Clinical trials: Addictive Behavior, open to volunteers
Pregnancy
Social Media Withdrawal in Pregnancy: Effects on Maternal Mental Health and Misinformation
The goal of this clinical trial is to learn if restricting social media use with a hardware device can improve mental health and well-being during pregnancy.
- Trial name
- SWIPE LEFT (NCT07812506)
- Testing
- Brick device
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Problematic Internet Use
Group-based IMPROVE Therapy for Problematic Internet Use in University Students
Problematic internet use (PIU) is a growing behavioral health concern among university students. This study aims to evaluate the effectiveness and psychological mechanisms of "IMPROVE," a manualized, multimodal group-based…
- Trial name
- IMPROVE-PIU (NCT07434778)
- Testing
- IMPROVE Program, Digital Psychoeducation Newsletters
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sir Run Run Shaw Hospital
Smoking (Tobacco) Addiction
Impact of Exercise Associated With Cognitive-behavioral Therapy in Smokers
Smoking remains one of the leading causes of global morbidity and mortality, responsible for more than 8 million deaths annually, according to data from the World Health Organization.
- Trial name
- NCT07186049
- Testing
- Thesis Sessions, General Health Guidelines, Thesis and Exercises
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Agnaldo José Lopes
Alcohol Use Disorder, Alcohol Use Disorder (AUD)
Optimizing Smart Technology for Addiction Recovery
The goal of this study is to develop a machine-learning guided recovery messaging system. The main question it aims to answer is can messages be used to: help people to improve their health make changes in people's lives to…
- Trial name
- STAR (NCT07573540)
- Testing
- STAR
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- University of Wisconsin, Madison
Stroke
Addiction & Stroke
Modifiable stroke risk-factors, which include poor lifestyle habits, account for 90 % of the risk of stroke. Disability Adjusted Life Years (DALYs) related to cerebrovascular disorders rely on three main factors, including the…
- Trial name
- ADDICT-STROKE (NCT06187025)
- Testing
- Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), Ecological Momentary Assessment (EMA)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
Alcohol Use Disorder, Hazardous Alcohol Use
LDART for Alcohol Use Disorder
This study is a pilot randomized controlled trial to evaluate feasibility, acceptability, and preliminary efficacy of a digital intervention called Let's Do Addiction Recovery Together! (LDART) in adults with alcohol use…
- Trial name
- LDART (NCT07221383)
- Testing
- LDART, Psychoeducational control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Problematic Use of Mobile Phones
Cognitive Behavioral Therapy for Mobile Phone Addiction in Hospitalized Patients
Problematic mobile phone use is excessive dependence and use of electronic products and their functions, which affects the daily life of users.
- Trial name
- CBT (NCT07457658)
- Testing
- Cognitive-behavioral therapy, Traditional treatment in the ward
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sir Run Run Shaw Hospital
4-STEP-Training Program for Social Media Addiction
The Effectiveness of 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and Psychological Problems Among Adolescence
This study evaluates the effectiveness of the 4-STEP Training Program in reducing social media addiction and improving psychological well-being among adolescents.
- Trial name
- 4-STEP-TPS (NCT07564115)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Drug Misuse, Addiction
Construction of a Risk Screening Tool for New Psychoactive Substance Misuse Among Adolescents and Young Adults
The goal of this observational study is to construct a risk tool available for screening young adults and adolescents at high risk of drug misuse and provides a chance for early intervention to young adults and adolescents at…
- Trial name
- NCT06714578
- Testing
- Questionnaire and Physical Exam
- Where
- China
- Volunteers
- 1,035 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Opioid Abuse (Disorder), Clinical Decision Support
Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3
This study is stage 2, round 3 of a larger study which refines and optimizes the EMBED clinical decision support (CDS) to increase number of ED physicians following standard of care for the administration of buprenorphine to…
- Trial name
- NCT07793383
- Testing
- Refined EMBED CDS, Provider alert that nurse completed COWS
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Social Media Addiction, Anxiety
Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention
The investigators will be randomizing 300 college student participants with high levels of social media use into either a 1) control condition (no intervention), a 2) mindfulness meditation cognitive intervention, or 3) a social…
- Conditions
- Social Media Addiction, Anxiety, Depression Disorder, Wellbeing
- Trial name
- SMUS (NCT07097545)
- Testing
- Mindfulness, Social Media Reduction, Exercise
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Mammary Cancer
Omission of Surgery and Sentinel Lymph Node Dissection in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti- HER2-based Neoadjuvant Therapy (ELPIS Trial)
This is a prospective, single arm, open-label, exploratory study in women with primary operable HER2-positive, HER2-enriched(HER2-E)/ERBB2-high breast cancer according to PAM50 intrinsic subtype and a ERBB2 pre-defined cutoff…
- Trial name
- ELPIS (NCT04301375)
- Testing
- Pertuzumab and trastuzumab FDC subcutaneous, Paclitaxel, TDM1
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- David Garcia Cinca
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Internet Gaming Disorder
Evaluation of Interventions to Promote Work-Life Balance Among Students at Gaming Schools
Introduction : Internet Gaming Disorder (IGD) affects an estimated 14% of French adolescents, with consequences ranging from sleep disorders and academic failure to social and mental health difficulties.
- Trial name
- JERRI (NCT07887659)
- Testing
- Online health promotion interventions for gaming school students, In person health promotion interventions for gaming school students
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
People Who Use Opioids/People With Opioid Use Disorder (OUD)
Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support
In the U.S., an estimated 3.6 million people who inject drugs (PWID) face a growing yet preventable health crisis, with rising cases of serious injection-related infections (SIRI), including HIV, due to limited access to two…
- Trial name
- P2PH (NCT07073924)
- Testing
- Implementation strategy bundle
- Where
- 4 sites in United States
- Volunteers
- 536 people
- Sponsor
- University of Pittsburgh
Addiction, SMARTPHONE OWNER
Mobile Restriction on Dopamine Transporter
Restriction of mobile phone use for 2wks and undergo PET scanning for DAT bindinng. Free use of mobile phone use for 2wks and undergo PET scanning for DAT bindinng.
- Trial name
- NCT07663474
- Testing
- Mobile phone restrction
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Opioid Use Disorder
PRoducing Outcome Measures for OTP Quality Improvement
This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet many people leave treatment early.
- Trial name
- PROMOTE-QI (NCT07214389)
- Testing
- Quality Measures (Audit and Feedback), Quality Improvement (QI) Toolkit, External QI Facilitation
- Where
- United States
- Volunteers
- 4,500 people
- Sponsor
- RTI International
Alcohol Addiction, Alcoholism
A Trial to Investigate the Effects of Cannabidiol Plus Naltrexone on Alcohol Craving in Patients With Alcohol Dependence
Alcohol addiction (AD) is a chronic relapsing disorder with currently limited pharmacological treatment options. Alcohol craving, a hallmark symptom of AD that drives relapse in patients, is only insufficiently treated by…
- Trial name
- ICONICplus (NCT06845124)
- Testing
- Cannabidiol capsules, Naltrexone (drug)
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation.
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT05276050
- Testing
- active F8-coil delivered rTMS, active H-coil delivered rTMS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston