Clinical trials: Adiposity
Obesity, Diabetes
Hypothalamic Function Before and After Bariatric Surgery
The purpose of this study is to determine the effect of gastric banding or gastric bypass on hypothalamic morphology and function, gut hormones and systems biology in obese subjects with and without type 2 diabetes.
- Trial name
- NCT01167959
- Testing
- Roux en Y gastric bypass and lap. gastric banding, Prodimed dietary intervention
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Migraine, Obesity
Behavioral Weight Loss as a Treatment for Migraine in Obese Women
This study involves a randomized controlled trial to test the efficacy of behavioral weight loss as a treatment for migraine in obese females aged 18 to 50 years.
- Trial name
- NCT01197196
- Testing
- Behavioral Weight Loss Intervention, Migraine Education
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity
Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men
Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will be measured with the microdialysis technique by measuring glycerol concentration and blood flow in abdominal adipose tissue.
- Trial name
- NCT02211391
- Testing
- Casein Protein
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Obesity
Effect of Different Weight Vests on Body Weight in Obese Individuals
Obesity related ailments, such as cardiovascular diseases (CVD) and metabolic disorders are major causes of death in the Western World.
- Trial name
- EVO (NCT03672903)
- Testing
- Weight Vest
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Obese Adolescents, Obesity
A Study of XW003 Injection in Chinese Adolescents With Obesity
The aim of the study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XW003 injection in Chinese adolescents with obesity
- Trial name
- NCT07143227
- Testing
- XW003 injection
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Obesity, Aging
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids.
Dysfunction of adipose tissue in obesity, inflammation and aging: mechanisms and effects of physical exercise and omega-3 fatty acids.
- Conditions
- Obesity, Aging, Inflammation
- Trial name
- OBELEX (NCT03300388)
- Testing
- Omega-3 (DHA-rich dietary supplement), Resistance training
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Maternal Morbidity
Obesity: Cesarean Health by Incision Placement
Hypothesis: A Pfannenstiel cesarean skin incision placed under the pannus (should a pannus exist) will have a higher maternal morbidity composite rate than a Cohen cesarean skin incision placed above the pannus (should a pannus…
- Trial name
- O-CHIP (NCT02909582)
- Testing
- Cohen Incision
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Arthroplasty, Overweight and Obesity
Healthy Living After Knee Replacement
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to…
- Trial name
- NCT05190666
- Testing
- PACE Weight Loss program, Chronic Disease Self-Management
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity
Probiotic for Weight Management in Overweight and Obese Adults
To evaluate the impact of pasteurized Akkermansia muciniphila Akk11 capsules versus placebo on body composition (including body weight, BMI, body fat percentage, waist-to-hip ratio, wrist circumference, visceral fat area, and…
- Trial name
- NCT07507929
- Testing
- Probiotic
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Complications Wounds, Negative Pressure Wound Therapy
Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial
Incisional negative pressure therapy (INPWT) has previously been shown in certain patient populations to decrease wound healing complications, decrease the rate of hematomas and seromas, as well as have better scar quality.
- Conditions
- Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional
- Trial name
- NCT03010137
- Testing
- Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Maternal Obesity Syndrome
Hormonal Regulation of Postpartum Weight and Presence of Gut Peptides in Human Milk
Hormonal Regulation of Postpartum Weight and Presence of Gut Peptides in Human Milk Studies suggest that childbearing is an important contributor to the development of obesity in many women and that breastfeeding may be…
- Trial name
- NCT01514539
- Testing
- cross-sectional
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Obesity, Cardiovascular Disease
Healthy Bodies, Healthy Hearts: A Physical Activity Intervention Trial
The overall aim of Healthy Bodies, Healthy Hearts research study is to promote physical activity in women aged 45-65 years to promote reduced risk of cardiovascular disease.
- Conditions
- Obesity, Cardiovascular Disease, High Blood Pressure
- Trial name
- HBHH (NCT01099007)
- Testing
- In Person, At Home
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity
Functional Lipids and Appetite Regulation
To evaluate the short-term effects of structured lipids on appetite regulation.
- Trial name
- NCT00259259
- Testing
- SALATRIM
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Narcolepsy
Body Weight Regulation in Patients With Narcolepsy
This study will measure energy expenditure (the rate at which the body burns calories), physical activity and caloric intake in people with narcolepsy to learn more about how the risk of becoming overweight or diabetic may be…
- Trial name
- NCT00283894
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Rett Syndrome, Prader-Willi Syndrome
Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW
This study will investigate sleep behavior in subjects with Angelman Syndrome, Rett Syndrome or Prader-Willi Syndrome. The study will also investigate sleep behavior in healthy siblings of subjects with Angelman Syndrome, Rett…
- Conditions
- Rett Syndrome, Prader-Willi Syndrome, Angelman Syndrome, Sleep Problems
- Trial name
- RDCRN (NCT02670694)
- Where
- 9 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obesity
Portion Control Treatment for Obesity
To date, no studies have been published assessing the effectiveness of portion control interventions in a primary care setting. The investigators will conduct a pilot study to assess the effectiveness of an intervention including…
- Trial name
- NCT01451554
- Testing
- portion control plate, Usual Care
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Childhood
Acetaminophen Dosing in Obese Adolescents
Although there are numerous studies investigating the pharmacokinetic properties of intravenous acetaminophen in infants and children with normal weight, there are none in the obese pediatric patient .
- Trial name
- NCT03192566
- Testing
- Tylenol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Gene Abnormality
Endometrial Heparin-binding Epidermal Growth Factor Expression
Women with PCOS comprise a majority of fertility clinic attendees. Unfortunately, a high failure rate following fertility treatment was observed especially in obese women due to implantation failure.
- Trial name
- NCT04175002
- Testing
- utrogestan
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
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