Clinical trials: Adhesion
Polyetheretherketone
Microbial Adhesion to Metallic Versus Non Metallic Surfaces of Bounded Removable Partial Denture
a split mouth randomized clinical trial that compares quantity and quality of bacterial adhesion under both PEEK versus cobalt chromium alloy denture base.
- Trial name
- splitmouth (NCT03008317)
- Testing
- PEEK
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asherman Syndrome, Endometrial Polyp
Efficiency of INTERCOAT (Oxiplex/AP Gel) in Preventing Intrauterine Adhesion Formation in Hysteroscopic Surgery
The study purpose is to examine the influence of INTERCOAT in prevention of intra-uterine adhesions formation after any hysteroscopic surgery.
- Conditions
- Asherman Syndrome, Endometrial Polyp, Uterine Myoma
- Trial name
- NCT01637974
- Testing
- INTERCOAT administration
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Carmel Medical Center
Syringomyelia
Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia
To determine whether Subarachnoid-Subarachnoid (S-S) Bypass results in better patient outcomes with fewer complications and improved quality of life compared to intradural adhesion lysis in individuals with Spinal Arachnoiditis…
- Trial name
- NCT06375759
- Testing
- Subarachnoid-Subarachnoid (S-S) Bypass, Intradural Adhesion Lysis
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Adhesion
Safety and Tolerability of Seroguard Use
The performed study of safety and tolerability of Seroguard, solution (JSC Pharmasyntez, Russia) in patients, undergoing planned laparoscopic cholecystectomy, demonstrated that patients from the both groups had the similar safety…
- Trial name
- NCT03640559
- Testing
- Seroguard
- Volunteers
- 50 people
- Sponsor
- Pharmasyntez
Thalassemia, Sickle Cell Disease
Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
Allogeneic blood and marrow transplantation remains the only viable cure for children who suffer from many serious non-malignant hematological diseases. Transplantation, however, carries a high risk of fatal complications.
- Conditions
- Thalassemia, Sickle Cell Disease, Glanzmann Thrombasthenia, Wiskott-Aldrich Syndrome
- Trial name
- NCT01319851
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Low Back Pain, Cesarean Section Complications
Osteopathic Manipulations of Post Cesarean Section Adhesions on Low Back Pain
Chronic low back pain post cesarean section adhesions represents a restricting dysfunction, mainly influences abdominal fascia that leads to major welfare and economic restrictions.
- Trial name
- NCT06907394
- Testing
- Osteopathic Manipulations, Control Group
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Sickle Cell Disease
Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD)
An open label, prospective, randomized cross-over phase II study in up to 60 sickle cell patients who are either homozygous for Hb S or have HbSB0 thalassemia.
- Trial name
- NCT01077921
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Laura M. De Castro, MD
Intrauterine Adhesion
Intrauterine Stent Placement Following Hysteroscopic Septum Resection
The study hopes to learn the best way to prevent internal scar tissue after septum removal. The use of an intrauterine foley catheter balloon may prevent the formation of adhesions following surgery.
- Trial name
- NCT07032506
- Testing
- Intraoperative placement of an inflated intrauterine pediatric foley catheter, No Catheter placement, Hormonal Therapy Agent
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Weill Medical College of Cornell University
Colon Cancer
The Impact of Inflammatory Adhesion on the Prognosis of Colon Cancer Patients
The purpose of this study is to explore the impact of tumor-associated inflammatory adhesion on the prognosis of colon cancer patients.
- Trial name
- NCT06655285
- Testing
- This was a retrospective study and no patient intervention was performed.
- Where
- China
- Volunteers
- 229 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Acute Cholecystitis With Chronic Cholecystitis
Correlation Between Power Doppler and Intraoperative Findings of Chronic and Acute Cholecystitis
In theory, increased vascularity of GB wall could be associated with intraoperative findings, such as, GB wall inflammation and accompanying adhesions.
