Clinical trials: Acute Cholecystitis
Acute Cholecystitis
Conservative Versus Proactive Management of Acute Cholecystitis After EUS-guided Transmural Gallbladder Drainage: FUGITIVE Trial (FUGITIVE)
Patients with gallbladder inflammation (acute cholecystitis) who cannot undergo surgery due to their fragility and surgical risk require a gallbladder drainage.
- Trial name
- FUGITIVE (NCT06967597)
- Testing
- Cholecystoscopy and gallbladder cleaning
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- Hospital General Universitario de Alicante
Acute Cholecystitis, Biliary Colic
Transient ECG Changes in Patients With Acute Biliary Disease
Background: The importance of ischemic ECG changes including St segment elevation, ST segment depression or T wave inversion that indicate myocardial ischemia are well established and require appropriate investigation and…
- Conditions
- Acute Cholecystitis, Biliary Colic, Acute Cholangitis
- Trial name
- NCT01706068
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Ziv Hospital
Cholecystitis, Acute
Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis
The benefit from antibiotic prophylaxis in patients undergoing laparoscopic cholecystectomy for acute cholecystitis is insufficiently known.
- Trial name
- AVAC (NCT02619149)
- Testing
- Piperacillin-tazobactam combination product, Saline solution
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Cholecystitis, Acute
Necessity of Preoperative Empirical Antibiotic Use in Acute Cholecystitis
In this study, the investigators compared the surgical outcomes according to the type of antibiotics before surgery in patients who did not have evidence of systemic infection during acute cholecystitis.
- Trial name
- NCT04661371
- Testing
- Laparoscopic cholecystectomy
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul St. Mary's Hospital
Acute Cholecystitis, Percutaneous Cholecystostomy
Factors Affecting The Recurrence Of Acute Cholecystitis After Treatment With Percutaneous Cholecystostomy
Percutaneous cholecystostomy is used to reduce the complications and mortality associated with surgery in patients with high surgical risk in acute cholecystitis.
- Conditions
- Acute Cholecystitis, Percutaneous Cholecystostomy, Recurrence
- Trial name
- NCT05525442
- Testing
- percutaneous cholecystostomy
- Volunteers
- 102 people
- Sponsor
- Tepecik Training and Research Hospital
Acute Calculous Cholecystitis
Mortality Risk Estimation in Acute Calculous Cholecystitis: Beyond the Tokyo Guidelines
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments, the complication rate of ACC is 20-55%, and the mortality rate is 0.5-15% in recent series.
- Trial name
- ACME (NCT04744441)
- Testing
- CHOLECYSTECTOMY, PERCUTANEOUS CHOLECYSTOSTOMY, EXCLUSIVE ANTIBIOTICS
- Volunteers
- 963 people
- Sponsor
- Hospital del Mar
Acute Cholecystitis, Percutaneous Cholecystostomy
Early Versus Delayed Cholecystectomy After Percutaneous Cholecystostomy in Moderate and Severe Cholecystitis (ESCAPE)
Abstract: Acute cholecystitis (AC) is typically managed according to the 2018 Tokyo Guidelines, with treatment strategies determined by the severity of the disease, patient comorbidities, and hospital capabilities.
- Conditions
- Acute Cholecystitis, Percutaneous Cholecystostomy, Laparoscopic Cholecystectomy
- Trial name
- ESCAPE (NCT07161960)
- Testing
- Laparoscopic cholecystectomy
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Yada Suwan
Cholecystitis, Acute
Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA)
The aim of this study is to evaluate the effect and safety of Floseal in this preliminary prospective trial with patients undergoing acute laparoscopic cholecystectomy for acute cholecystitis
- Trial name
- GLA (NCT01126281)
- Testing
- Laparoscopic Cholecystectomy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Bologna
Cholecystitis, Acute
Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)
This study is intended to evaluate the efficacy and safety of glycopyrrolate as an antisialagogue prior to intubation with the rigid-videostylet(Optiscope®) in the general anesthesia settings.
