Clinical trials: Acute Recurrent Pancreatitis
Recurrent Acute Pancreatitis
ERCP in Idiopathic Recurrent Acute Pancreatitis
The therapeutic impact of ERCP with sphincterotomy in the management of patients with idiopathic recurrent acute pancreatitis (RAP) needs further study.
- Trial name
- NCT01583517
- Testing
- Biliary sphincterotomy, Pancreatobiliary sphincterotomy
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Indiana University
Pancreatitis, Acute Pancreatitis
Fibro-inflammatory Progression From Acute to Chronic Pancreatitis
Observational prospective study evaluating the developement of chronic pancreatitis based on imaging modalities as well as biochemical markers of inflammation, fibrosis and oxidative stress.
- Conditions
- Pancreatitis, Acute Pancreatitis, Recurrent Pancreatitis, Chronic Pancreatitis
- Trial name
- NCT03853447
- Testing
- Diagnostic imaging
- Where
- 3 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Pancreatitis, Acute
Effects of a Peripherally Acting µ-opioid Receptor Antagonist on Recurrent Acute Pancreatitis
This study will investigate the effect of a peripheral acting opioid antagonist (PAMORA) on the disease course of patients with recurrent acute inflammation of the pancreas (acute pancreatitis).
- Trial name
- NCT04966559
- Testing
- Naldemedine 0.2 MG Oral Tablet
- Where
- 5 sites in Denmark, Sweden
- Volunteers
- 74 people
- Sponsor
- Asbjørn Mohr Drewes
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management
The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children.
- Trial name
- NCT06068426
- Testing
- Transabdominal ultrasound Shear wave elastography
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- David Vitale MD
Pancreatic Diseases
PAncreatic Disease Cohort of TOuLouse
This study is a prospective cohort dedicated to pancreatic diseases excluding cancer. The aim is to develop positive or differential diagnostic tools between benign potentially malignant or malignant pancreatic pathologies.
- Trial name
- PACTOL (NCT05824403)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Recurrent Acute Pancreatitis
Efficacy of ERCP in the Diagnosis and Treatment of Idiopathic Recurrent Acute Pancreatitis
The goal of this clinical trial is to learn if endoscopic retrograde cholangiopancreatography (ERCP) works to treat idiopathic recurrent pancreatitis (IRAP) in adults.
- Trial name
- ESPRIT (NCT06364397)
- Testing
- ERCP, Health education and conservative management of clinical routines
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Changhai Hospital
Gastric Outlet Obstruction, Biliary Obstruction
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
This registry aims to analyze long-term outcomes of therapeutic EUS (T-EUS) procedures, as well as to describe clinical and technical variables potentially predicting clinical success or adverse events, for a better selection of…
- Conditions
- Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
- Trial name
- PROTECT (NCT04813055)
- Testing
- Therapeutic EUS, Percutaneous Procedures, Surgical Interventions
- Where
- Italy
- Volunteers
- 510 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Pancreatitis, Recurrent Acute Pancreatitis
Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation
Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of…
- Trial name
- REAPPEAR (NCT04647097)
- Testing
- Standard intervention only, Standard intervention plus repeated intervention
- Where
- Hungary
- Volunteers
- 364 people
- Sponsor
- University of Pecs
Pancreatitis, Pancreas Divisum
SpHincterotomy for Acute Recurrent Pancreatitis
The purpose of this study is to determine if a procedure called Endoscopic Retrograde CholangioPancreatography (ERCP) with sphincterotomy reduces the risk of pancreatitis or the number of recurrent pancreatitis episodes in…
- Conditions
- Pancreatitis, Pancreas Divisum, Pancreatitis, Acute, Pancreatitis Idiopathic
- Trial name
- SHARP (NCT03609944)
- Testing
- ERCP with miES, EUS
- Where
- 21 sites in United States, Canada
- Volunteers
- 181 people
- Sponsor
- Oregon Health and Science University
Pancreatitis, Chronic, Pancreatitis, Acute
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus
The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis (RAP) or Acute Pancreatitis…
- Conditions
- Pancreatitis, Chronic, Pancreatitis, Acute, Diabetes Mellitus
- Trial name
- PEP-DM (NCT06729996)
- Testing
- Pioglitazone (PIO), Empagliflozin (EMPA)
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Pancreatitis
Acute Pancreatitis and Acute Fluid Collections
The purpose of this study is to evaluate if percutaneous drainage of sterile fluid collections recurring after initial aspiration in acute pancreatitis yielded better results than their conservative management.
