Clinical trials: Acute Pulmonary Embolism
Acute Pulmonary Embolism
Saline Contrast Electrical Impedance Tomography Method for Diagnosis of Acute Pulmonary Embolism
The goal of this observational study is to compare the consistency of saline contrast Electrical Impedance Tomography(EIT) method and Computed Tomography Pulmonary Angiography (CTPA) in diagnosing acute pulmonary embolism.
- Trial name
- ECTPED (NCT07190079)
- Testing
- Saline contrast Electrical Impedance Tomography method, Computed Tomography Pulmonary Angiography (CTPA)
- Where
- China
- Volunteers
- 343 people
- Sponsor
- Peking Union Medical College Hospital
Acute Lung Injury, Metabolic Disturbances
Acute Lung Injury After Cardiac Surgery: Pathogenesis
The purpose of the present study is to visualize the inflammatory response and coagulation disorders during cardiac surgery in order to identify possible predictors for acute lung injury postoperatively.
- Conditions
- Acute Lung Injury, Metabolic Disturbances, Inflammation, Coagulation; Intravascular
- Trial name
- ALI (NCT02475694)
- Testing
- No intervention
- Volunteers
- 50 people
- Sponsor
- Aalborg University Hospital
Pulmonary Embolism Acute
Vibrato Aspiration System - Simple, Intuitive Approach to Clot Removal in Acute Pulmonary Embolism - a Safety & Feasibility Study
The study is a prospective, single-arm, multicenter study to evaluate the safety and effectiveness of the Vibrato™ Aspiration System for aspiration mechanical thrombectomy in the treatment of acute PE.
- Trial name
- NCT07685522
- Testing
- Mechanical Thrombectomy
- Where
- 2 sites in Poland
- Volunteers
- 10 people
- Sponsor
- Vicora, Inc.
Pulmonary Embolism
Prognostic Value of Plasma Lactate Levels Among Patients With Acute Pulmonary Embolism
To prospectively investigate the association between plasma lactate concentration and short-term adverse outcomes in patients with acute PE.
- Trial name
- TELOS (NCT01908231)
- Where
- 4 sites in Italy, Spain
- Volunteers
- 330 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery
Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation
Multi-detector computer tomography protocol project: Chest imaging technique and case presentation.
- Conditions
- Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery, Double IVC, May-Thurner Syndrome
- Trial name
- NCT01206751
- Testing
- Chest imaging technique and case presentation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Active Cancer and Symptomatic or Incidental Pulmonary Embolism Without HESTIA Criteria
Home Treatment of Patients With Active Cancer and Acute Pulmonary Embolism Without HESTIA Criteria.
Main objective of this multisite randomised study aims to demonstrate in patients with active cancer and symptomatic or incidental PE without HESTIA criteria, that home treatment is non-inferior to hospitalisation as regards the…
- Trial name
- HOME-PEK (NCT07315347)
- Testing
- Home-treatment group
- Where
- 20 sites in France
- Volunteers
- 824 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Embolism
Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography
1. To asses regional RV function in patients presented with acute pulmonary embolism using speckle tracking echocardiography 2. To evaluate its relationship to long term mortality.
- Trial name
- NCT04609605
- Testing
- speckle tracking echocardiography
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pulmonary Embolism
Prognostic Model for Long-Term Cardiac Function After Pulmonary Embolism Based on Dynamic Electrocardial Signal and Circulating Biomarkers
Pulmonary embolism (PE) is a highly morbid and fatal cardiovascular disease. Right ventricular dysfunction (RVD) secondary to PE indicates a poor prognosis and serves as a critical basis for risk stratification.
- Trial name
- NCT06541353
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China-Japan Friendship Hospital
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Pulmonary Embolism, Chronic Obstructive Pulmonary Disease
Pulmonary Embolism as a Cause of COPD Exacerbations
The primary objective is to demonstrate the clinical benefits of an active strategy for the diagnosis and treatment of PE compared to usual care in patients with unexplained exacerbations of COPD who require hospital admission.
- Trial name
- SLICE (NCT02238639)
- Testing
- Diagnostic and therapeutic strategy: Highly sensitive D-dimer testing and, if positive, multidetector computed tomographic pulmonary angiography (MDCT).
- Where
- 19 sites in Spain
- Volunteers
- 746 people
- Sponsor
- Ministry of Health, Spain
Pulmonary Embolism
Reperfusion Treatment in Acute Pulmonary Embolism
International guidelines recommend immediate reperfusion with systemic thrombolysis (ST) as first-line treatment in high-risk pulmonary embolism (PE).
- Trial name
- PE-NORDIC (NCT07003646)
- Testing
- Catheter directed intervention, any device, Alteplase
- Where
- 13 sites in Denmark, Sweden
- Volunteers
- 220 people
- Sponsor
- Sahlgrenska University Hospital
Pulmonary Embolism Acute
Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness
The investigation is intended to evaluate the safety and effectiveness of the AlphaReturn Blood Management System when used in conjunction with the cleared AlphaVac MMA F1885 System for the treatment of acute pulmonary embolism.
- Trial name
- APEX-Return (NCT07280247)
- Testing
- AlphaReturn Blood Management System
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- Angiodynamics, Inc.
Pulmonary Embolism
Validation of Different Risk Assessment Strategies in Normotensive Pulmonary Embolism
A risk stratification in hemodynamically stable patients with acute pulmonary embolism (PE) is deemed necessary to guide patient management.
- Trial name
- NCT02843243
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Azienda Ospedaliera Cosenza
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Pulmonary Embolism With Acute Cor Pulmonale
Catheter-directed Thrombectomy in High and Intermediate-high Risk Pulmonary Embolism
Pulmonary embolism is one of the leading causes of cardiovascular death. Pulmonary embolism may be life-threatening condition with an estimated 30-day mortality rate about 10-30%.
- Trial name
- CATH-PE (NCT04473560)
- Testing
- Catheter-directed thrombectomy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences