Clinical trials: Acute Musculoskeletal Pain
Rheumatoid Arthritis, Psoriatic Arthritis
Impact of Cannabis on Pain and Inflammation Among Patients With Rheumatoid or Psoriatic Arthritis
This laboratory study will investigate the impact of cannabis on pain, affect, and inflammation among patients with rheumatoid or psoriatic arthritis (n = 76).
- Trial name
- NCT04269993
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Brown University
Acute Musculoskeletal Disease, Sprains
Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department
This study evaluates the addition of a lidocaine patch to ibuprofen in the treatment of acute musculoskeletal pains. Half of the participants will get only ibuprofen for their pain, while other half will receive lidocaine patch…
- Conditions
- Acute Musculoskeletal Disease, Sprains, Sprains and Strains, Injuries
- Trial name
- NCT03571737
- Testing
- Ibuprofen, Lidocaine Patch 4%
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Pain, Muscle, Pain, Acute
Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries
In the Emergency Department, there is no standard of care for pain medication distribution for children with an acute musculoskeletal injury when there is no fracture present.
- Trial name
- NCT05283434
- Testing
- Arnica
- Where
- 2 sites in United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Acute Pain, Bunion
Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain
This study evaluates the safety and effectiveness of Wafermine™ for post-bunionectomy or post-abdominoplasty pain over a 24 hours period.
- Conditions
- Acute Pain, Bunion, Abdominoplasty
- Trial name
- NCT03246971
- Testing
- Wafermine™ 50 mg, Wafermine™ 75 mg, Wafermine™ 25 mg
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- iX Biopharma Ltd.
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Shoulder Impingement Syndrome, Chronic Pain
Sensorimotor Cortex Excitability in Shoulder Impingement Syndrome
Shoulder pain is a common musculoskeletal system complaint, accounting for 7-34% of patients in the clinic. The most common shoulder problem is subacromial impingement syndrome (SIS).
- Conditions
- Shoulder Impingement Syndrome, Chronic Pain, Transcranial Magnetic Stimulation, Electroencephalography
- Trial name
- NCT05627986
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Hallux Valgus
Acute Effects of Prolonged Walking on Hallux Valgus
Hallux valgus is a progressive foot deformity characterized by lateral deviation of the great toe and medial displacement of the first metatarsal head.
- Trial name
- NCT07177768
- Testing
- Prolonged walking
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Fibromyalgia
Acute Effects of Exercise in Women With Fibromyalgia (FM)
The investigators previous studies of aerobic exercise in women with fibromyalgia (FM) have shown that exercise improves body functions and/or symptom severity in most patients, but not in all.
- Trial name
- NCT01592916
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Musculoskeletal Pain
A Phase 1 Clinical Trial DHP2306R1 and DHP2306R2 in Healthy Adult Volunteers
This phase 1 study is to evaluate the safety and pharmacokinetic drug interactions of DHP2306R1 and DHP2306R2 when administered alone and in combination in healthy conditions.
- Trial name
- NCT06395155
- Testing
- DHP2306R1, DHP2306R2
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Daehwa Pharmaceutical Co., Ltd.
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cartilage Diseases
Sampling Biomarkers in Meniscus Injury to the Knee
The diagnosis of clinically-significant meniscal tears of the knee remains challenging, and it is unknown why only some injuries become painful.
- Trial name
- NCT00836966
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Scuderi, Gaetano J., M.D.
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Exercise Induced Muscle Damage, Cryotherapy
Acute Cryotherapy on Musculoskeletal Function and Biomarkers
In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more…
- Trial name
- NCT07211412
- Testing
- Cryotherapy, Eccentric exercise-induced muscle damage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Musculoskeletal Disorders
Acute Effect of Topical Menthol on Neck Pain
Topical menthol gels are classified 'topical analgesics' and are used to relieve aching and tenderness of muscles and joints. However, double-blind randomized controlled trials are lacking.
- Trial name
- IRMA04 (NCT01542827)
- Testing
- Biofreeze
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center
Inflammation, Fascia; Inflammation
The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution
The goal of this study is to explore the impact of two types of yoga-based body stretching (mild and intense) on dynamic changes of Systemic Inflammatory Cytokines (SICs) and Specialized Pro-resolving Mediators (SPMs) in…
- Conditions
- Inflammation, Fascia; Inflammation, Musculoskeletal Pain, Lower Back Pain
- Trial name
- NCT04444102
- Testing
- Yoga-based stretching
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
Long COVID, Chronic Pain
Characterization of Long Covid Pain in Primary Care
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Prevalence data and the underlying mechanisms of such pain are very limited in the scientific literature.
- Conditions
- Long COVID, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT05894642
- Testing
- 0
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Shoulder Pain
The Acute Effect of Shoulder Kinesiology Taping on Dental Students
Research Objective and Participants' Role: We invite you to participate in a scientific study aimed at reducing the load on your shoulder region during dental clinical practice.
- Trial name
- NCT07393100
- Testing
- Kinesiology Taping
- Where
- Cyprus
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- European University of Lefke