- Trial name
- NCT00786929
- Testing
- Catheter drainage, Conservative treatment
- Where
- Bosnia and Herzegovina
- Volunteers
- 63 people
- Sponsor
- University Medical Center, Tuzla
Pancreatitis, Chronic, Pancreatitis, Acute Recurrent
Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain
Pain is the cardinal symptom of acute recurrent and chronic pancreatitis, and available medical treatments have limited efficacy.
- Trial name
- IMPACT (NCT03322644)
- Testing
- Internet-based CBT intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Seattle Children's Hospital
Acute Pancreatitis
Simvastatin in Reducing Pancreatitis in Patients With Recurrent, Acute or Chronic Pancreatitis
This randomized phase II trial studies how well simvastatin works in reducing pancreatitis (the inflammation of the pancreas) in patients with pancreatitis that occurs more than once (recurrent), has worsened quickly (acute), or…
- Trial name
- NCT02743364
- Testing
- Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Pancreatitis
The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis
Acute pancreatitis (AP) may develop to chronic pancreatitis (CP). In Finland, the ethiology is alcohol in about 80% of the cases.
- Trial name
- NCT02965898
- Testing
- Vitamin D 100ug, Vitamin D 10ug
- Where
- Finland
- Volunteers
- 260 people
- Sponsor
- Tampere University Hospital
Pancreatitis, Chronic, Pancreatitis, Acute
Pediatric Longitudinal Cohort Study of Chronic Pancreatitis
The investigators will enroll a total of 628 patients under 18 years of age with ARP or CP. Included in the total are the 357patients in the INSPPIRE 1 database who are planned to be reenrolled under this protocol over the next 4…
- Trial name
- INSPPIRE 2 (NCT03672422)
- Testing
- Blood sample, Patient questionnaires, Saliva sample
- Where
- 22 sites in United States, Australia and 2 more
- Volunteers
- 623 people
- Sponsor
- Aliye Uc
Acute Pancreatitis Necrotizing
Impact of Transmural Plastic Stent on Recurrence of Pancreatic Fluid Collection After Metal Stent Removal in Disconnected Pancreatic Duct
Walled of necrosis (WON) is severe local complication of acute necrotizing pancreatitis. Disconnected pancreatic duct syndrome(DPDS) is commonly seen (50-60%) after necrotizing pancreatitis and has long term implication like…
- Trial name
- NCT03436043
- Testing
- Transmural Plastic stenting
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Asian Institute of Gastroenterology, India
Hypertriglyceridemia Induced Acute Pancreatitis, Recurrent Acute Pancreatitis
GLP-1 Agonists for Prevention of Recurrent Hypertriglyceridemic Acute Pancreatitis
Hypertriglyceridemia-induced acute pancreatitis (HTG-AP) is associated with a high risk of recurrence despite standard lipid-lowering therapy and lifestyle modification.
- Conditions
- Hypertriglyceridemia Induced Acute Pancreatitis, Recurrent Acute Pancreatitis, Pancreatitis Relapsing, Hypertriglyceridemia
- Trial name
- RECAP-GLP1 (NCT07617155)
- Testing
- Semaglutide
- Where
- China
- Volunteers
- 396 people
- Sponsor
- Peking Union Medical College Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Acute Pancreatitis, Acute Pancreatic Necrosis
coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis
Acute pancreatitis (AP) is an inflammatory disease of the pancreas, most commonly caused by gallstones, or excessive use of alcohol. It represents a management challenge and a significant healthcare burden.
- Conditions
- Acute Pancreatitis, Acute Pancreatic Necrosis, Acute Pancreatitis Due to Gallstones, Acute Pancreatic Fluid Collection
- Trial name
- MANCTRA-1 (NCT04747990)
- Testing
- Early Definitive Treatment
- Where
- 3 sites in Italy, Spain
- Volunteers
- 600 people
- Sponsor
- University of Cagliari