- Trial name
- NCT03050242
- Testing
- Glycopyrrolate
- Where
- South Korea
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eunah Cho, MD
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Cholecystitis, Gall Stone Pancreatitis
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
Laparoscopic cholecystectomy (removal of the gall bladder via 'keyhole surgery') is a common procedure. This can be performed as an emergency operation when a patient has a complication of gall stones such as acute inflammation…
- Trial name
- NCT01528722
- Testing
- Bupivacaine, Normal saline
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Acute Cholecystitis
Validation and Comparison of Scores for Prediction of RIsk for Post-operative Major Morbidity After Cholecystectomy in Acute Calculous Cholecystitis (SPRIMACC)
The SPRIMACC study is a prospective multicenter observational study with the primary endpoint to prospectively validate the Chole-Risk score in predicting a complicated postoperative course (post-operative major complications…
- Trial name
- SPRIMACC (NCT04995380)
- Testing
- Early Cholecystectomy
- Where
- 2 sites in Italy, Spain
- Volunteers
- 1,261 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Cholecystitis, Cholecystitis, Acute
TAP Block vs External Oblique Plane Block for Laparoscopic Cholecystectomy Surgery
Ultrasound (US) guidedTransversus Abdominis Plane Block (TAPB) is performed by injecting a local anesthetic into the plane between the internal oblique and transverse abdominis muscles and provides analgesia in the anterolateral…
- Conditions
- Cholecystitis, Cholecystitis, Acute, Cholecystitis, Chronic
- Trial name
- NCT06178757
- Testing
- TAPB, EOIB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Cholelithiasis, Cholecystitis, Acute
Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery
This retrospective controlled study aims to evaluate risk factors that affect open conversion in laparoscopic cholecystectomy. Patient characteristics, medical history, biochemical and radiological studies of the patient will…
- Conditions
- Cholelithiasis, Cholecystitis, Acute, Cholecystitis, Chronic, Gallbladder Diseases
- Trial name
- NCT06244589
- Testing
- Laparoscopic cholecystectomy, Open-conversion cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 1,695 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cholecystitis, Acute
SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis
This study aims to understand how different treatment approaches for acute gallbladder inflammation (acute calculous cholecystitis) affect patient outcomes in real-world hospital settings.
- Trial name
- SnapChole (NCT07568080)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Acute Cholecystitis
Cholecystitis Outcomes in the Investigation of Cholecystectomy Versus EUS-GBD
Acute cholecystitis is common in elderly patients and becomes more frequent with increasing age. Standard treatment is laparoscopic cholecystectomy (LCC), but operative treatment may be associated with increased risk in older…
- Trial name
- CHOICE (NCT07678541)
- Testing
- LCC, EUS-GBD
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Oulu University Hospital
Covid19, Appendicitis
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
This study evaluates operative and non-operative management of acute appendicitis (infection or inflammation of the appendix) and acute cholecystitis (inflammation/infection of the gallbladder) in patients with active mild to…
- Conditions
- Covid19, Appendicitis, Cholecystitis, Acute, Cholecystitis; Gallstone
- Trial name
- NCT04748120
- Testing
- Operative management, Non-operative management
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Gallbladder Inflammation
Vitamin C Efficacy in Reducing Post Operative Pain
Opioids are the corner stone in the treatment of post operative pain. Because of the several side effects of opiods, non-steroidal anti-inflammatory drugs are usually added postoperatively to decrease the total requirements of…
- Trial name
- NCT01322061
- Testing
- Ascorbic Acid
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- American University of Beirut Medical Center
Acute Cholecystitis, Gangrenous Cholecystitis
Enhanced Recovery in Laparoscopic Cholecystectomy
The study assesses the impact of the modified enhanced recovery protocol on the results of surgical treatment of patients with acute cholecystitis.
- Trial name
- ERLAC (NCT03754751)
- Testing
- Laparoscopic cholecystectomy with the implementation of modified ERAS program, Laparoscopic cholecystectomy with standard perioperative treatment
- Where
- Russia
- Volunteers
- 189 people
- Sponsor
- Pirogov Russian National Research Medical University
Acute Cholecystitis
Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Unit in Subjects Over and Under 75 Years
The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach.
- Trial name
- GERBILLE (NCT06873295)
- Where
- France
- Volunteers
- 424 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes