Clinical trials: Adhesion Prevention, open to volunteers
Small Bowel Adhesion, Obstruction Bowel
Intestinal Obstruction Surgery. Acute Abdominal Pathology. №9:05/05/2026
Abstract and Study Objectives Adhesive small bowel obstruction (ASBO) is a common indication for surgical intervention. Intra-abdominal adhesions are the leading cause of small bowel obstruction, particularly in patients with a…
- Conditions
- Small Bowel Adhesion, Obstruction Bowel, Adhesiolysis, Laparoscopic Abdominal Surgeries
- Trial name
- AIO-S/AAP (NCT07905300)
- Testing
- surgical operation
- Where
- Kazakhstan
- Volunteers
- 1,500 people
- Sponsor
- Astana Medical University
Anterior Talofibular Ligament Injury
To Evaluate the Effectiveness of the Use of a Novel Crosslinking Hyaluronan Hydrogel on the Prevention of the Adhesion Occurrence After Anterior Talofibular Ligament Repair Surgery
The goal of this clinical trial is to evaluate the effectiveness of the use of a novel crosslinking hyaluronan hydrogel on the prevention of the adhesion occurrence after anterior talofibular ligament repair surgery.
- Trial name
- NCT06826898
- Testing
- DEFEHERE Absorbable Adhesion Barrier
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Talent Cro Inc.
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Endometriosis, Abdominal Adhesions
The Effect of Temporary Ovarian Suspension to the Abdominal Wall During Laparoscopic Endometriosis Surgery for Adhesion Prevention -A Comparative and Prospective Study
Pelvic adhesions, particularly between ovaries and pelvic sidewall, frequently complicate endometriosis surgery. Despite various interventions, no widely accepted solution exists.
- Trial name
- NCT07087756
- Testing
- laparoscopic ovarian suspension
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Carmel Medical Center
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Intrauterine Adhesion, Intrauterine Adhesions
To Evaluate the Safety and Effectiveness of Intrauterine Adhesion Preventer in the Prevention and Treatment of Intrauterine Adhesions, a Prospective, Multicenter, Randomized Controlled Clinical Trial
To evaluate the effect of uterine stents in preventing intrauterine adhesions after intrauterine operation and whether they meet the safety requirements for clinical use.
- Trial name
- NCT07611474
- Testing
- Uterine stent group, Uterine ring + balloon + sodium hyaluronate gel
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Intrauterine Adhesion
Heparin Solution Versus Anti-adhesion Barrier Gel for Intrauterine Adhesions Prevention After Operative Hysteroscopy
The aim of this study is to compare the efficacy of intrauterine application of heparin solution to the use of hyaluronic acid barrier gel for the prevention of intrauterine adhesion formation after operative hysteroscopy.
- Trial name
- NCT05257213
- Testing
- Heparin solution, Anti-adhesion barrier gel
- Where
- 2 sites in Bulgaria
- Volunteers
- 100 people
- Sponsor
- Nadezhda Women's Health Hospital
Prevention of Postoperative Adhesions
Effect of Intraperitoneal Insulin Administration After Laparoscopy in Insulin-Resistant Patients on Prevention of Postoperative Adhesion Recurrence: A Randomized Controlled Trial
Adhesion formation following laparoscopic pelvic surgery remains a significant cause of chronic pelvic pain, infertility, and surgical complications.
- Trial name
- NCT07007130
- Testing
- Actrapid insulin, Normal saline
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Retained Products of Conception
The Efficacy of Auto-cross Linked Hyaluronic Acid Gel in the Prevention of Adhesion Reformation After Hysteroscopic Resection of Retained Products of Conception
Retained product of conception (RPOC) is defined by abnormal trophoblastic persistence or retained placenta inside the uterus cavity after a pregnancy independently of the outcome. Untreated RPOC can compromise future fertility.
- Trial name
- NCT05085067
- Testing
- auto-crossed-linked hyaluronic acid gel
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology