Clinical trials: Addiction
Drug Dependence, Alcohol Dependence
Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits
Addiction to illicit and prescribed drugs, alcohol and tobacco is associated with a panoply of brain changes that contribute to structural and micro-structural deficits, altered metabolism and neurotransmission, and related…
- Trial name
- NCT01171677
- Testing
- IntenSati
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Food Addiction, Withdrawal
The Biobehavioral Impact of Diet Quality on Affect and Craving
The current study experimentally investigates whether reducing highly processed (HP) foods (defined in this study as foods high in added sugars) leads to, psychological and / or behavioral indicators of withdrawal.
- Trial name
- NCT04105712
- Testing
- Dietary Change (low in highly processed foods)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Michigan
IBS - Irritable Bowel Syndrome
Study on the Relationship Between Mobile Phone Addiction and Functional Gastrointestinal Disorders
A cross-sectional study was conducted to collect the relevant data of college students' mobile phone addiction and FGIDs (IBS, FD) in the form of questionnaire, so as to understand the situation of college students' mobile phone…
- Trial name
- NCT04817683
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Opiate Addiction
Lofexidine for Inpatient Opiate Detox
The main objective of this study is to investigate the effectiveness of lofexidine in reducing withdrawal symptoms among subjects undergoing opiate detoxification.
- Trial name
- NCT00235729
- Testing
- Lofexidine
- Where
- 16 sites in United States
- Volunteers
- 264 people
- Sponsor
- US Department of Veterans Affairs
Opiate Addiction, Borderline Personality Disorder
Evaluation of DBT Compared to Drug Counseling for Opiate Addicts
The purpose of this study is to compare a one year treatment program of Dialectical Behavior Therapy (DBT) + suboxone for opiate addicted individuals meeting criteria for borderline personality disorder (BPD) to a one year…
- Trial name
- NCT00117741
- Testing
- Dialectical Behavior Therapy, Drug Counseling
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Washington
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Addiction, Addiction Disorders
Effects of Breathwork and Meditation on Addiction Recovery
Emotional wellness can play a vital role in supporting recovery from substance use disorder (SUD). Developing skills to regulate emotions and manage stress during early stages of recovery can help manage triggers and prevent…
- Trial name
- NCT07510256
- Testing
- SKY Breathing Program
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Nicotine Dependence
Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment
The purpose of this research study is to determine whether combining electronic nicotine delivery systems (ENDS) with nicotine patch treatment will augment abstinence rates compared to either treatment alone.
- Trial name
- ENDS-P50 (NCT02487953)
- Testing
- Nicotine patch, ENDS
- Where
- United States
- Sponsor
- Duke University
Mammary Cancer
Omission of Surgery and Sentinel Lymph Node Dissection in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti- HER2-based Neoadjuvant Therapy (ELPIS Trial)
This is a prospective, single arm, open-label, exploratory study in women with primary operable HER2-positive, HER2-enriched(HER2-E)/ERBB2-high breast cancer according to PAM50 intrinsic subtype and a ERBB2 pre-defined cutoff…
- Trial name
- ELPIS (NCT04301375)
- Testing
- Pertuzumab and trastuzumab FDC subcutaneous, Paclitaxel, TDM1
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- David Garcia Cinca
Cocaine Dependence
Clinical Neurobiology of Serotonin and Addiction
The purpose of this study is to examine the relationship between 5-HT2R function, impulsivity and cue reactivity in cocaine dependent subjects and healthy controls and examine specific effects of escitalopram and mirtazapine on…
- Trial name
- NCT00732901
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Drug Addiction, Stimulant Dependence
CRAFT Behavior Therapy: Treatment Entry Component
This research compares the benefits of the original treatment, Community Reinforcement and Family Training (CRAFT), with the Treatment Entry Training (TEnT) component of CRAFT to determine if TEnt alone can produce the primary…
- Conditions
- Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence
- Trial name
- NCT00842036
- Testing
- Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Treatment Research Institute
Tobacco Addiction
Interventional Study on Smoking Reduction in Psychiatry
The smoking rate among people with mental disorders is higher than in the general population. Greater exposure to the harmful effects of tobacco partly explains the major inequality in life expectancy observed among people with…
- Trial name
- TABAPSY (NCT06926153)
- Testing
- TABAPSY, Usual Care
- Where
- 22 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people
- Sponsor
- GCS-CCOMS
Young Adult
The Effect of Smartphone Addiction on Physical Activity and Depression in University Students
This study was planned considering that young people with smartphone addiction are depressed and their physical activity is significantly reduced.
- Trial name
- NCT04606277
- Testing
- Smartphone addiction scale, physical activity scale and depression questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Behavior, Addictive, Cocaine Abuse
Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2
The purpose of this study is to determine whether long-term exposure to the Therapeutic Workplace intervention could sustain drug abstinence over an extended period of time in heroin- and cocaine-dependent, unemployed…
- Conditions
- Behavior, Addictive, Cocaine Abuse, Cocaine Dependence, Heroin Dependence
- Trial name
- NCT00249457
- Testing
- Contingency management
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Addiction, Substance, COVID-19
Evolution of Psychoactive Substances Consumption in Connection With COVID-19 Containment
The current containment linked to COVID-19 will have consequences for people suffering from addiction and there is a risk of overdoses when the containment ends.
- Trial name
- EPILOGUE (NCT04343339)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Opioid Use Disorder, Criminal Justice
Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews
This qualitative study investigates the potential benefits and challenges of using a once-a-month injectable medication, known as extended-release buprenorphine (XR-B), to treat individuals with opioid use disorder (OUD) within a…
- Conditions
- Opioid Use Disorder, Criminal Justice, Treatment Adherence and Compliance
- Trial name
- NCT06354465
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Lifespan
Drug Addiction, Drug Abuse
Impact of Online Patient Feedback (OQ) to Therapist
Dropout represents one of the largest problems in substance abuse treatment. International and Nordic research show that only 20 - 40 % of substance abusers complete treatment as intended.
- Trial name
- NCT01891045
- Testing
- OQ-45.2 no feedback, OQ-45.2
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- Oslo University Hospital
Smoking (Tobacco) Addiction
Addiction Potential of Very Low Nicotine Filtered Little Cigars
The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users.
- Trial name
- LOWFLC (NCT06630728)
- Testing
- Reduced Nicotine Content Cigars, Normal nicotine content cigar, Usual brand cigar
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Acute Musculoskeletal Pain, Chronic Pain
The Pain Intervention Via Video Optimization Trial
This project tests a brief evidence-based video to help educate patients regarding effective and safe pharmacologic and non-pharmacologic therapies for acute musculoskeletal pain (MSP).
- Trial name
- PIVOT (NCT06035575)
- Testing
- Educational video
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of North Carolina, Chapel Hill
Addiction
Trajectories and Reactions of Users and Relatives Consulting French Youth Addiction Services
In France, the "Consultations Jeunes Consommateurs" (CJC) are the services specialized in the reception of young people for addiction problems. There are more than 500 CJCs throughout France.
- Trial name
- TRYAD (NCT05609474)
- Where
- France
- Volunteers
- 1,430 people
- Sponsor
- Hôpital le Vinatier