Clinical trials: Acute Exacerbation of COPD
Pulmonary Disease, Chronic Obstructive
Calprotectin I Serum as a Diagnostic Marker
Lower respiratory tract infection is the most common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).
- Trial name
- NCT03474484
- Where
- Norway
- Volunteers
- 113 people
- Sponsor
- St. Olavs Hospital
Acute Exacerbation of COPD
Randomized Controlled Study of Programmed Weaning From NIV for AECOPD
Purpose of research:to explore a reasonable programmed withdrawal process of noninvasive ventilation and thereby reduce the duration of noninvasive mechanical ventilation in patients with acute exacerbations of chronic…
- Trial name
- NCT06014034
- Testing
- Programmed Weaning From Noninvasive Mechanical Ventilation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Chronic Obstructive Pulmonary Disease
Evaluation of FeNO During and Following Acute COPD Exacerbation
The purpose of this research study is to determine whether exhaled nitric oxide (FeNO) goes up during an acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) and whether the level of exhaled nitric oxide returns…
- Trial name
- NCT01761006
- Testing
- NIOX MINO®
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University
COPD
Usefulness and Efficacy of Telemonitoring of Patients With COPD
A substantial number of people with COPD suffer from exacerbations, which are defined as an acute worsening of respiratory symptoms.
- Trial name
- TLM_COPD (NCT06135025)
- Testing
- Telemonitoring
- Where
- Tunisia
- Volunteers
- 164 people
- Sponsor
- University of Monastir
COPD
A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD
This is a prospective study to assess the burden of existing or hidden cardiovascular (CV) and renal disease in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in a Hong Kong public hospital…
- Trial name
- NCT07344285
- Testing
- Intervention Group, Usual Care
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation
Short course of steroids in COPD exacerbation improves FEV1 and decreases the relapse rate. However, some concerns remain about using systemic steroids for all patients with acute exacerbation.
- Trial name
- NCT00531791
- Testing
- prednisone group, Advair group
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Laval University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Effect of Compound Sodium Chlorate and Aminophylline Tablets on Chronic Obstructive Pulmonary Disease(COPD).
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an important event in the management of chronic obstructive pulmonary disease.
- Trial name
- NCT04101500
- Testing
- Compound Ipratropium Bromide Solution(C1) for Inhalation, Compound Sodium Chlolate and Aminophylline Tablets(C2)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
COPD Exacerbation Acute
Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention
To examine the prevalence of humoral immunodeficiency in patients with Chronic Obstructive Pulmonary disease (COPD) by evaluating both immunoglobulin levels and vaccine responses.
- Trial name
- NCT05764993
- Testing
- CUVITRU - Ig subcutaneous human 20%, Standard Medical Therapy
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rochester General Hospital
Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Effectiveness and Feasibility of Delivering an Education Program to Patients With an Acute Exacerbation of COPD
The purpose of this study is to determine if it is effective and feasible to provide a chronic obstructive pulmonary disease (COPD) education program to patients admitted with an acute exacerbation of COPD.
- Trial name
- NCT02321215
- Testing
- Introductory Disease Education
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- West Park Healthcare Centre
Acute Exacerbation Copd
Impact of Air Quality on Exacerbations of COPD in the Somme
All COPD patients with a diagnosis of acute exacerbation in emergency room in University Hospital of Amiens-Picardie between 01/01/2017 and 31/12/2017.
- Trial name
- PolluBPCO (NCT03079661)
- Where
- France
- Volunteers
- 179 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pulmonary Disease, Chronic Obstructive
Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to assess whether administration of a bolus dose of MgSO4 (magnesium sulfate) plus standard therapy is superior to standard therapy alone for the management of Acute Exacerbations of Chronic Pulmonary…
- Trial name
- NCT02498496
- Testing
- Magnesium Sulfate
- Sponsor
- Hôpital de Verdun
COPD Exacerbation, Dyspnea
Palliation of Dyspnea With Mouth Piece Ventilation in AECOPD
An uncontrolled feasibility study on using mouth piece ventilation in palliation of dyspnea in subjects with acute exacerbation of COPD without acute hypercapnic respiratory failure.