- Trial name
- NCT02156947
- Testing
- Laparoscopic cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun Education and Research Hospital
Surgical Adhesions, Blood Loss, Surgical
Pilot Study Differential Dissector™ for Blunt Dissection
The primary purpose of this study is to evaluate the quality of blunt dissection during abdominal and pelvic surgery involving dissection of adhesions, separation of blood vessels and neurovascular structures while preserving the…
- Trial name
- NCT02382952
- Testing
- Differential Dissector, Standard Dissection Method
- Sponsor
- University of North Carolina, Chapel Hill
Multiple Sclerosis
Analysis of Lymphocyte Cell Surface Adhesion Marker Expression in Natalizumab Population With Active Control
The purpose of the study is to research the association between receiving Tysabri® (natalizumab), interferon beta-1a, glatiramer acetate or not having any treatment for your MS and how it may or may not impact certain white blood…
- Trial name
- NCT01626248
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- John F. Foley, MD
Small Bowel Obstruction, Small Bowel Adhesion
Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction
This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.
- Conditions
- Small Bowel Obstruction, Small Bowel Adhesion, Strangulation of Ileum
- Trial name
- COTACSO (NCT03139149)
- Testing
- Adhesiolysis, X-ray diagnostics, Computer tomography
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Symptomatic Vitreomacular Adhesion
A Phase III Study of A01016 in Subjects With Symptomatic Vitreomacular Adhesion
The purpose of this study is to evaluate the superiority regarding vitreomacular adhesion (VMA) resolution of a single intravitreal injection of A01016 (Ocriplasmin) compared to sham-injection in subjects with symptomatic VMA.
- Trial name
- NCT01889251
- Testing
- Ocriplasmin
- Where
- Japan
- Volunteers
- 251 people
- Sponsor
- Alcon Research
Placenta Retained, Uterine Diseases
Effectiveness of Hyaluronic Acid Gel in the Prevention of Intrauterine Adhesions After Second Trimester Abortion
This prospective, randomized, controlled study evaluates the efficacy of self-crosslinked hyaluronic acid gel to prevent the development of de-novo intrauterine adhesions following curettage for retained product after second…
- Trial name
- NCT02868437
- Testing
- intrauterine self-cross-linked hyaluronic acid gel
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Age Related Macular Degeneration, AMD
Study of Efalizumab Combined With Intravitreal Ranibizumab in the Treatment of Age-Related Macular Degeneration
Efalizumab is an immunosuppressive recombinant humanized IgG1 monocolonal antibody (150 Kd) that binds to human CD11a (1) and is used for the treatment of plaque psoriasis.
- Conditions
- Age Related Macular Degeneration, AMD, CNV
- Trial name
- SEIRA (NCT00726466)
- Testing
- Efalizumab, Ranibizumab
- Where
- United States
- Sponsor
- Vitreous -Retina- Macula Consultants of New York
Myoma;Uterus
Prevalence of Intrauterine Adhesions After Myomectomy
This prospective, multicenter, observational study evaluated the prevalence of intrauterine adhesions after laparoscopic or laparotomic myomectomy and investigated clinical and surgical factors associated with their occurrence.
- Trial name
- NCT04030273
- Testing
- Diagnostic hysteroscopy
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Università degli Studi dell'Insubria
Intrauterine Adhesions, Chronic Endometritis
Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions
This study is to evaluate the prevalence of chronic endometritis (CE) in women with severe intrauterine adhesions and compare recurrence of adhesion in women with and without CE.
- Trial name
- NCT02744807
- Testing
- Chronic endometritis
- Volunteers
- 125 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Sickle Cell Disease
Hemoglobin Desaturation in Sickle Cell Disease
As part of routine care for SCD, some people are found to have low oxygen levels (≤ 88%) while sleeping, at rest, or with exercise.
- Trial name
- NCT03908385
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University Hospitals Cleveland Medical Center
Healthy
Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Generic Lidocaine Patch 5% in Healthy, Adult, Human Subjects
An open label, randomized, two-treatment, two-period, single-dose study evaluating the product adhesion in healthy, adult subjects using ZTlido 1.8% Topical System and a generic Lidocaine Patch 5%
- Trial name
- NCT04319926
- Testing
- lidocaine topical system 1.8%, lidocaine patch 5%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.