saudi Arabia has seen a more astonishing rise in obesity. Young females have a considerable prevalence of unhealthy dietary practices and lack of knowledge about healthy and…
- Trial name
- NCT06150248
- Testing
- Education Intervention, No intervention
- Where
- Malaysia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Prader-Willi Syndrome
PWS European Blood Bank for Infants and Controls From 0 to 48 Months
The present project aims to determine the underlying mechanisms for the switch from failure to thrive to excessive weight gain and hyperphagia with impaired satiety in PWS.
- Trial name
- NCT02529085
- Testing
- blood samples
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Obesity, Endothelial Dysfunction
Effects of Body Mass Index on the Hyperemic Response to Regadenoson
We will test the hypothesis that a single dose of Regadenoson will produce equivalent degrees of coronary hyperemia in patients of widely different body size.
- Conditions
- Obesity, Endothelial Dysfunction, Decreased Vascular Flow
- Trial name
- NCT00859833
- Testing
- Adenosine, Regadenoson
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
COPD, Chest Wall Disease
Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure
This study is looking at whether there is a difference in outcomes using two different types of breathing support in those patients who have chronic respiratory failure (patients who under-breathe).
- Conditions
- COPD, Chest Wall Disease, Neuromuscular Disease, Obesity Hypoventilation
- Trial name
- NCT00994552
- Testing
- Pressure support ventilation, Pressure control ventilation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Opioid Use, Bariatric Surgery Candidate
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery.
- Conditions
- Opioid Use, Bariatric Surgery Candidate, TCI Eleveld, Obesity
- Trial name
- NCT07568938
- Testing
- opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Hepatitis
S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis
The purpose of this study is to examine the effect of S-adenosylmethionine therapy in those patients with non-alcoholic liver disease in the form of steatohepatitis (NASH).
- Trial name
- NCT00108589
- Testing
- S-adenosylmethionine
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Obesity
Assessment of the Impact of Body Position on Diaphragmatic Excursion in Obese Patients to Improve Proactice in Respiratory Kinesitherapy
The EXDECHO study is the first randomized study evaluating the effect of four body positions on diaphragmatic excursion in obese patients by ultrasound.
- Trial name
- EXDECHO (NCT05372250)
- Testing
- Measurement of the diaphragmatic excursion according to the position of the body by ultrasound
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Central Hospital, Nancy, France
Polycystic Ovary Syndrome
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
This study will be carried out in an attempt to know which is more effective, Intermittent fasting diet or resistive exercise program on insulin resistance in obese woman with polycystic ovarian syndrome.
- Trial name
- NCT06882291
- Testing
- Intermittent fasting diet, Resistive exercise program, Medical treatment
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Obesity
Signature Diagnostic of Non-alcoholic Steatohepatitis (NASH) by Infrared Light Spectroscopy
Evaluation of the diagnostic performance of an algorithm developed to detect metabolic profiles specific of non-alcoholic steatohepatitis NASH and based on the reading of a blood sample's infrared spectra
- Trial name
- SIGNALS (NCT03978247)
- Testing
- NASHMIR
- Where
- Belgium
- Volunteers
- 382 people
- Sponsor
- Diafir
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Anxiety, Obesity
Obesity and Mindful Eating in Patients With Anxiety
Background: Obesity is chronic disease with high prevalence rates, functional disability and difficult long-term management. Anxiety is one of the most common psychological disorders in obesity, and when associated with other…
- Conditions
- Anxiety, Obesity, Eating Behavior, Mindfulness
- Trial name
- OMETA (NCT06087185)
- Testing
- Mindful Eating, Video Group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obesity, Morbid, Bariatric Surgery Candidate
Trends and Safety in Revisional Bariatric Surgery in Italy
Background: Revisional bariatric surgery (RBS) represents a further solution for patients who experience an inadequate response following initial bariatric surgery or significant weight regain following an initial satisfactory…
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Remission, Complication,Postoperative
- Trial name
- NCT05194943
- Testing
- revisional bariatric surgical procedures
- Where
- 11 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Roma La Sapienza
Childhood Obesity
Testing Digital Technologies to Help Families Build Healthy Habits
The current study is a randomized pilot trial to test the feasibility of a psychoeducational virtual reality experience to increase motivation for behavior change among children with overweight or obesity.
- Trial name
- NCT04845568
- Testing
- Virtual Reality Experience
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Washington University School of Medicine
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development