- Trial name
- NCT03025425
- Testing
- Trilogy 100 ® (Philips Respironics)
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Tampere University Hospital
Chronic Obstructive Pulmonary Disease Exacerbation
Evaluation of Oxygen Delivery Methods in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
To examine the effects of oxygen therapy methods applied as indicated in COPD acute exacerbations on blood gas results and spirometric measurements.
- Trial name
- NCT06561464
- Testing
- EzPAP®, Non-invasive mechanical ventilation (NIMV)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD
The Impact of Indoor Environmental Quality on Symptoms in Patients With Chronic Obstructive Pulmonary Disease
This prospective, monocenter pilot study will investigate the relationship between indoor environmental quality (including air quality, lighting, noise, and thermal conditions), wearable-derived health insights, and…
- Trial name
- COPD-AIR (NCT07799896)
- Testing
- Wearable mobile device, Indoor environmental quality sensor, CAT Questionnaire
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Ziekenhuis Oost-Limburg
Acute Respiratory Disease, COPD Exacerbation Acute
Study of Hospitalised Patients With Acute Respiratory Conditions
The goal of this observational study is to learn about the short- and long-term outcomes of people admitted to hospital with an acute respiratory condition, including exacerbations of chronic lung disease, and to understand…
- Conditions
- Acute Respiratory Disease, COPD Exacerbation Acute, Asthma, Pneumonia
- Trial name
- CHESTY (NCT05095090)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD
Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This investigator-initiated, prospective, single center, randomized, controlled clinical trial enrolled patients with stable Global Initiative for Chronic Obstructive Lung Disease stage II-IV chronic obstruction pulmonary…
- Trial name
- NCT04843696
- Testing
- cuirass ventilator (cuirass diameter 21 cm or 34 cm, Dima Italia Srl.,Bologna, Italy), breathing training, and an educational program (relaxation techniques and a home pacing walking exercise)
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
COPD, AE COPD
Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Models
This study is aimed to collect real-time physiological data using two wearable devices (a biometric ring and a biometric wristband), daily lung mechanical measurements by a handheld oscillometer, and participant-reported symptoms…
- Trial name
- ePredictAECOPD (NCT06802003)
- Testing
- Biometric wearable and handheld devices
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Obstructive Airway Disease
Safety and Efficacy of Inhaled Sedation in Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Brief Summary (Plain Language) This study tests whether using a device called AnaConDa® to give a mild gas medicine (isoflurane) helps people with severe flare-ups of chronic obstructive pulmonary disease (COPD) breathe more…
- Trial name
- NCT07191470
- Testing
- The Anaesthetic Conserving Device (AnaConDa)
- Where
- India
- Volunteers
- 10 people
- Sponsor
- Pandit Bhagwat Dayal Sharma, PGIMS, Rohtak
Chronic Obstructive Lung Disease, Acute Exacerbation of COPD
Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD
INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too.
- Conditions
- Chronic Obstructive Lung Disease, Acute Exacerbation of COPD, Comorbidities and Coexisting Conditions
- Trial name
- NCT05504993
- Testing
- Frequency of AECOPD
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara University
COPD (Chronic Obstructive Pulmonary Disease)
Effectiveness of DITM Versus IMT in COPD Patients
The goal of this clinical trial is to learn if digital inhaled therapy management (DITM) and inspiratory muscle training (IMT), alone or in combination, can improve outcomes in adults aged 40 years and older with symptomatic…
- Trial name
- NCT06958666
- Testing
- Digital Inhaled Therapy Management, Inspiratory Muscle Training
- Where
- 9 sites in China
- Volunteers
- 410 people
- Sponsor
- Sir Run Run Shaw Hospital