Clinical trials: Acute Gastroenteritis
Acute Appendicitis, Acute Appendicitis Without Peritonitis
The Role of Preoperative HALP Score in Differentiating Complicated Acute Appendicitis
Acute abdomen is a frequently encountered clinical condition that can be fatal if not diagnosed early. Acute appendicitis is one of the causes of acute abdomen and is the most common clinical condition leading to acute abdomen…
- Conditions
- Acute Appendicitis, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess, Acute Appendicitis With Rupture
- Trial name
- Appendicitis (NCT07002671)
- Testing
- Appendectomy, blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 411 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Diverticulitis
Prospective Observational Analysis of Circulating Endocan Levels in Patients Presenting With Acute Diverticulitis
Quantify the level of endocan in blood samples collected from patients with acute diverticulitis in the emergency department. Determine if endocan levels are correlated with the severity of diverticulitis according to the WSES…
- Trial name
- DIVENDO (NCT07027007)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Ospedale San Raffaele
Abdominal Pain, Appendicitis
Right Iliac Fossa Treatment-Turkey Audit
Background: Acute appendicitis stands out as a frequently encountered surgical emergency. Despite decades of experience and research, the diagnosis remains a formidable challenge, particularly in young females experiencing acute…
- Conditions
- Abdominal Pain, Appendicitis, Appendicitis Acute
- Trial name
- RIFT-Turkey (NCT04614649)
- Where
- Turkey (Türkiye)
- Volunteers
- 3,358 people
- Sponsor
- Gazi University
Appendicitis Acute, Safety Issues
Review of Efficacy of Used ultraSonic Energy Device
Single-use medical instruments are intended by the manufacturers for single-use only or for single-patient-use only. Nevertheless, single-use instruments are being reused more than once in many countries around the world.
- Conditions
- Appendicitis Acute, Safety Issues, Complication of Surgical Procedure, Device Induced Injury
- Trial name
- REUSED (NCT04226482)
- Testing
- New Device, Used Device
- Where
- 2 sites in Croatia
- Volunteers
- 100 people
- Sponsor
- University of Split, School of Medicine
Acute Appendicitis
Management of Acute Appendicitis Pain in the Emergency Department
This study aims to compare the effectiveness of TAP (Transversus Abdominal Plane) block, ESPB (Erector Spinal Plane Block), and tramadol in preoperative pain management for patients diagnosed with acute appendicitis and…
- Trial name
- NCT06808087
- Testing
- Transversus abdominis plane blockage, Erector spinae plane blockage, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Colitis, Ulcerative
Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis
This study aims to examine patients with acute severe UC who are refractory to intravenous corticosteroids and determine whether a strategy of using upadacitinib first followed by infliximab in upadacitinib non-responders is…
- Trial name
- RESCUE UC (NCT06660693)
- Testing
- Upadacitinib Oral Product
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- McMaster University
Acute Appendicitis
Peritoneal Closure Versus Non Closure During Open Appendectomy
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early…
- Trial name
- NCT02803463
- Testing
- open appendectomy with peritoneal closure, open appendectomy without peritoneal closure
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Bezmialem Vakif University
Appendicitis Acute, Pediatrics
TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children
When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia.
- Conditions
- Appendicitis Acute, Pediatrics, Analgesia
- Trial name
- PABLO (NCT04969133)
- Testing
- Levobupivacaine Hydrochloride 2.5 MG/ML
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Acute Gastroenteritis, Diarrhea
Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon
Acute gastroenteritis is a common cause of hospitalization in children with significant socioeconomic burden on the health community, we will follow in this observational and analytical study the admitted cases of acute…
- Conditions
- Acute Gastroenteritis, Diarrhea, Rotavirus
- Trial name
- SAGE (NCT02177799)
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- Shaikh Ragheb Harb Hospital
Dehydration, Acute Gastroenteritis
Assessment of Volume Status by Bedside Ultrasound in Children With Acute Gastroenteritis
The purpose of the study is assessment of volume status by bedside ultrasound in children with acute gastroenteritis
- Trial name
- NCT03021109
- Testing
- Measurement of inferior vena cava diameters with ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Derince Training and Research Hospital
Acute Gastroenteritis, Upper Respiratory Tract Infections
Fermented Milk on the Appearance of Common Winter Infectious Diseases
Respiratory and gastrointestinal infections are common in children under the age of 4 years, especially after the start of schooling.
