Clinical trials: Activity Restriction
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
Stroke
tDCS Combined With Constraint Induced Movement Therapy and Role of GABA Activity in Stroke Recovery
The aim of this study is to determine whether noninvasive brain stimulation in form of active transcranial direct current stimulation (tDCS) combined with constraint induced movement therapy (CIMT) offers an additional benefit as…
- Trial name
- NCT01983319
- Testing
- active anodal transcranial Direct Current Stimulation (tDCS), Constraint Induced Movement Therapy (CIMT)
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Barrett's Esophagus, Overweight and Obesity
CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO).
The increasing incidence of Esophageal Adenocarcinoma (EAC) in several Western countries can be primarily ascribed to risk factors such as obesity, chronic gastroesophageal reflux, dietary habits and alcohol intake.
- Trial name
- CARE-PRO (NCT03813381)
- Testing
- Calorie and protein restriction diet
- Volunteers
- 160 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Healthy Adult
Safety and Effects of High-Intensity Blood Flow Restriction Training in the Rotator Cuff
This study aims to analyze the effects of an 8-week strength training program combining different exercise intensities and blood flow restriction (BFR) conditions on safety, tolerability, muscle adaptations, and physical…
- Trial name
- NCT07404683
- Testing
- High-intensity exercise with BFR, Low-intensity exercise with BFR, High-intensity exercise without BFR
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Overweight and Obesity
Time-restricted Eating and High-intensity Interval Training for Metabolic Health in Adults With Overweight/Obesity
This study will investigate the effects of 12 months periodised time-restricted eating combined with high-intensity interval training compared with a control group on fat mass in adults with overweight/obesity.
- Trial name
- TREHIIT-3 (NCT07036562)
- Testing
- Time-restricted eating and high-intensity interval training
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Obesity
Additional Metabolic and Vascular Effects of Exercise in Patients on Diet-based Weight Loss Programs
This study tests the hypothesis that exercise training can confer additional benefit to patients in weight-loss programs in the form of improvements in either metabolic or vascular parameters or both.
- Trial name
- NCT00929890
- Testing
- General lifestyle, diet and physical activity counselling, Exercise training
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Breast Cancer
Diet Restriction and Exercise-induced Adaptations in Metastatic Breast Cancer
Fifty patients with metastatic breast cancer will be randomly assigned to an acute intervention consisting of both aerobic exercise and caloric restriction administered acutely prior to each of six chemotherapy cycles, or to…
- Trial name
- DREAM (NCT03795493)
- Testing
- Short-term diet and exercise intervention
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Alberta
Aging
CALERIE (Washington University): Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet increases the length of life and prevents some age-related chronic diseases such as cancer, diabetes, and…
- Trial name
- NCT00099138
- Testing
- Caloric Restriction (CR), Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Hip Fractures
The Effects of Fragility Fracture Integrated Rehabilitation Management
To determine the effects of Fragility Fracture Integrated Rehabilitation Management approach in geriatric hip fracture patients (post surgical)
- Trial name
- NCT04760756
- Testing
- Fragility Fracture Integrated Rehabilitation Management
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Zohra Institute of Health Sciences
Asthma
A Study for the Assessment of the Words Used by Patients and Physicians to Express Asthma Symptoms
The purpose of the study is to evaluate the concordance of the most frequently used words by the patients and the physicians to express asthma symptoms and the limitations of daily activities caused by asthma.
- Trial name
- NCT00986219
- Where
- 40 sites in Greece
- Volunteers
- 696 people
- Sponsor
- AstraZeneca
Men, Diet Modification
Dietary Guide in Active Older Adult Men
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men…
- Conditions
- Men, Diet Modification, Obesity, Overweight
- Trial name
- NCT03082807
- Testing
- NCDsport, LCDsport
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
B-cell Acute Lymphoblastic Leukemia, Obesity
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with resistance to chemotherapy in patients with B-ALL.
- Trial name
- IDEAL2 (NCT05082519)
- Testing
- IDEAL2 Intervention
- Where
- 16 sites in United States
- Volunteers
- 240 people
- Sponsor
- Etan Orgel
Chronic Obstructive Pulmonary Disease
Efficacy and Safety Study of QVA149 in COPD Patients
The purpose of this study is to demonstrate that the efficacy of the combination product QVA149 is similar to the efficacy of the combination product umeclidinium/vilanterol on a pre-specified endpoint of FEV1 AUC0-24h while…
- Trial name
- NCT02487446
- Testing
- QVA149, Umeclidinium/vilanterol
- Where
- 58 sites in United States
- Volunteers
- 357 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Pathophysiological Mechanisms of Dyspnea and Activity-limitation in Mild Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a growing cause of death, disability and health care costs in Canada. Nevertheless, COPD remains largely under-diagnosed and under-treated, particularly in its early stages.
- Trial name
- NCT00975403
- Testing
- Dead space breathing, Room air breathing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Type 2 Diabetes
Feasibility of Aerobic Exercise With Blood Flow Restriction Training in People Living With Type 2 Diabetes
The goal of this trial is to learn if blood flow restriction training with treadmill walking is possible for individuals living with type 2 diabetes.
- Trial name
- BOOST-HEALTH (NCT07196371)
- Testing
- Aerobic Training with Blood Flow Restriction, Standard Aerobic Training
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of New Brunswick
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Muscle Strength
The Effect od Beetroot Juice on Forearm Muscle Strength and Muscle EMG Activity After BloodFlow Restriction
The primary aim of the current study is determine the effect of beetroot juice consumption on maximal grip strength and EMG muscle activity
- Trial name
- BFR_EMG (NCT06227091)
- Testing
- Beetroot juice
- Where
- Poland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Dyspnea
Inhaled Fentanyl Citrate & Dyspnea
"Dyspnea" refers to the awareness of breathing discomfort that is typically experienced during exercise in health and disease. In various participant populations, dyspnea is a predictor of disability and death; and contributes to…
- Trial name
- NCT01853449
- Testing
- Fentanyl Citrate, CWS
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McGill University
Plantar Fascitis
Shock Waves Therapy Combined With Leg Stretching in Patients With Plantar Fasciitis
The aim of this study is to evaluate the efficacy of a combination treatment consisting of ESWT and stretching of different muscles in the lower body compared to ESWT treatment alone in patients with plantar fasciitis.
- Trial name
- NCT06466616
- Testing
- Real stretching
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois at Chicago