Clinical trials: Acute Appendicitis
Gallstones, Appendicitis
Hybrid Transvaginal-Transabdominal Endoscopic Surgery
The is a pilot study to evaluate the safety and efficacy of hybrid transvaginal-transabdominal procedures. Diagnostic peritoneoscopy (visualizing the inside of the abdomen), appendectomy (removal of the appendix), and…
- Conditions
- Gallstones, Appendicitis, Pelvic Pain
- Trial name
- NCT01039129
- Testing
- Endoscopic Cholecystectomy, Endoscopic Appendectomy, Endoscopic Peritoneoscopy
- Where
- United States
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Appendicitis
A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis
To assess the efficacy, safety, tissue distribution of target organ and Population Pharmacokinetic (PPK) of morinidazole and sodium chloride injection with surgery in patients with suppurative or gangrenous appendicitis
- Trial name
- NCT03380793
- Testing
- morinidazole
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Appendicitis, Pregnancy Loss
Laparoscopic Versus Open Appendectomy in Pregnancy
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
- Conditions
- Appendicitis, Pregnancy Loss, Pregnancy Preterm
- Trial name
- NCT05430633
- Testing
- Appendectomy
- Where
- Estonia
- Volunteers
- 109 people
- Sponsor
- North Estonia Medical Centre
Intra-Abdominal Infections, Intestinal Obstruction
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
- Conditions
- Intra-Abdominal Infections, Intestinal Obstruction, Appendicitis Acute, Perforated Viscus
- Trial name
- CLI (NCT06901544)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Acute Appendicitis
Clinical Trial Comparing ERAT vs Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis
Endoscopic retrograde appendicitis therapy (ERAT) is a new and minimally invasive method for the diagnosis and treatment of acute appendicitis.After a positive diagnosis of acute appendicitis is established by either colonoscopic…
- Trial name
- NCT02789865
- Testing
- Ertapenem, Levofloxacin and Metronidazole, Endoscopic retrograde appendicitis therapy (ERAT), Appendectomy
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Acute Uncomplicated Appendicitis
Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children
The majority of children with uncomplicated acute appendicitis may be considered for either a non-operative or an operative management.
- Trial name
- NACAC (NCT07587450)
- Testing
- Amoxi Clavulanate, appendicectomy
- Where
- 10 sites in France
- Volunteers
- 724 people
- Sponsor
- University Hospital, Toulouse
Acute Appendicitis
Preoperative Immature Granulocyte Count and Percentage for Acute Appendisitis
Appendectomy is the most effective treatment option for acute appendisitis, which is the most commen emergent surgical pathology. However with in time period, surgical treatment borders are narrowed.
- Trial name
- NCT04440150
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Abdominal Pain, Acute Pain
Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions.
- Conditions
- Abdominal Pain, Acute Pain, Acute Cholecystitis, Acute Appendicitis
- Trial name
- DETECT_Acute (NCT05651360)
- Testing
- low-dose CT
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 246 people
- Sponsor
- Oslo University Hospital
Acute Appendicitis
Inflammatory Parameters as Predictive Factors for Complicated Appendicitis
Acute appendicitis is a major cause of acute abdomen. Although its diagnosis is clinical, it is often supported by complementary diagnostic tests.
- Trial name
- NCT05116124
- Testing
- dosing of inflammatory parameters
- Volunteers
- 841 people
- Sponsor
- Centro Hospitalar do Tâmega e Sousa
Perforated Appendicitis
Study on Laparoscopic Operation for Perforated Appendicitis
The purpose of this study is to conduct a prospective observational study for the open approach and laparoscopic approach for perforated appendicitis.
- Trial name
- NCT00677989
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Acute Appendicitis
Changes in the Treatment of Acute Appendicitis
The purpose of this study was to analyse the epidemiology, diagnostics, the type of surgical techniques and their development over time, and mortality in acute appendicitis in 68 hospitals in Germany based on routine data between…
- Trial name
- TreatApp (NCT06558760)
- Volunteers
- 31,988 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Acute Appendicitis, Acute Appendicitis With Rupture
Validation and Comparison of the Appendicitis Inflammatory Response Score and Adult Appendicitis Score
Acute appendicitis is one of the most frequent reasons of emergency laparotomy in adults. Symptoms of acute appendicitis overlap with other clinical conditions and might present as a challenge, especially in the early phases.
- Trial name
- NCT04730752
- Testing
- Appendicitis Inflammatory Response, Adult Appendicitis Score
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Nigde Omer Halisdemir University
Acute Pain, Abdomen, Acute
Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain
Appendicitis is a common condition in children 6-17 years of age, and the top reason for emergency surgery in Canada. Children with appendicitis can have very bad pain in their belly.
- Conditions
- Acute Pain, Abdomen, Acute, Abdominal Pain, Appendicitis
- Trial name
- KETOAPP (NCT06160778)
- Testing
- Ketorolac Tromethamine, Morphine Sulfate, normal saline
- Where
- Canada
- Volunteers
- 495 people
- Sponsor
- University of Calgary
Appendicitis
Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)
This prospective trial will randomize patients who have had an appendectomy to two different durations of antibiotic therapy depending on the status of the appendicitis.
- Trial name
- CASA-RELAX (NCT05838248)
- Testing
- antibiotic duration
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Louisville