- Trial name
- NCT02367612
- Testing
- Fermented milk
- Where
- 3 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Federico II University
Diverticulitis
LapLAND Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis
The aim of the study is to compare patient outcome following standard of care (Hartmann's or resection with anastomosis and defunctioning stoma) and a 'new therapy' (laparoscopic lavage alone) for the treatment of acute…
- Trial name
- LapLAND (NCT01019239)
- Testing
- Laparoscopic Washout, Hartmann's Procedure/ Primary Resection and Anastomosis
- Where
- Ireland
- Volunteers
- 300 people
- Sponsor
- St Vincent's University Hospital, Ireland
Pregnancy Complications, Acute Appendicitis
Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Approximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes.
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT05085353
- Testing
- non-obstetric acute general surgical disease
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Methodist Health System
Appendicitis Acute, Pregnancy Related
Appendectomy During Pregnancy and Child Development
Maternal acute appendicitis during pregnancy is the most common abdominal surgical emergency. Long-term neurodevelopmental issues were scarcely reported.
- Conditions
- Appendicitis Acute, Pregnancy Related, Anesthetic Toxicity, Child Development
- Trial name
- NCT05759351
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- Clinical Hospital Centre Zagreb
Acute Appendicitis
TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods
Acute appendicitis is the most common abdominal surgical emergency in children and a frequent cause of pediatric emergency department visits.
- Trial name
- TACTILE (NCT07479849)
- Testing
- Score-based appendicitis risk classification in teleconsultation
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Angers
Diverticulitis, Colonic, Therapy
Probiotic After Acute Colonic Diverticulitis
The goal of this observational study is to assess the efficacy and safety of the probiotic Escherichia coli Nissle 1917 (EcN®, Ca.Di.Group S.p.A) in the treatment of symptomatic patients after an episode of both complicated and…
- Trial name
- NCT06040515
- Testing
- Probiotic Formula
- Where
- 12 sites in Italy
- Volunteers
- 145 people
- Sponsor
- Erasmo Spaziani
Gastroenteritis
A Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Participants With Nausea and Vomiting Due to Acute Gastroenteritis
The purpose of this study is to demonstrate that domperidone suspension plus oral rehydration therapy (ORT) is more effective than placebo plus ORT at reducing the symptoms of vomiting associated with acute gastroenteritis (AG)…
- Trial name
- NCT02699385
- Testing
- Oral Rehydration Therapy, Domperidone
- Where
- 29 sites in Austria, Belgium and 4 more
- Volunteers
- 10 people
- Sponsor
- Janssen-Cilag International NV
Intra-Abdominal Infections, Intestinal Obstruction
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
- Conditions
- Intra-Abdominal Infections, Intestinal Obstruction, Appendicitis Acute, Perforated Viscus
- Trial name
- CLI (NCT06901544)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Appendectomy, Appendicitis
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
The purpose of this study is to analyze Fitbit data to predict infection after surgery for complicated appendicitis and the effect this prediction has on clinician decision making.
- Conditions
- Appendectomy, Appendicitis, Appendicitis Acute
- Trial name
- i-DETECT (NCT06395636)
- Testing
- Infection-Prediction Algorithm
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Gastroenteritis
Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis
The investigators will study the efficacy and side effect profile of LGG, a probiotic, in pediatric patients with acute gastroenteritis.
- Trial name
- NCT01773967
- Testing
- LGG, micro-crystalline cellulose
- Where
- 10 sites in United States
- Volunteers
- 971 people
- Sponsor
- Washington University School of Medicine