Clinical trials: Acute Cholecystitis
Cholecystitis, Chronic Calculous Cholecystitis
Indocyanine Green Fluorescent Cholangiography and Intraoperative Angiography With Laparoscopic Cholecystectomy
This was a double blinded, randomized, controlled trial involved patients underwent laparoscopic cholecystectomy
- Conditions
- Cholecystitis, Chronic Calculous Cholecystitis, Acute Calculous Cholecystitis
- Trial name
- NCT05125653
- Testing
- Indocyanine Green Fluorescent Laparoscopic Cholangiography, White Light
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Cholecystitis, Acute, Cholecystitis; Gangrenous
Risk Factors for Necrotic Cholecystitis During COVID-19 Pandemic.
Gangrenous cholecystitis is the most common complication of acute cholecystitis. Preliminary data showed that COVID-19 patients have a high risk to present necrotic cholecystitis.
- Conditions
- Cholecystitis, Acute, Cholecystitis; Gangrenous, Cholecystitis Suppurative, Covid19
- Trial name
- ChoCO-W (NCT04542512)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poissy-Saint Germain Hospital
Cholecystitis, Acute
Hong Kong Follow up Protocol After EUS Gallbladder Drainage for Acute Cholecistitis
This study evaluates the long-term safety and efficacy of the Hong Kong follow up protocol in patients who will undergo drainage of the gallbladder under endoultrasonography (EUS) guidance in patients with acute cholecistitis not…
- Trial name
- NCT04874103
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Calculous Cholecystitis, Gallbladder Empyema
Role of Intra-Operative Aspiration in Distended GB in LC
Laparoscopic cholecystectomy (LC) is a standard procedure for gallstones and the standard surgical approach for acute calcular cholecystitis, superseding open cholecystectomy for gallbladder (GB) pathologies.
- Conditions
- Acute Calculous Cholecystitis, Gallbladder Empyema, Gallbladder Mucocele
- Trial name
- NCT07378410
- Testing
- Laparoscopic needle
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Aswan University
Cholecystectomy
HOW TO PERFORM SAFELY CHOLECYSTECTOMY FOR ACUTE CHOLECYSTITIS
The aim of this manuscript is to illustrate a new method permitting safe cholecystectomy in terms of complications with respect to the common bile duct (CBD).
- Trial name
- NCT05744999
- Testing
- Coconut technique
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- University of Catania
Acute Cholecystitis, Empyema
Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis
Laparoscopic cholecystectomy (LC) is the current preferred method of cholecystectomy. The role of routine drainage after LC to decrease postoperative morbidity is still an issue of considerable debate.
- Trial name
- NCT01625247
- Testing
- Surgical drainage
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yonsei University
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Success Rate
Comparison of ENGBD and PTGBD in Acute Suppurative Cholecystitis
Comparison of ENGBD and PTGBD methods on clinical outcomes and the difficulty of cholecystectomy in later stage in patients with acute suppurative cholecystitis.
- Trial name
- NCT03701464
- Testing
- Endoscopic naso-gallbladder drainage, Percutaneous gallbladder drainage
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Fluorenscent Image Guided Surgery, Indocyanide Green
Intra-gallbladder or Systemic Indocyanide Green Injection Facilitate Cholecystectomy.
The investigators will collect the pre-operative medical history and arrange physical examination, life quality evaluation, blood and biochemical test.
- Trial name
- NCT03024892
- Testing
- ICG GB, ICG IV, LC conventional
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Acute Cholecystitis
Is it Safe to do Laparoscopic Cholecystectomy for Acute Cholecystitis up to Seven Days?
Objectives: To compare the safety of early (≤72h) versus late (>72h-7days) laparoscopic cholecystectomy (LC) from symptom onset for acute cholecystitis (AC).
- Trial name
- RCT (NCT03999645)
- Testing
- Early laparoscopic cholecystectomy, Late laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour Teaching Hospital
Acute Cholecystitis, Cholecystectomy
Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
The purpose of this study is to compare the clinical outcomes of early versus delayed laparoscopic cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
- Trial name
- NCT01548339
- Testing
- Laparoscopic cholecystectomy
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Lausanne Hospitals
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cholecystitis, Acute
Usefulness of the CADISS® System for the Cleavage of Severe Adhesions in Cholecystectomy
Acute cholecystitis is the most common complication of cholelithiasis. Acute cholecystitis is inflammation of the gallbladder that develops over hours, usually due to an obstruction of the cystic duct by a gallstone.
- Trial name
- NCT05041686
- Testing
- CADISS® System
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- AuXin Surgery SA
Sepsis, Community-acquired Pneumonia
A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients
A Phase 2, Multi-Center, Randomized, Placebo-Controlled, Dose-Finding Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients
- Conditions
- Sepsis, Community-acquired Pneumonia, Urinary Tract Infections, Cholecystitis, Acute
- Trial name
- NCT04612413
- Testing
- Allocetra-OTS
- Where
- 31 sites in Belgium, France and 3 more
- Volunteers
- 148 people
- Sponsor
- Enlivex Therapeutics Ltd.
Acute Calculous Cholecystitis Candidate to Early Cholecystectomy
CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational Study
CHOLE-POSSUM PRO is a prospective multicenter observational study on patients with ACC candidate to EC. The rationale of the study is to validate the CHOLE-POSSUM PRO SCORE for 30-day mortality in this population.
- Trial name
- NCT06908980
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Cholecystectomy, Laparoscopic, Cholangiopancreatography, Endoscopic Retrograde
Does Subtotal Cholecystectomy Rate for Acute Cholecystitis Change With a Previous ERCP?
Study is designed to investigate whether the history of ERCP is associated with subtotal cholecystectomy rates in patients underwent laparoscopic cholecystectomy operations with the diagnosis of acute cholecystitis.
- Trial name
- NCT05728073
- Testing
- ERCP
- Where
- Turkey (Türkiye)
- Volunteers
- 470 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Acute Cholecystitis
Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study
The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital…
- Trial name
- NCT02130245
- Testing
- Early cholecystectomy, Delayed cholecystectomy
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cholecystitis, Acute
How to Predict Postoperative Complications After Early Laparoscopic Cholecystectomy for Acute Cholecystitis: the Chole-Risk Score
Acute calculous cholecystitis (ACC) is the most common complication of gallstone disease, and laparoscopic cholecystectomy is the gold standard treatment.
- Trial name
- CholeRiskScore (NCT04511910)
- Testing
- Early Laparoscopic Cholecystectomy
- Where
- 11 sites in Spain
- Volunteers
- 1,868 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Acute Calculous Cholecystitis
GALLVIA Trial: EUS-Guided vs Transpapillary Gallbladder Drainage for Acute Calculous Cholecystitis
This multicenter, prospective, open-label, randomized controlled trial compares endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with endoscopic transpapillary gallbladder drainage (EGBS) in poor surgical candidates…
- Trial name
- GALLVIA (NCT07536191)
- Testing
- Endoscopic Ultrasound-Guided Gallbladder Drainage, Endoscopic Transpapillary Gallbladder Drainage
- Where
- 5 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Aichi Medical University