Clinical trials: Acute Aortic Dissection
Aortic Diseases, Aortic Aneurysm
LANDMARC Study: a Study With Focus on Aorta Ascendens
Rationale: Aortic diameter is currently used as a gold standard in international guidelines for prediction of aorta pathology (aortic aneurysm and aortic dissection).
- Conditions
- Aortic Diseases, Aortic Aneurysm, Aortic Dissection, Aortic Aneurysm, Thoracic
- Trial name
- NCT05655767
- Testing
- 4D-flow MR & CT-scan
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- Maastricht University Medical Center
Aortic Dissection
Shear Stress Endothelial/Hemodynamics in Aortic Dissection and Endothelial Shear Stress-biological Profile
Aortic dissection (AD) is a clinical condition belonging to the broader spectrum of Acute Aortic Syndromes, with high morbidity and mortality and characterised by the sudden formation of a breach within the tonaca intima of the…
- Trial name
- HADES-BP (NCT05745428)
- Testing
- molecular and cellular analyses
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Aortic Dissection
Perioperative Eosinophils Their Recovery in Type A Acute Aortic Dissection Prognosis
Type A acute aortic dissection (TA-AAD) patients are prone to life-threatening complications and death during the acute phase. Currently, little evidence is available with regards to the relationship between eosinophils (EOS) and…
- Trial name
- NCT05409677
- Testing
- This was a retrospective study with no intervention other than normal treatment
- Where
- 2 sites in China
- Volunteers
- 274 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Dissection, Systemic Inflammatory Response Syndrome
Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)
Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with cardiovascular diseases.
- Conditions
- Aortic Dissection, Systemic Inflammatory Response Syndrome, Cardiovascular Diseases (CVD)
- Trial name
- PANDA (NCT06195267)
- Testing
- Sivelestat, Blank control
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Aortic Dissection, Aortic Root Aneurysm
Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions
This study intends to include patients who had aortic root lesions and were treated with Bentall surgery from January 2019 to July 2023 in the First Affiliated Hospital of Xi'an Jiaotong University.
- Conditions
- Aortic Dissection, Aortic Root Aneurysm, Minimally Invasive Surgical Procedures
- Trial name
- Mini-Bentall (NCT06177548)
- Testing
- Minimally invasive Bentall procedure
- Where
- China
- Volunteers
- 350 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Dissection
Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection
Acute DeBakey type I aortic dissection (ATAD) is one of the most lethal surgical emergencies. The conventional operative strategy is hemiarch replacement under cardiopulmonary bypass support to replace the diseased segment of the…
- Trial name
- RADAR (NCT06044259)
- Testing
- AMDS; Artivion, Atlanta, Georgia, US, Conventional hemiarch replacement
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong